Daniel has a background in stem cell biology and neuroscience. During his PhD, he used human stem cell-derived neuronal cultures for disease modelling of Alzheimer’s disease and ataxias and used genetic manipulation to directly generate human neurons from fibroblasts or to generate therapeutic cell populations. He joined Ryan Listers lab at UWA in Perth to learn omics approaches to define cell states at high resolution and to learn bioinformatic skills to interpret them. He now combines stem cell biology, neuroscience, genomics and epigenetics to better understand human biology to improve cell culture systems in the hope of making them a better tool for biomedical research. He is using epigenomics, single cell technology and a broad range of cell culture systems to chart expression and epigenetic configuration of human tissues and their in vitro model systems.