Debbie Trinder

Associate Professor, BSc PhD W.Aust.

  • The University of Western Australia (M582), 35 Stirling Highway,

    6009 Perth

    Australia

  • 2352 Citations
  • 28 h-Index
19962019
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Research Output 1996 2019

Filter
Article
2 Citations (Scopus)
Open Access
Erythrocyte Indices
Incidence
Health
Iron
Neoplasms
14 Citations (Scopus)

A seven day running training period increases basal urinary hepcidin levels as compared to cycling

Sim, M., Dawson, B., Landers, G., Swinkels, D. W., Tjalsma, H., Wiegerinck, E. T., Trinder, D. & Peeling, P., 9 Apr 2014, In : Journal of the International Society of Sports Nutrition. 11, 1, 9 p.

Research output: Contribution to journalArticle

Open Access
Hepcidins
Running
exercise
Iron
Exercise
174 Citations (Scopus)
Sports
Iron
Hormones
Cytokines
Inflammation
17 Citations (Scopus)

Brain iron accumulation affects myelin-related molecular systems implicated in a rare neurogenetic disease family with neuropsychiatric features

Heidari, M., Johnstone, D. M., Bassett, B., Graham, R. M., Chua, A. C. G., House, M. J., Collingwood, J. F., Bettencourt, C., Houlden, H., Ryten, M., Olynyk, J. K., Trinder, D. & Milward, E. A., Nov 2016, In : Molecular Psychiatry. 21, 11, p. 1599-1607

Research output: Contribution to journalArticle

Open Access
Myelin Sheath
Rare Diseases
Iron
Brain
Transferrin Receptors
12 Citations (Scopus)

Brain transcriptome perturbations in the Hfe−/− mouse model of genetic iron loading

Johnstone, D., Graham, R., Trinder, D., Delima, R., Riveros, C., Olynyk, J., Scott, R., Moscato, P. & Milward, E., 2012, In : Brain Research. 1448, p. 144-152

Research output: Contribution to journalArticle

10 Citations (Scopus)

Brain transcriptome perturbations in the transferrin receptor 2 mutant mouse support the case for brain changes in iron loading disorders, including effects relating to long-term depression and long-term potentiation

Acikyol, B., Graham, R., Trinder, D., House, M., Olynyk, J. K., Scott, R. J., Milward, E. A. & Johnstone, D. M., 2013, In : Neuroscience. 235, p. 119

Research output: Contribution to journalArticle

7 Citations (Scopus)

Changes in Brain Transcripts Related to Alzheimer's Disease in a Model of HFE Hemochromatosis are not Consistent with Increased Alzheimer's Disease Risk

Johnstone, D., Graham, R., Trinder, D., Riveros, C., Olynyk, J., Scott, R., Moscato, P. & Milward, E. A., 2012, In : Journal of Alzheimer's Disease. 30, p. 791-803

Research output: Contribution to journalArticle

19 Citations (Scopus)

Clinical Perspectives on hereditary Hemochromatosis

Ayonrinde, O. T., Milward, E. A., Chua, A. C. G., Trinder, D. & Olynyk, J., 2008, In : Critical Reviews in Clinical Laboratory Sciences. 45, 5, p. 451-484

Research output: Contribution to journalArticle

Hemochromatosis
Iron
Iron Overload
Hepcidins
Iron Metabolism Disorders

Cloning and gastrointestinal expression of rat hepaestin: relationship to other iron transport proteins

Frazer, D. M., Vulpe, C. D., Mckie, A. T., Wilkins, S. J., Trinder, D., Cleghorn, G. J. & Anderson, G. J., 2001, In : American Journal of Gastrointestinal and Liver Physiology. 281, p. G931-G939

Research output: Contribution to journalArticle

64 Citations (Scopus)

Cumulative effects of consecutive running sessions on hemolysis, inflammation and hepcidin activity

Peeling, P., Dawson, B., Goodman, C., Landers, G., Wiegerinck, E. T., Swinkels, D. W. & Trinder, D., 2009, In : European Journal of Applied Physiology. 106, 1, p. on-line

Research output: Contribution to journalArticle

Hepcidins
Ferritins
Hemolysis
Running
Interleukin-6

Detection of HFE Haemochromatosis in the clinic and community using standard erythrocyte tests

