Personal profile
Biography
I completed my PhD in 2011 at the Telethon Kids Institute/Murdoch University where I studied the signalling pathways in human blood monocytes in chronic inflammatory disease. Following this I worked at the School of Women's and Infants' health as part of the perinatal sheep research team where I studied the role of inflammation and infection in premature birth. From 2017 I have been laboratory manager of the Cancer Epigenetics laboratory at the Harry Perkins Institute of Medical Research/University of Western Australia and have been researching the role of novel oncogenes in breast and ovarian cancer.
Education/Academic qualification
Biotechnology, PhD, Mechanisms by which interleukin-4 suppresses inflammatory cytokine production by activated human monocytes, Murdoch University
25 Feb 2006 → 31 Oct 2011
Award Date: 30 Nov 2011
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Protocol for Delivery of CRISPR/dCas9 Systems for Epigenetic Editing into Solid Tumors Using Lipid Nanoparticles Encapsulating RNA
Woodward, E. A., Wang, E., Wallis, C., Sharma, R., Tie, A. W. J., Murthy, N. & Blancafort, P., 2024, Epigenome Editing: Methods and Protocols. Jeltsch, A. & Rots, M. G. (eds.). 2 ed. Humana Press Inc., Vol. 2842. p. 267-287 21 p. (Methods in molecular biology (Clifton, N.J.); vol. 2842).Research output: Chapter in Book/Conference paper › Chapter › peer-review
8 Link opens in a new tab Citations (Scopus) -
Epigenetic reactivation of tumor suppressor genes with CRISPRa technologies as precision therapy for hepatocellular carcinoma
Sgro, A., Cursons, J., Waryah, C., Woodward, E. A., Foroutan, M., Lyu, R., Yeoh, G. C. T., Leedman, P. J. & Blancafort, P., Dec 2023, In: Clinical Epigenetics. 15, 1, 24 p., 73.Research output: Contribution to journal › Article › peer-review
Open Access22 Link opens in a new tab Citations (Scopus) -
Synthetic Epigenetic Reprogramming of Mesenchymal to Epithelial States Using the CRISPR/dCas9 Platform in Triple Negative Breast Cancer
Waryah, C., Cursons, J., Foroutan, M., Pflueger, C., Wang, E., Molania, R., Woodward, E., Sorolla, A., Wallis, C., Moses, C., Glas, I., Magalhães, L., Thompson, E. W., Fearnley, L. G., Chaffer, C. L., Davis, M., Papenfuss, A. T., Redfern, A., Lister, R. & Esteller, M. & 1 others, , 4 Aug 2023, In: Advanced Science. 10, 22, 2301802.Research output: Contribution to journal › Article › peer-review
Open Access21 Link opens in a new tab Citations (Scopus) -
The oncogene AAMDC links PI3K-AKT-mTOR signaling with metabolic reprograming in estrogen receptor-positive breast cancer
Golden, E., Rashwan, R., Woodward, E. A., Sgro, A., Wang, E., Sorolla, A., Waryah, C., Tie, W. J., Cuyàs, E., Kardaś, I., Kozlowski, P., Johnstone, E. K. M., See, H. B., Duffy, C., Parry, J., Lagerborg, K. A., Czapiewski, P., Menendez, J. A., Gorczyński, A. & Wasag, B. & 11 others, , 1 Dec 2021, In: Nature Communications. 12, 1, 1920.Research output: Contribution to journal › Article › peer-review
Open Access35 Link opens in a new tab Citations (Web of Science) -
Honeybee venom and melittin suppress growth factor receptor activation in HER2-enriched and triple-negative breast cancer
Duffy, C., Sorolla, A., Wang, E., Golden, E., Woodward, E., Davern, K., Ho, D., Johnstone, E., Pfleger, K., Redfern, A., Iyer, K. S., Baer, B. & Blancafort, P., 1 Dec 2020, In: npj Precision Oncology. 4, 1, 16 p., 24.Research output: Contribution to journal › Article › peer-review
Open Access153 Link opens in a new tab Citations (Scopus)
Datasets
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Additional file 12 of Epigenetic reactivation of tumor suppressor genes with CRISPRa technologies as precision therapy for hepatocellular carcinoma
Sgro, A. (Creator), Cursons, J. (Creator), Waryah, C. (Creator), Woodward, E. A. (Creator), Foroutan, M. (Creator), Lyu, R. (Creator), Yeoh, G. C. T. (Creator), Leedman, P. J. (Creator) & Blancafort, P. (Creator), Figshare, 29 Apr 2023
DOI: 10.6084/m9.figshare.22723108, https://springernature.figshare.com/articles/dataset/Additional_file_12_of_Epigenetic_reactivation_of_tumor_suppressor_genes_with_CRISPRa_technologies_as_precision_therapy_for_hepatocellular_carcinoma/22723108
