Debbie Trinder

Associate Professor, BSc PhD W.Aust.

  • 2325 Citations
  • 28 h-Index
19962019
If you made any changes in Pure these will be visible here soon.

Research Output 1996 2019

2019

Detection of HFE Haemochromatosis in the clinic and community using standard erythrocyte tests

Adris, N., Hazedine, S., Bentley, P., Trinder, D., Chua, A. C. G., Powell, L. W., Ramm, L. E., Ramm, G. A. & Olyny, J. K., Feb 2019, In : Blood Cells, Molecules, and Diseases. 74, p. 18-24 7 p.

Research output: Contribution to journalArticle

Emu Oil reduces disease severity in a mouse model of chronic ulcerative colitis

Safaeian, R., Howarth, G. S., Lawrance, I. C., Trinder, D. & Mashtoub, S., 4 Mar 2019, In : Scandinavian Journal of Gastroenterology. 54, 3, p. 273-280 8 p.

Research output: Contribution to journalArticle

Ulcerative Colitis
Peroxidase
emu Oil
Dextran Sulfate
Mucositis

Relationship between mean cell volume and development of arthritis in HFE hemochromatosis

Rehman, A., Carroll, G., Trinder, D., Chua, A. & Olynyk, J., Sep 2019, In : Journal of Gastroenterology and Hepatology. 34, p. 98-98 1 p.

Research output: Contribution to journalAbstract/Meeting Abstract

1 Citation (Scopus)

The Impact of Morning versus Afternoon Exercise on Iron Absorption in Athletes

McCormick, R., Moretti, D., McKay, A. K. A., Laarakkers, C. M., Vanswelm, R., Trinder, D., Cox, G. R., Zimmerman, M. B., Sim, M., Goodman, C., Dawson, B. & Peeling, P., 1 Oct 2019, In : Medicine and Science in Sports and Exercise. 51, 10, p. 2147-2155 9 p.

Research output: Contribution to journalArticle

Hepcidins
Athletes
Iron
Exercise
Meals
2018
Open Access
Erythrocyte Indices
Incidence
Health
Iron
Neoplasms
6 Citations (Scopus)

Emu Oil Improves Clinical Indicators of Disease in a Mouse Model of Colitis-Associated Colorectal Cancer

Chartier, L. C., Howarth, G. S., Lawrance, I. C., Trinder, D., Barker, S. J. & Mashtoub, S., 2018, In : Digestive Diseases and Sciences. 63, 1, p. 135–145 11 p.

Research output: Contribution to journalArticle

Colitis
Colorectal Neoplasms
Dextran Sulfate
Azoxymethane
Water Cycle
2017
326 Downloads (Pure)

Anaemia of chronic kidney disease: what we know now.

Krishnan, A., Trinder, D., Chua, A. C-G., Chakera, A., Ramm, G. & Olynyk, J., 3 Feb 2017, In : Journal of Renal and Hepatic Disorders. 1, 1, p. 11-19 9 p.

Research output: Contribution to journalReview article

Open Access
File
Hepcidins
Chronic Renal Insufficiency
Anemia
Iron
Kidney Diseases

Emu oil improves clinical indicators of disease in a mouse model of colitis-associated colorectal cancer

Chartier, L. C., Howarth, G. S., Lawrance, I. C., Trinder, D., Barker, S. J. & Mashtoub, S., Aug 2017, In : Journal of Gastroenterology and Hepatology (Australia). 32, p. 56-56 1 p.

Research output: Contribution to journalAbstract/Meeting Abstract

Emu Oil Reduces Colonic Damage Severity in a Mouse Model of Chronic Ulcerative Colitis

Safaeian, R., Howarth, G. S., Lawrance, I. C., Trinder, D. & Mashtoub, S., Apr 2017, In : FASEB Journal. 31, 1 p.

Research output: Contribution to journalAbstract/Meeting Abstract

2 Citations (Scopus)
Hepcidins
Oral Contraceptives
Interleukin-6
Hormones
Iron

Liver oxidative stress, apoptosis, and autophagy are increased in a mouse model of iron overload

Chua, A. C. G., Domenichini, A., Delima, R. D., Elsegood, C., Olynyk, J. K. & Trinder, D., Aug 2017, In : Journal of Gastroenterology and Hepatology (Australia). 32, p. 4-4 1 p.

