• The University of Western Australia (M316), 35 Stirling Highway,

    6009 Perth

    Australia

  • 320 Citations
  • 5 h-Index
20102020
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Fingerprint Dive into the research topics where Christian Pflueger is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 12 Similar Profiles
DNA Methylation Medicine & Life Sciences
Methylation Medicine & Life Sciences
Chromatin Medicine & Life Sciences
Spermatozoa Medicine & Life Sciences
Clustered Regularly Interspaced Short Palindromic Repeats Medicine & Life Sciences
Genes Chemical Compounds
Histones Medicine & Life Sciences
Transcription Chemical Compounds

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Research Output 2010 2019

  • 320 Citations
  • 5 h-Index
  • 6 Article
  • 1 Comment/debate

Harnessing targeted DNA methylation and demethylation using dCas9

Pflueger, C., Swain, T. & Lister, R., 20 Dec 2019, In : Essays in Biochemistry. 63, 6, p. 813-825 13 p.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
DNA Methylation
Genes
Genome
Methylation
16 Citations (Scopus)

A modular dCas9-SunTag DNMT3A epigenome editing system overcomes pervasive off-target activity of direct fusion dCas9-DNMT3A constructs

Pflueger, C., Tan, D., Swain, T., Nguyen, T. V., Pflueger, J., Nefzger, C., Polo, J. M., Ford, E. & Lister, R., Aug 2018, In : Genome Research. 28, 8, p. 1193-1206

Research output: Contribution to journalArticle

Open Access
DNA Methylation
Genome
Methylation
Catalytic Domain
Binding Sites

Conserved roles of mouse DUX and human DUX4 in activating cleavage-stage genes and MERVL/HERVL retrotransposons

Hendrickson, P. G., Doráis, J. A., Grow, E. J., Whiddon, J. L., Lim, J. W., Wike, C. L., Weaver, B. D., Pflueger, C., Emery, B. R., Wilcox, A. L., Nix, D. A., Peterson, C. M., Tapscott, S. J., Carrell, D. T. & Cairns, B. R., 1 Aug 2017, In : Obstetrical and Gynecological Survey. 72, 8, p. 483-484 2 p.

Research output: Contribution to journalComment/debate

15 Citations (Scopus)

Counteracting H3K4 methylation modulators Set1 and Jhd2 co-regulate chromatin dynamics and gene transcription

Ramakrishnan, S., Pokhrel, S., Palani, S., Pflueger, C., Parnell, T. J., Cairns, B. R., Bhaskara, S. & Chandrasekharan, M. B., 21 Jun 2016, In : Nature Communications. 7, 11949.

Research output: Contribution to journalArticle

Open Access
chromatin
methylation
Methylation
Transcription
genes
7 Citations (Scopus)

Interaction of the Jhd2 Histone H3 Lys-4 Demethylase with Chromatin Is Controlled by Histone H2A Surfaces and Restricted by H2B Ubiquitination

Huang, F., Ramakrishnan, S., Pokhrel, S., Pflueger, C., Parnell, T. J., Kasten, M. M., Currie, S. L., Bhachech, N., Horikoshi, M., Graves, B. J., Cairns, B. R., Bhaskara, S. & Chandrasekharan, M. B., 27 Nov 2015, In : Journal of Biological Chemistry. 290, 48, p. 28760-28777 18 p.

Research output: Contribution to journalArticle

Ubiquitination
Histones
Chromatin
Methylation
Association reactions

Projects 2019 2020

Dissecting gene interactions modulating cancer progression

Cruickshank, M., Pflueger, C., Kaur, P., Jones, L., Joo, E. & Novakovic, B.

Cancer Council Australia

1/01/1930/06/20

Project: Research