Adris, N., Hazedine, S., Bentley, P., Trinder, D., Chua, A. C. G., Powell, L. W., Ramm, L. E., Ramm, G. A. & Olyny, J. K., Feb 2019, In : Blood Cells, Molecules, and Diseases. 74, p. 18-24 7 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Dietary Iron Enhances Colonic Inflammation and IL-6/IL-11-Stat3 Signalling Promoting Colonic Tumor Development in Mice

Chua, A., Klopcic, B., Ho, D., Fu, S., Forrest, C., Croft, K., Olynyk, J., Lawrance, I. & Trinder, D., 2013, In : PLoS One. 8, 11, p. 12pp

Research output: Contribution to journalArticle

Open Access
32 Citations (Scopus)

Disruption of hemochromatosis protein and transferrin receptor 2 causes iron-induced liver injury in mice

Delima, R., Chua, A., Tirnitz-Parker, N., Gan, E. K., Croft, K., Graham, R., Olynyk, J. & Trinder, D., 2012, In : Hepatology. 56, p. 585-592

Research output: Contribution to journalArticle

33 Citations (Scopus)

Effect of iron status on DMT1 expression in duodenal enterocytes from ß2-microglobulin knockout mice

Moos, T., Trinder, D., Morgan, E. H. & Morgan, E., 2002, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 283, September, p. G687-G694

Research output: Contribution to journalArticle

24 Citations (Scopus)

Effects of Cell Proliferation on the Uptake of Transferrin-Bound Iron by Human Hepatoma Cells

Lee, A. W. M., Oates, P. & Trinder, D., 2003, In : Hepatology. 38, 4, p. 967-977

Research output: Contribution to journalArticle

Transferrin Receptors
Transferrin
Hepatocellular Carcinoma
Iron
Cell Proliferation
71 Citations (Scopus)

Effects of exercise on hepcidin response and iron metabolism during recovery

Peeling, P., Dawson, B., Goodman, C., Landers, G., Wiegerinck, E. T., Swinkels, D. W. & Trinder, D., 2009, In : International Journal of Sport Nutrition & Exercise Metabolism. 19, 6, p. 583-597

Research output: Contribution to journalArticle

Hepcidins
exercise
Iron
Exercise
iron
7 Citations (Scopus)

Emu Oil Improves Clinical Indicators of Disease in a Mouse Model of Colitis-Associated Colorectal Cancer

Chartier, L. C., Howarth, G. S., Lawrance, I. C., Trinder, D., Barker, S. J. & Mashtoub, S., 2018, In : Digestive Diseases and Sciences. 63, 1, p. 135–145 11 p.

Research output: Contribution to journalArticle

Colitis
Colorectal Neoplasms
Dextran Sulfate
Azoxymethane
Water Cycle
1 Citation (Scopus)

Emu Oil reduces disease severity in a mouse model of chronic ulcerative colitis

Safaeian, R., Howarth, G. S., Lawrance, I. C., Trinder, D. & Mashtoub, S., 4 Mar 2019, In : Scandinavian Journal of Gastroenterology. 54, 3, p. 273-280 8 p.

Research output: Contribution to journalArticle

Ulcerative Colitis
Peroxidase
emu Oil
Dextran Sulfate
Mucositis

Evaluation of Different Normalization and Analysis Procedures for Illumina Gene Expression Micoarray Data Involving Small Changes

Johnstone, D. M., Riveros, C., Heidari, M., Graham, R., Trinder, D., Berretta, R., Olynyk, J. K., Scott, R. J., Moscato, P. & Milward, E. A., 2013, In : Microarrays. 2, p. 131-152

Research output: Contribution to journalArticle

Open Access
13 Citations (Scopus)

Factors That Affect Serum Levels of Ferritin in Australian Adults and Implications for Follow-Up

Mckinnon, E. J., Rossi, E., Beilby, J., Trinder, D. & Olynyk, J. K., Jan 2014, In : Clinical Gastroenterology and Hepatology. 12, 1, p. 101-108

Research output: Contribution to journalArticle

Ferritins
Body Mass Index
Serum
Reference Values
Iron Overload
37 Citations (Scopus)

Gastrointestinal function, divalent metal transporter-1 expression and intestinal iron absorption

Oates, P., Trinder, D. & Morgan, E., 2000, In : Pflugers Arch-European Journal of Physiology. 440, p. 496-502