Research output: Contribution to journalAbstract/Meeting Abstract

2016
17 Citations (Scopus)

Brain iron accumulation affects myelin-related molecular systems implicated in a rare neurogenetic disease family with neuropsychiatric features

Heidari, M., Johnstone, D. M., Bassett, B., Graham, R. M., Chua, A. C. G., House, M. J., Collingwood, J. F., Bettencourt, C., Houlden, H., Ryten, M., Olynyk, J. K., Trinder, D. & Milward, E. A., Nov 2016, In : Molecular Psychiatry. 21, 11, p. 1599-1607

Research output: Contribution to journalArticle

Open Access
Myelin Sheath
Rare Diseases
Iron
Brain
Transferrin Receptors
11 Citations (Scopus)
Transferrin
Ferritins
Iron
Serum
Neoplasms

Pathological relationships involving iron and myelin may constitute a shared mechanism linking various rare and common brain diseases

Heidari, M., Gerami, S. H. H., Bassett, B., Graham, R. M. M., Chua, A. C. G., Aryal, R., House, M. J., Collingwood, J. F. F., Bettencourt, C., Houlden, H., Ryten, M., Olynyk, J. K. K., Trinder, D., Johnstone, D. M. M. & Milward, E. A. A., Jan 2016, In : Rare Diseases. 4, 1, 11 p., e1198458.

Research output: Contribution to journalArticle

Open Access
Brain Diseases
Myelin Sheath
Iron
Hemochromatosis
Rare Diseases
54 Citations (Scopus)
163 Downloads (Pure)

Redox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeutics

Kalinowski, D. S., Stefani, C., Toyokuni, S., Ganz, T., Anderson, G. J., Subramaniam, N. V., Trinder, D., Olynyk, J. K., Chua, A., Jansson, P. J., Sahni, S., Lane, D. J. R., Merlot, A. M., Kovacevic, Z., Huang, M. L. H., Lee, C. S. & Richardson, D. R., Apr 2016, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1863, 4, p. 727-748 22 p.

Research output: Contribution to journalReview article

Open Access
File
Oxidation-Reduction
Foot
Metals
Reactive Oxygen Species
Neoplasms
2015
5 Citations (Scopus)
Hepcidins
Contraception
Interleukin-6
Oral Contraceptives
Hormones
2014
14 Citations (Scopus)

A seven day running training period increases basal urinary hepcidin levels as compared to cycling

Sim, M., Dawson, B., Landers, G., Swinkels, D. W., Tjalsma, H., Wiegerinck, E. T., Trinder, D. & Peeling, P., 9 Apr 2014, In : Journal of the International Society of Sports Nutrition. 11, 1, 9 p.

Research output: Contribution to journalArticle

Open Access
Hepcidins
Running
exercise
Iron
Exercise
13 Citations (Scopus)

Factors That Affect Serum Levels of Ferritin in Australian Adults and Implications for Follow-Up

Mckinnon, E. J., Rossi, E., Beilby, J., Trinder, D. & Olynyk, J. K., Jan 2014, In : Clinical Gastroenterology and Hepatology. 12, 1, p. 101-108

Research output: Contribution to journalArticle

Ferritins
Body Mass Index
Serum
Reference Values
Iron Overload
13 Citations (Scopus)
273 Downloads (Pure)
Open Access
File
Hepcidins
menstrual cycle
athletes
Menstrual Cycle
Athletes
59 Citations (Scopus)

Iron status and the acute post-exercise hepcidin response in athletes

Peeling, P., Sim, M., Badenhorst, C. E., Dawson, B., Govus, A. D., Abbiss, C. R., Swinkels, D. W. & Trinder, D., 2014, In : PLoS One. 9, 3, p. 6pp

Research output: Contribution to journalArticle

Open Access
Hepcidins
athletes
Ferritins
Athletes
ferritin
2013
10 Citations (Scopus)

Brain transcriptome perturbations in the transferrin receptor 2 mutant mouse support the case for brain changes in iron loading disorders, including effects relating to long-term depression and long-term potentiation

Acikyol, B., Graham, R., Trinder, D., House, M., Olynyk, J. K., Scott, R. J., Milward, E. A. & Johnstone, D. M., 2013, In : Neuroscience. 235, p. 119

Research output: Contribution to journalArticle

36 Citations (Scopus)

Dietary Iron Enhances Colonic Inflammation and IL-6/IL-11-Stat3 Signalling Promoting Colonic Tumor Development in Mice

Chua, A., Klopcic, B., Ho, D., Fu, S., Forrest, C., Croft, K., Olynyk, J., Lawrance, I. & Trinder, D., 2013, In : PLoS One. 8, 11, p. 12pp

Research output: Contribution to journalArticle

Open Access
32 Citations (Scopus)

Evaluation of Different Normalization and Analysis Procedures for Illumina Gene Expression Micoarray Data Involving Small Changes

Johnstone, D. M., Riveros, C., Heidari, M., Graham, R., Trinder, D., Berretta, R., Olynyk, J. K., Scott, R. J., Moscato, P. & Milward, E. A., 2013, In : Microarrays. 2, p. 131-152

Research output: Contribution to journalArticle

Open Access

Non-Hfe Iron Overload: Is phlebotomy the Answer?

