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Collaborations and top research areas from the last five years
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Coupling of response biomarkers between tumor and peripheral blood in patients undergoing chemoimmunotherapy
Chin, W. L., Cook, A. M., Chee, J., Principe, N., Hoang, T. S., Kidman, J., Hmon, K. P. W., Yeow, Y., Jones, M. E., Hou, R., Denisenko, E., McDonnell, A. M., Hon, C. C., Moody, J., Anderson, D., Yip, S., Cummins, M. M., Stockler, M. R., Kok, P. S. & Brown, C. & 10 others, , 21 Jan 2025, In: Cell Reports Medicine. 6, 1, p. 1-18 18 p., 101882.Research output: Contribution to journal › Article › peer-review
Open Access8 Link opens in a new tab Citations (Scopus) -
Systematic Review and Meta-Analysis of microRNA-7-5p Expression and Biological Significance in Head and Neck Squamous Cell Carcinoma
Brown, R. A. M., Phillips, M., Woo, A. J., Kujan, O., Flukes, S., Winteringham, L. N., Dymond, L. C., Wheeler, F., Pollock, B., Beveridge, D. J., Denisenko, E. & Leedman, P. J., 1 Oct 2025, In: Cancers. 17, 19, 32 p., 3232.Research output: Contribution to journal › Review article › peer-review
Open Access2 Link opens in a new tab Citations (Web of Science) -
Pericyte phenotype switching alleviates immunosuppression and sensitizes vascularized tumors to immunotherapy in preclinical models
Li, Z. J., He, B., Domenichini, A., Satiaputra, J., Wood, K. H., Lakhiani, D. D., Bashaw, A. A., Nilsson, L. M., Li, J., Bastow, E. R., Johansson-Percival, A., Denisenko, E., Forrest, A. R. R., Sakaram, S., Carretero, R., Hämmerling, G. J., Nilsson, J. A., Lee, G. Y. F. & Ganss, R., 17 Sept 2024, In: Journal of Clinical Investigation. 134, 18, 19 p., e179860.Research output: Contribution to journal › Article › peer-review
Open Access15 Link opens in a new tab Citations (Web of Science) -
Spatial transcriptomics reveals discrete tumour microenvironments and autocrine loops within ovarian cancer subclones
Denisenko, E., de Kock, L., Tan, A., Beasley, A. B., Beilin, M., Jones, M. E., Hou, R., Muirí, D. Ó., Bilic, S., Mohan, G. R. K. A., Salfinger, S., Fox, S., Hmon, K. P. W., Yeow, Y., Kim, Y., John, R., Gilderman, T. S., Killingbeck, E., Gray, E. S. & Cohen, P. A. & 2 others, , Dec 2024, In: Nature Communications. 15, 1, 2860.Research output: Contribution to journal › Article › peer-review
Open Access86 Link opens in a new tab Citations (Web of Science) -
Characterization of the humanized FRG mouse model and development of an AAV-LK03 variant with improved liver lobular biodistribution
Cabanes-Creus, M., Navarro, R. G., Liao, S. H. Y., Scott, S., Carlessi, R., Roca-Pinilla, R., Knight, M., Baltazar, G., Zhu, E., Jones, M., Denisenko, E., Forrest, A. R. R., Alexander, I. E., Tirnitz-Parker, J. E. E. & Lisowski, L., 9 Mar 2023, In: Molecular Therapy - Methods and Clinical Development. 28, p. 220-237 18 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Link opens in a new tab Citations (Scopus)
Datasets
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Systematic assessment of tissue dissociation and storage biases in single-cell and single-nucleus RNA-seq workflows
Denisenko, E. (Creator), Guo, B. (Creator), Jones, M. (Creator), Hou, R. (Creator), De Kock, L. (Creator), Lassmann, T. (Creator), Poppe, D. (Contributor), Clement, O. (Creator), Simmons, R. (Creator), Lister, R. (Creator) & Forrest, A. (Creator), Gene Expression Omnibus (NCBI), 11 May 2020
DOI: 10.26182/ybd2-6755, https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE141115
Dataset
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Single Nucleus RNA Sequencing of Pre-Malignant Liver Reveals Disease-Associated Hepatocyte State with HCC Prognostic Potential
Carlessi, R. (Creator), Denisenko, E. (Creator), Boslem, E. (Creator), Köhn-Gaone, J. (Creator), Main, N. (Creator), Abu Bakar, N. D. B. (Creator), Shirolkar, G. (Creator), Jones, M. (Creator), Poppe, D. (Contributor), Dwyer, B. J. (Creator), Jackaman, C. (Creator), Tjiam, C. (Creator), Lister, R. (Creator), Karin, M. (Creator), Fallowfield, J. A. (Creator), Kendall, T. J. (Creator), Forbes, S. J. (Creator), Olynyk, J. K. (Creator), Yeoh, G. (Creator), Forrest, A. (Creator), Ramm, G. (Creator), Febbraio, M. A. (Creator) & Tirnitz-Parker, N. (Creator), Gene Expression Omnibus (NCBI), 12 Apr 2022
DOI: 10.26182/bhy9-q334, https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE200366
Dataset
Projects
- 4 Finished
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CCWA - Mapping and tackling chemotherapy resistance in ovarian cancer
Forrest, A. (Investigator 01), Cohen, P. (Investigator 02) & Denisenko, E. (Investigator 03)
1/01/22 → 30/12/23
Project: Research
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Suzanne Cavanagh ECI Grant - Creating cancer cell maps, using advanced technology, to understand why ovarian cancer keeps growing after treatment
Denisenko, E. (Investigator 01), Forrest, A. (Investigator 02) & Yu, Y. (Investigator 03)
1/03/21 → 30/12/23
Project: Research
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Spatial and single cell transcriptomics to map the interplay between cancer and the surgery-induced wound healing response
Zemek, R. (Investigator 01), Chin, M. (Investigator 02) & Denisenko, E. (Investigator 03)
1/01/21 → 30/06/22
Project: Research
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Suzanne Cavanaugh ECI Grant - Using spatial transcriptomics to identifying factors that govern the varying responses of high-grade serous carcinoma of the ovary (HGSC) to neo-adjuvant chemotherapy
De Kock, L. (Investigator 01), Forrest, A. (Investigator 02), Yu, Y. (Investigator 03) & Denisenko, E. (Investigator 04)
1/01/20 → 30/06/21
Project: Research