Research output: Contribution to journalArticle

2 Citations (Scopus)

Genetics of hereditary hemochromatosis : a clinical perspective

Gan, E. K., Trinder, D., Ayonrinde, O. T. & Olynyk, J., 2009, In : Expert review of endocrinology & metabolism. 4, 3, p. 225-239

Research output: Contribution to journalArticle

Hemochromatosis
Penetrance
Iron
Mutation
Inborn Genetic Diseases
42 Citations (Scopus)

Hepatic Iron Loading in Mice Increases Cholesterol Biosynthesis

Graham, R., Chua, A., Carter, K., Delima, R. D., Johnstone, D., Herbison, C., Firth, M., O'Leary, R., Milward, E. A., Olynyk, J. & Trinder, D., 2010, In : Hepatology. 52, 2, p. 462-471

Research output: Contribution to journalArticle

283 Citations (Scopus)

Hepcidin expression inversely correlates with the expression of duodenal iron transporters and iron absorption in rats

Frazer, D. M., Wilkins, S. J., Becker, E. M., Vulpe, C. D., Mckie, A. T., Trinder, D. & Anderson, G. J., 2002, In : Gastroenterology. 123, 3, p. 835-844

Research output: Contribution to journalArticle

Hepcidins
Iron
Diet
Intestinal Absorption
Transferrin
55 Citations (Scopus)

Hereditary Hemochromastosis in the Post-HFE Era

Olynyk, J., Trinder, D., Ramm, G. A., Britton, R. S. & Bacon, B. R., 2008, In : Hepatology. 48, 3, p. 991-1001

Research output: Contribution to journalArticle

Iron Overload
Hemochromatosis
Genetic Association Studies
Homeostasis
Iron
12 Citations (Scopus)
Transferrin
Ferritins
Iron
Serum
Neoplasms
25 Citations (Scopus)

Inhibition of Uptake of Transferrin-Bound Iron by Human Hepatoma Cells by Nontransferrin-Bound Iron

Trinder, D. & Morgan, E., 1997, In : Hepatology. 26, 3, p. 001-008

Research output: Contribution to journalArticle

Transferrin
Hepatocellular Carcinoma
Iron
Transferrin Receptors
Citric Acid
2 Citations (Scopus)
Hepcidins
Oral Contraceptives
Interleukin-6
Hormones
Iron
42 Citations (Scopus)

Iron: An emerging factor in colorectal carcinogenesis

Chua, A., Klopcic, B., Lawrance, I., Olynyk, J. & Trinder, D., 2010, In : World Journal of Gastroenterology. 16, 6, p. 663-672

Research output: Contribution to journalArticle

Open Access
39 Citations (Scopus)

Iron absorption and hepatic iron uptake are increased in a transferrin receptor 2 (Y245X) mutant mouse model of hemochromatosis type 3

Drake, S. F., Morgan, E., Herbison, C. E., Delima, R., Graham, R. M., Chua, A. C. G., Leedman, P., Fleming, R. E., Bacon, B. R., Olynyk, J. K. & Trinder, D., 2007, In : American Journal of Physiology: Gastrointestinal and Liver Physiology. 292, p. G323-G328

Research output: Contribution to journalArticle

Transferrin Receptors
Iron
Liver
Hepcidins
Gene Expression
13 Citations (Scopus)
287 Downloads (Pure)
Open Access
File
Hepcidins
menstrual cycle
athletes
Menstrual Cycle
Athletes
62 Citations (Scopus)

Iron status and the acute post-exercise hepcidin response in athletes

Peeling, P., Sim, M., Badenhorst, C. E., Dawson, B., Govus, A. D., Abbiss, C. R., Swinkels, D. W. & Trinder, D., 2014, In : PLoS One. 9, 3, p. 6pp

Research output: Contribution to journalArticle

Open Access
Hepcidins
athletes
Ferritins
Athletes
ferritin
14 Citations (Scopus)

Iron uptake from plasma transferrin by a transferrin receptor 2 mutant mouse model of haemochromatosis

Chua, A., Delima, R. D., Morgan, E., Herbison, C. E., Tirnitz-Parker, N., Graham, R., Fleming, R. E., Britton, R. S., Bacon, B. R., Olynyk, J. & Trinder, D., 2010, In : Journal of Hepatology. 52, 2010, p. 425-431