Hazeldine, S., Trinder, D. & Olynyk, J., 2013, In : Current Hepatitis Reports. 12, 1, p. 20-27

Research output: Contribution to journalArticle

2012
1 Citation (Scopus)

Brain changes in iron loading disorders

Milward, E., Acikyol, B., Bassett, B., William, E., Graham, R., Delima, R. D., Trinder, D., Olynyk, J. K. & Johnstone, D., 2012, Metal Ions in Neurological Systems. Linert, W. & Kozlowski, H. (eds.). Germany: Springer, p. 17-30

Research output: Chapter in Book/Conference paperChapter

12 Citations (Scopus)

Brain transcriptome perturbations in the Hfe−/− mouse model of genetic iron loading

Johnstone, D., Graham, R., Trinder, D., Delima, R., Riveros, C., Olynyk, J., Scott, R., Moscato, P. & Milward, E., 2012, In : Brain Research. 1448, p. 144-152

Research output: Contribution to journalArticle

7 Citations (Scopus)

Changes in Brain Transcripts Related to Alzheimer's Disease in a Model of HFE Hemochromatosis are not Consistent with Increased Alzheimer's Disease Risk

Johnstone, D., Graham, R., Trinder, D., Riveros, C., Olynyk, J., Scott, R., Moscato, P. & Milward, E. A., 2012, In : Journal of Alzheimer's Disease. 30, p. 791-803

Research output: Contribution to journalArticle

32 Citations (Scopus)

Disruption of hemochromatosis protein and transferrin receptor 2 causes iron-induced liver injury in mice

Delima, R., Chua, A., Tirnitz-Parker, N., Gan, E. K., Croft, K., Graham, R., Olynyk, J. & Trinder, D., 2012, In : Hepatology. 56, p. 585-592

Research output: Contribution to journalArticle

2 Citations (Scopus)

Plasma iron and iron delivery to the tissues

Graham, R., Chua, A. & Trinder, D., 2012, Iron Physiology and Pathophysiology in Humans. Anderson, G. J. & McLaren, G. D. (eds.). United States: Springer Science + Business Media, p. 117-139 (Nutrition and Health).

Research output: Chapter in Book/Conference paperChapter

Sports Anemia

Sim, M., Peeling, P., Dawson, B. & Trinder, D., 2012, Encyclopedia of Exercise Medicine in Health and Disease. Mooren, F. C. (ed.). Germany: SpringerRference, p. 898

Research output: Chapter in Book/Conference paperEntry for encyclopedia/dictionary

31 Citations (Scopus)

The effects of carbohydrate ingestion during endurance running on post-exercise inflammation and hepcidin levels

Sim, M., Dawson, B., Landers, G., Wiegerinck, E. T., Swinkels, D. W., Townsend, M-A., Trinder, D. & Peeling, P., 2012, In : European Journal of Applied Physiology. 112, p. 1889-1898

Research output: Contribution to journalArticle

2011

Hemochromatosis: Molecular Pathology of Liver Diseases

Nelson, J. E., Trinder, D. & Kowdley, K. V., 2011, Molecular Pathology of Liver Diseases. Monga, S. PS. (ed.). New York: Springer, p. 665-676

Research output: Chapter in Book/Conference paperChapter

7 Citations (Scopus)

Liver and Serum Iron: Discrete Regulators of Hepatic Hepcidin Expression

Chua, A., Trinder, D. & Olynyk, J., 2011, In : Hepatology. 54, 1, p. 16-19

Research output: Contribution to journalArticle

2010
42 Citations (Scopus)

Hepatic Iron Loading in Mice Increases Cholesterol Biosynthesis

Graham, R., Chua, A., Carter, K., Delima, R. D., Johnstone, D., Herbison, C., Firth, M., O'Leary, R., Milward, E. A., Olynyk, J. & Trinder, D., 2010, In : Hepatology. 52, 2, p. 462-471

Research output: Contribution to journalArticle

42 Citations (Scopus)

Iron: An emerging factor in colorectal carcinogenesis

Chua, A., Klopcic, B., Lawrance, I., Olynyk, J. & Trinder, D., 2010, In : World Journal of Gastroenterology. 16, 6, p. 663-672

Research output: Contribution to journalArticle

Open Access
13 Citations (Scopus)

Iron uptake from plasma transferrin by a transferrin receptor 2 mutant mouse model of haemochromatosis

