Daniela Ulgiati

Dr, BSc PhD W.Aust.

  • The University of Western Australia (M504), 35 Stirling Highway, Room 1.02B, M Block, QEII campus

    6009 Perth

    Australia

  • 328 Citations
  • 12 h-Index
19962017
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Personal profile

Biography

Dr Daniela Ulgiati completed her Bachelor of Science with Honours majoring in pharmacology and physiology and a PhD in immunology and biochemistry at The University of Western Australia. She then won an United States Arthritis Foundation Fellowship for a four year post-doctoral fellowship position at the University of Colorado in Denver. In 2002 she returned to UWA to take up a research and lecturing fellowship and was instated in her current teaching and research position in late 2007.

Funding overview

NIH
Alliance for Lupus Research
Cancer Council of Western Australia
NHMRC

Current projects

Collaborators

Prof Lawrie Abraham, UWA
Dr Paul Besant, UWA
Dr Peter Hollingsworth, PathWest
Dr Kevin Marchbank, University of Newcastle, United Kingdom
Prof Michael Holers, University of Colorado, USA
Dr Susan Boackle, University of Colorado, USA
Dr Betty Tsao, University of California, Los Angeles, USA

Post-doctorate Group Members

Dr Mark Cruikshanks
Dr Mahdad Karimi

Teaching overview

GENE2204 Principles of Genetics (Unit Co-ordinator)
GENE2230 Molecular Genetics (Unit Co-ordinator)
GENE3330 Molecular Genetics and Genomics
BIOC2202 Biochemical Regulation of Cell Function
Graduate Entry Medical Program (GEMP)
IDNT/PODI1134 Introduction to Normal Systems
IMED2210 Normal Systems
BIOC3351 Molecular and Structural Biochemistry
GENE2204 Principles of Genetics
BIOC3352 Cellular and Metabolic Biochemistry
IMED1113 Molecules, Genes and Cells

Research

Dr Ulgiati’s research interest is in the role of complement in health and disease. Her ambition is to clarify the roles of complement and B cell biology in autoimmune disease, using Systemic Lupus Erythematosus (SLE) as a model for this and other autoimmune diseases. Currently, the auto-immune diseases that this research is focused on are lupus and rheumatoid arthritis and it is moving towards the study of lymphomas and other cancers. The work performed in Dr Ulgiati’s laboratory is varied and includes a wide range of molecular biological, biochemical, immunological and genetic techniques. Some of which include Genotyping, Chomatin Assays, ChIP assays, DNA sequencing and cloning, cell culture, stable and transient transfection assays, PCR, DNA binding assays, proteomic analysis, and FACS analysis.

Keywords

  • Animal cell culture
  • Complement biology
  • Molecular biology
  • Transcriptional regulation

Fingerprint Dive into the research topics where Daniela Ulgiati is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 15 Similar Profiles
Complement 3d Receptors Medicine & Life Sciences
B-Lymphocytes Medicine & Life Sciences
Systemic Lupus Erythematosus Medicine & Life Sciences
Genes Medicine & Life Sciences
Chromatin Medicine & Life Sciences
Haplotypes Medicine & Life Sciences
Complement C4 Medicine & Life Sciences
Cells Chemical Compounds

Research Output 1996 2017

  • 328 Citations
  • 12 h-Index
  • 24 Article
  • 10 Conference paper
  • 1 Abstract/Meeting Abstract
  • 1 Literature review

Disease-associated mutations in RP58 disrupt its neuronal functions through a mechanism involving transcriptional regulation

Hemming, I. A., Clement, O., Gladwyn-Ng, I. E., Ng, H. L., See, E., Ngo, L., Ulgiati, D., Pfleger, K. D. G. & Heng, J. I. -T., Aug 2017, In : Journal of Neurochemistry. 142, p. 90-90 1 p.

Research output: Contribution to journalAbstract/Meeting Abstract

3 Citations (Scopus)

Focused transcription from the human CR2/CD21 core promoter is regulated by synergistic activity of TATA and Initiator elements in mature B cells

Taylor, R., Cruickshank, M., Karimi, M., Ng, H., Quail, E., Kaufman, K. M., Harley, J. B., Abraham, L., Tsao, B. P., Boackle, S. A. & Ulgiati, D., Jan 2016, In : CELLULAR & MOLECULAR IMMUNOLOGY. 13, 1, p. 119-131 13 p.

Research output: Contribution to journalArticle

Open Access
B-Lymphocytes
Complement 3d Receptors
TATA Box
B-Lymphoid Precursor Cells
Plasma Cells
2 Citations (Scopus)
232 Downloads (Pure)

Analysis of tandem E-box motifs within human Complement receptor 2 (CR2/CD21) promoter reveals cell specific roles for RP58, E2A, USF and localized chromatin accessibility

Cruickshank, M., Dods, J., Taylor, R., Karimi, M., Fenwick, E., Quail, E., Rea, A., Holers, V. M., Abraham, L. & Ulgiati, D., Jul 2015, In : International Journal of Biochemistry and Cell Biology. 64, p. 107-119 13 p.

Research output: Contribution to journalArticle

Open Access
File
Complement 3d Receptors
E-Box Elements
Chromatin
B-Lymphocytes
Upstream Stimulatory Factors
Open Access
5 Citations (Scopus)

Molecular prioritization strategies to identify functional genetic variants in the cardiovascular disease-associated expression QTL Vanin-1

Kaskow, B. J., Diepeveen, L. A., Michael Proffitt, J. M., Rea, S., Ulgiati, D., Blangero, J., Moses, E. & Abraham, L., 2014, In : European Journal of Human Genetics. In Press, p. 8pp

Research output: Contribution to journalArticle

Projects 2003 2012