Research output: Contribution to journalArticle

81 Citations (Scopus)

Iron uptake from plasma transferrin by the duodenum is impaired in the HFE knockout mouse

Trinder, D., Olynyk, J., Sly, W. S. & Morgan, E., 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 8, p. 5622-5626

Research output: Contribution to journalArticle

Transferrin
Duodenum
Knockout Mice
Iron
Hemochromatosis
13 Citations (Scopus)

Limited iron export by hepatocytes contributes to hepatic iron-loading in the Hfe knockout mouse

Chua, A., Drake, S. F., Herbison, C. E., Olynyk, J., Leedman, P. & Trinder, D., 2006, In : Journal of Hepatology. 44, 1, p. 176-182

Research output: Contribution to journalArticle

Knockout Mice
Hepatocytes
Iron
Liver
Hemochromatosis
7 Citations (Scopus)

Liver and Serum Iron: Discrete Regulators of Hepatic Hepcidin Expression

Chua, A., Trinder, D. & Olynyk, J., 2011, In : Hepatology. 54, 1, p. 16-19

Research output: Contribution to journalArticle

189 Citations (Scopus)
28 Citations (Scopus)

Mechanisms of ferric citrate uptake by human hepatoma cells

Trinder, D. & Morgan, E., 1998, In : American journal of physiology : gastrointestinal and liver physiology. 275, p. G279-G286

Research output: Contribution to journalArticle

Non-Hfe Iron Overload: Is phlebotomy the Answer?

Hazeldine, S., Trinder, D. & Olynyk, J., 2013, In : Current Hepatitis Reports. 12, 1, p. 20-27

Research output: Contribution to journalArticle

68 Citations (Scopus)
Hemochromatosis
Knockout Mice
Hepatocytes
Iron
Ions

Normal Iron Metabolism and the Pathophysiology of Iron Overload Disorders

Siah, C. W., Ombiga, J., Adams, L., Trinder, D. & Olynyk, J., 2006, In : Clinical Biochemist Reviews. 27, p. 5-16

Research output: Contribution to journalArticle

6 Citations (Scopus)
Hepcidins
Contraception
Interleukin-6
Oral Contraceptives
Hormones

Pathological relationships involving iron and myelin may constitute a shared mechanism linking various rare and common brain diseases

Heidari, M., Gerami, S. H. H., Bassett, B., Graham, R. M. M., Chua, A. C. G., Aryal, R., House, M. J., Collingwood, J. F. F., Bettencourt, C., Houlden, H., Ryten, M., Olynyk, J. K. K., Trinder, D., Johnstone, D. M. M. & Milward, E. A. A., Jan 2016, In : Rare Diseases. 4, 1, 11 p., e1198458.

Research output: Contribution to journalArticle

Open Access
Brain Diseases
Myelin Sheath
Iron
Hemochromatosis
Rare Diseases
28 Citations (Scopus)

Pentoxifylline improves haemoglobin and interleukin-6 levels in chronic kidney disease

Ferrari, P., Mallon, D., Trinder, D. & Olynyk, J., 2010, In : Nephrology. 15, (2010), p. 344-349

Research output: Contribution to journalArticle

Hemochromatosis
Penetrance
Population
Genes
Natural History
8 Citations (Scopus)

Quantitative assay of urinary hepcidin using MALDI-TOF mass spectrometry

Gay, M. C. L., Mullaney, I., Trinder, D., Olynyk, J. & Trengove, R. D., 2010, In : Analytical Methods. 2, 2010, p. 268-274

Research output: Contribution to journalArticle

13 Citations (Scopus)

Screening for HFE and iron overload

Ombiga, J., Tang, K., Adams, L., Trinder, D. & Olynyk, J., 2005, In : Seminars in Liver Disease. 25, 4, p. 402-410

Research output: Contribution to journalArticle

Iron Overload
Genetic Testing
Phlebotomy
Hemochromatosis
Population Control
32 Citations (Scopus)

The effects of carbohydrate ingestion during endurance running on post-exercise inflammation and hepcidin levels

Sim, M., Dawson, B., Landers, G., Wiegerinck, E. T., Swinkels, D. W., Townsend, M-A., Trinder, D. & Peeling, P., 2012, In : European Journal of Applied Physiology. 112, p. 1889-1898

Research output: Contribution to journalArticle