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Christine Thien

Dr, BSc NSW PhD W.Aust., MASI

  • The University of Western Australia (M508), 35 Stirling Highway,

    6009 Perth

    Australia

  • 2465 Citations
  • 23 h-Index
19942018
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Personal profile

Keywords

  • Immune cell signalling
  • Molecular biology of oncogenes

Fingerprint Dive into the research topics where Christine Thien is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 10 Similar Profiles
Protein-Tyrosine Kinases Medicine & Life Sciences
Epidermal Growth Factor Receptor Medicine & Life Sciences
Ubiquitin-Protein Ligases Medicine & Life Sciences
Tyrosine Medicine & Life Sciences
RING Finger Domains Medicine & Life Sciences
Mutation Medicine & Life Sciences
Phosphorylation Medicine & Life Sciences
Proteins Medicine & Life Sciences

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Research Output 1994 2018

1 Citation (Scopus)

3D uniaxial mechanical stimulation induces tenogenic differentiation of tendon-derived stem cells through a PI3K/AKT signaling pathway

Wang, T., Thien, C., Wang, C., Ni, M., Gao, J., Wang, A., Jiang, Q., Tuan, R. S., Zheng, Q. & Zheng, M. H., 29 Mar 2018, In : FASEB Journal. 32, 9, p. 4804-4814

Research output: Contribution to journalArticle

Tendons
Stem cells
Phosphatidylinositol 3-Kinases
Stem Cells
Tissue
10 Citations (Scopus)

Cyclic mechanical stimulation rescues achilles tendon from degeneration in a bioreactor system

Wang, T., Lin, Z., Ni, M., Thien, C., Day, R. E., Gardiner, B., Rubenson, J., Kirk, T. B., Smith, D., Wang, A., Lloyd, D. G., Wang, Y., Zheng, Q. & Zheng, M., Dec 2015, In : Journal of Orthopaedic Research. 33, 12, p. 1888-1896

Research output: Contribution to journalArticle

Achilles Tendon
Bioreactors
Tendons
Tendinopathy
Apoptosis
4 Citations (Scopus)
272 Downloads (Pure)

Loss of c-Cbl E3 ubiquitin ligase activity enhances the development of myeloid leukemia in FLT3-ITD mutant mice

Taylor, S., Thien, C., Dagger, S., Duyvestyn, J., Grove, C., Lee, B. H., Gilliland, D. G. & Langdon, W., 2015, In : Experimental Hematology. 43, 3, p. 191-206

Research output: Contribution to journalArticle

Open Access
File
fms-Like Tyrosine Kinase 3
Myeloid Leukemia
Ubiquitin-Protein Ligases
STAT5 Transcription Factor
Mutation
8 Citations (Scopus)

Dasatinib targets B-lineage cells but does not provide an effective therapy for myeloproliferative disease in c-Cbl RING finger mutant mice

Duyvestyn, J., Taylor, S., Dagger, S., Orandle., M. S., Morse, H. C., Thien, C. & Langdon, W., 9 Apr 2014, In : PLoS One. 9, 4, 10 p., e94717.

Research output: Contribution to journalArticle

Open Access
mutation
mutants
therapeutics
phosphotransferases (kinases)
protein-tyrosine kinases
26 Citations (Scopus)

Flt3 inhibitor AC220 is a potent therapy in a mouse model of myeloproliferative disease driven by enhanced wild-type Flt3 signaling

Taylor, S., Dagger, S., Thien, C., Wikstrom, M. & Langdon, W., 8 Nov 2012, In : Blood. 120, 19, p. 4049-57

Research output: Contribution to journalArticle

Open Access
Recovery
Therapeutics
Phosphotransferases
Mutation
flt3 ligand protein

Projects 1996 2012