Chua, A., Delima, R. D., Morgan, E., Herbison, C. E., Tirnitz-Parker, N., Graham, R., Fleming, R. E., Britton, R. S., Bacon, B. R., Olynyk, J. & Trinder, D., 2010, In : Journal of Hepatology. 52, 2010, p. 425-431

Research output: Contribution to journalArticle

28 Citations (Scopus)

Pentoxifylline improves haemoglobin and interleukin-6 levels in chronic kidney disease

Ferrari, P., Mallon, D., Trinder, D. & Olynyk, J., 2010, In : Nephrology. 15, (2010), p. 344-349

Research output: Contribution to journalArticle

8 Citations (Scopus)

Quantitative assay of urinary hepcidin using MALDI-TOF mass spectrometry

Gay, M. C. L., Mullaney, I., Trinder, D., Olynyk, J. & Trengove, R. D., 2010, In : Analytical Methods. 2, 2010, p. 268-274

Research output: Contribution to journalArticle

2009
64 Citations (Scopus)

Cumulative effects of consecutive running sessions on hemolysis, inflammation and hepcidin activity

Peeling, P., Dawson, B., Goodman, C., Landers, G., Wiegerinck, E. T., Swinkels, D. W. & Trinder, D., 2009, In : European Journal of Applied Physiology. 106, 1, p. on-line

Research output: Contribution to journalArticle

Hepcidins
Ferritins
Hemolysis
Running
Interleukin-6
69 Citations (Scopus)

Effects of exercise on hepcidin response and iron metabolism during recovery

Peeling, P., Dawson, B., Goodman, C., Landers, G., Wiegerinck, E. T., Swinkels, D. W. & Trinder, D., 2009, In : International Journal of Sport Nutrition & Exercise Metabolism. 19, 6, p. 583-597

Research output: Contribution to journalArticle

Hepcidins
exercise
Iron
Exercise
iron
2 Citations (Scopus)

Genetics of hereditary hemochromatosis : a clinical perspective

Gan, E. K., Trinder, D., Ayonrinde, O. T. & Olynyk, J., 2009, In : Expert review of endocrinology & metabolism. 4, 3, p. 225-239

Research output: Contribution to journalArticle

Hemochromatosis
Penetrance
Iron
Mutation
Inborn Genetic Diseases
4 Citations (Scopus)

Hepcidin regulation by hfe and tfr2: is it enough to give a hepatocyte a complex?

Wallace, D. F., Trinder, D. & Subramaniam, V. N., 2009, In : Gastroenterology. 137, 3, p. 1173-1175

Research output: Contribution to journalReview article

Hemochromatosis
Penetrance
Population
Genes
Natural History
42 Citations (Scopus)

The role of transferrin receptor 1 and 2 in transferrin-bound iron uptake in human hepatoma cells

Herbison, C. E., Thorstensen, K., Chua, A., Graham, R., Leedman, P., Olynyk, J. & Trinder, D., 2009, In : American journal of physiology : cell physiology. 297, 6, p. C1567-C1575

Research output: Contribution to journalArticle

Transferrin Receptors
Transferrin
Hepatocellular Carcinoma
Iron
Coordination Complexes
73 Citations (Scopus)

Training surface and intensity : inflammation, hemolysis and hepcidin expression

Peeling, P., Dawson, B., Goodman, C., Landers, G., Wiegerinck, E. T., Swinkels, D. W. & Trinder, D., 2009, In : Medicine & Science in Sports & Exercise. 41, 5, p. 1138-1145

Research output: Contribution to journalArticle

Hepcidins
Hemolysis
Running
Inflammation
Haptoglobins
2008
170 Citations (Scopus)
Sports
Iron
Hormones
Cytokines
Inflammation
19 Citations (Scopus)

Clinical Perspectives on hereditary Hemochromatosis

Ayonrinde, O. T., Milward, E. A., Chua, A. C. G., Trinder, D. & Olynyk, J., 2008, In : Critical Reviews in Clinical Laboratory Sciences. 45, 5, p. 451-484

Research output: Contribution to journalArticle

Hemochromatosis
Iron
Iron Overload
Hepcidins
Iron Metabolism Disorders
26 Citations (Scopus)

HCV, Iron, and Oxidative Stress: The New Choreography of Hepcidin

Trinder, D., Ayonrinde, O. T. & Olynyk, J., 2008, In : Gastroenterology. 134, 1, p. 348-351

Research output: Contribution to journalLetter

55 Citations (Scopus)

Hereditary Hemochromastosis in the Post-HFE Era

Olynyk, J., Trinder, D., Ramm, G. A., Britton, R. S. & Bacon, B. R., 2008, In : Hepatology. 48, 3, p. 991-1001

Research output: Contribution to journalArticle

Iron Overload
Hemochromatosis
Genetic Association Studies
Homeostasis
Iron