Dataset
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Additional file 13 of Epigenetic reactivation of tumor suppressor genes with CRISPRa technologies as precision therapy for hepatocellular carcinoma
Sgro, A. (Creator), Cursons, J. (Creator), Waryah, C. (Creator), Woodward, E. A. (Creator), Foroutan, M. (Creator), Lyu, R. (Creator), Yeoh, G. C. T. (Creator), Leedman, P. J. (Creator) & Blancafort, P. (Creator), Figshare, 29 Apr 2023
DOI: 10.6084/m9.figshare.22723111.v1, https://springernature.figshare.com/articles/dataset/Additional_file_13_of_Epigenetic_reactivation_of_tumor_suppressor_genes_with_CRISPRa_technologies_as_precision_therapy_for_hepatocellular_carcinoma/22723111/1
Dataset
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Additional file 16 of Epigenetic reactivation of tumor suppressor genes with CRISPRa technologies as precision therapy for hepatocellular carcinoma
Sgro, A. (Creator), Cursons, J. (Creator), Waryah, C. (Creator), Woodward, E. A. (Creator), Foroutan, M. (Creator), Lyu, R. (Creator), Yeoh, G. C. T. (Creator), Leedman, P. J. (Creator) & Blancafort, P. (Creator), Springer Nature, 30 Apr 2023
DOI: 10.6084/m9.figshare.22723120, https://springernature.figshare.com/articles/dataset/Additional_file_16_of_Epigenetic_reactivation_of_tumor_suppressor_genes_with_CRISPRa_technologies_as_precision_therapy_for_hepatocellular_carcinoma/22723120
Dataset
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Additional file 14 of Epigenetic reactivation of tumor suppressor genes with CRISPRa technologies as precision therapy for hepatocellular carcinoma
Sgro, A. (Creator), Cursons, J. (Creator), Waryah, C. (Creator), Woodward, E. A. (Creator), Foroutan, M. (Creator), Lyu, R. (Creator), Yeoh, G. C. T. (Creator), Leedman, P. J. (Creator) & Blancafort, P. (Creator), Figshare, 29 Apr 2023
DOI: 10.6084/m9.figshare.22723114.v1, https://springernature.figshare.com/articles/dataset/Additional_file_14_of_Epigenetic_reactivation_of_tumor_suppressor_genes_with_CRISPRa_technologies_as_precision_therapy_for_hepatocellular_carcinoma/22723114/1
Dataset
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Additional file 17 of Epigenetic reactivation of tumor suppressor genes with CRISPRa technologies as precision therapy for hepatocellular carcinoma
Sgro, A. (Creator), Cursons, J. (Creator), Waryah, C. (Creator), Woodward, E. A. (Creator), Foroutan, M. (Creator), Lyu, R. (Creator), Yeoh, G. C. T. (Creator), Leedman, P. J. (Creator) & Blancafort, P. (Creator), Figshare, 29 Apr 2023
DOI: 10.6084/m9.figshare.22723123.v1, https://springernature.figshare.com/articles/dataset/Additional_file_17_of_Epigenetic_reactivation_of_tumor_suppressor_genes_with_CRISPRa_technologies_as_precision_therapy_for_hepatocellular_carcinoma/22723123/1
Dataset
Projects
- 2 Finished
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Lionheart FX Automated High-Content Microscope for the QEII Biomedical Research Precinct
Pavlos, N. (Chief Investigator), Barnett, T. (CoPI), Blancafort, P. (CoPI), Chen, K. (CoPI), Chooi, H. (CoPI), Hamzah, J. (CoPI), Hirvonen, L. (CoPI), Ingley, E. (CoPI), Johnstone, L. (CoPI), Kahler, C. (CoPI), Keelan, J. (CoPI), Kular, J. (CoPI), Mullin, B. (CoPI), Nicol, M. (CoPI), Pixley, F. (CoPI), Swaminatha Iyer, I. (CoPI), Waithman, J. (CoPI), Wilson, S. (CoPI) & Woodward, E. (CoPI)
The University of Western Australia
1/01/25 → 31/12/25
Project: Research
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iXon Life Camera with SRFF-Stream for High-Speed Live-Cell Single Molecule Imaging
Swaminatha Iyer, I. (Investigator 01), Lister, R. (Investigator 02), Fox, A. (Investigator 03), Smith, N. (Investigator 04), Choi, Y. S. (Investigator 05), Stubbs, K. (Investigator 06), Lesterhuis, W. (Investigator 07), Blancafort, P. (Investigator 08), Bond, C. (Investigator 09), Jiang, H. (Investigator 10), Geddes, D. (Investigator 11), Chooi, H. (Investigator 12), Sarkar-Tyson, M. (Investigator 13), Evans, C. (Investigator 14), Chen, K. (Investigator 15), Rassell, A. (Investigator 16), Waryah, C. (Investigator 17), Golden, E. (Investigator 18) & Woodward, E. (Investigator 19)
NHMRC National Health and Medical Research Council
3/01/22 → 6/06/22
Project: Research