Research output per year
Research output per year
Personal profile
Biography
Dr Charlene Waryah is a Postdoctoral Research Fellow with expertise in cancer biology, microbiology and epigenetics. Based at Harry Perkins Institute of Medical Research under the guidance of A/Prof Pilar Blancafort, Dr Waryah leads CRISPR epigenetic editing projects within the Cancer Epigenetics laboratory. Her current research interest is in the development of novel epigenome engineering tools to reprogram dyregulated cells with a focus on molecular therapeutics.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research expertise keywords
- Cancer Epigenetics
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Epigenetic reactivation of tumor suppressor genes with CRISPRa technologies as precision therapy for hepatocellular carcinoma
Sgro, A., Cursons, J., Waryah, C., Woodward, E. A., Foroutan, M., Lyu, R., Yeoh, G. C. T., Leedman, P. J. & Blancafort, P., Dec 2023, In: Clinical Epigenetics. 15, 1, 24 p., 73.Research output: Contribution to journal › Article › peer-review
Open Access9 Citations (Scopus) -
Synthetic Epigenetic Reprogramming of Mesenchymal to Epithelial States Using the CRISPR/dCas9 Platform in Triple Negative Breast Cancer
Waryah, C., Cursons, J., Foroutan, M., Pflueger, C., Wang, E., Molania, R., Woodward, E., Sorolla, A., Wallis, C., Moses, C., Glas, I., Magalhães, L., Thompson, E. W., Fearnley, L. G., Chaffer, C. L., Davis, M., Papenfuss, A. T., Redfern, A., Lister, R., Esteller, M., & 1 others, 4 Aug 2023, In: Advanced Science. 10, 22, 2301802.Research output: Contribution to journal › Article › peer-review
Open Access10 Citations (Scopus) -
Unpacking the Complexity of Epithelial Plasticity: From Master Regulator Transcription Factors to Non-Coding RNAs
Waryah, C., Alves, E., Mazzieri, R., Dolcetti, R., Thompson, E. W., Redfern, A. & Blancafort, P., Jun 2023, In: Cancers. 15, 12, 3152.Research output: Contribution to journal › Review article › peer-review
Open Access1 Citation (Scopus) -
The oncogene AAMDC links PI3K-AKT-mTOR signaling with metabolic reprograming in estrogen receptor-positive breast cancer
Golden, E., Rashwan, R., Woodward, E. A., Sgro, A., Wang, E., Sorolla, A., Waryah, C., Tie, W. J., Cuyàs, E., Kardaś, I., Kozlowski, P., Johnstone, E. K. M., See, H. B., Duffy, C., Parry, J., Lagerborg, K. A., Czapiewski, P., Menendez, J. A., Gorczyński, A., Wasag, B., & 11 others, 1 Dec 2021, In: Nature Communications. 12, 1, 1920.Research output: Contribution to journal › Article › peer-review
Open Access22 Citations (Scopus) -
Activating PTEN Tumor Suppressor Expression with the CRISPR/dCas9 System
Moses, C., Nugent, F., Waryah, C. B., Garcia-Bloj, B., Harvey, A. R. & Blancafort, P., 1 Mar 2019, In: Molecular Therapy - Nucleic Acids. 14, p. 287-300 14 p.Research output: Contribution to journal › Article › peer-review
Open Access72 Citations (Scopus)
Datasets
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Additional file 14 of Epigenetic reactivation of tumor suppressor genes with CRISPRa technologies as precision therapy for hepatocellular carcinoma
Sgro, A. (Creator), Cursons, J. (Creator), Waryah, C. (Creator), Woodward, E. (Creator), Foroutan, M. (Creator), Lyu, R. (Creator), Yeoh, G. (Creator), Leedman, P. (Creator) & Blancafort, P. (Creator), Figshare, 29 Apr 2023
DOI: 10.6084/m9.figshare.22723114.v1, https://springernature.figshare.com/articles/dataset/Additional_file_14_of_Epigenetic_reactivation_of_tumor_suppressor_genes_with_CRISPRa_technologies_as_precision_therapy_for_hepatocellular_carcinoma/22723114/1
Dataset
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Additional file 15 of Epigenetic reactivation of tumor suppressor genes with CRISPRa technologies as precision therapy for hepatocellular carcinoma
Sgro, A. (Creator), Cursons, J. (Creator), Waryah, C. (Creator), Woodward, E. (Creator), Foroutan, M. (Creator), Lyu, R. (Creator), Yeoh, G. (Creator), Leedman, P. (Creator) & Blancafort, P. (Creator), Figshare, 29 Apr 2023
DOI: 10.6084/m9.figshare.22723117.v1, https://springernature.figshare.com/articles/dataset/Additional_file_15_of_Epigenetic_reactivation_of_tumor_suppressor_genes_with_CRISPRa_technologies_as_precision_therapy_for_hepatocellular_carcinoma/22723117/1
Dataset
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Additional file 13 of Epigenetic reactivation of tumor suppressor genes with CRISPRa technologies as precision therapy for hepatocellular carcinoma
Sgro, A. (Creator), Cursons, J. (Creator), Waryah, C. (Creator), Woodward, E. (Creator), Foroutan, M. (Creator), Lyu, R. (Creator), Yeoh, G. (Creator), Leedman, P. (Creator) & Blancafort, P. (Creator), Figshare, 30 Apr 2023
DOI: 10.6084/m9.figshare.22723111, https://springernature.figshare.com/articles/dataset/Additional_file_13_of_Epigenetic_reactivation_of_tumor_suppressor_genes_with_CRISPRa_technologies_as_precision_therapy_for_hepatocellular_carcinoma/22723111
Dataset
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Additional file 17 of Epigenetic reactivation of tumor suppressor genes with CRISPRa technologies as precision therapy for hepatocellular carcinoma
Sgro, A. (Creator), Cursons, J. (Creator), Waryah, C. (Creator), Woodward, E. (Creator), Foroutan, M. (Creator), Lyu, R. (Creator), Yeoh, G. (Creator), Leedman, P. (Creator) & Blancafort, P. (Creator), Figshare, 29 Apr 2023
DOI: 10.6084/m9.figshare.22723123, https://springernature.figshare.com/articles/dataset/Additional_file_17_of_Epigenetic_reactivation_of_tumor_suppressor_genes_with_CRISPRa_technologies_as_precision_therapy_for_hepatocellular_carcinoma/22723123
Dataset
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Additional file 13 of Epigenetic reactivation of tumor suppressor genes with CRISPRa technologies as precision therapy for hepatocellular carcinoma
Sgro, A. (Creator), Cursons, J. (Creator), Waryah, C. (Creator), Woodward, E. (Creator), Foroutan, M. (Creator), Lyu, R. (Creator), Yeoh, G. (Creator), Leedman, P. (Creator) & Blancafort, P. (Creator), Figshare, 29 Apr 2023
DOI: 10.6084/m9.figshare.22723111.v1, https://springernature.figshare.com/articles/dataset/Additional_file_13_of_Epigenetic_reactivation_of_tumor_suppressor_genes_with_CRISPRa_technologies_as_precision_therapy_for_hepatocellular_carcinoma/22723111/1
Dataset
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Core infrastructure: high-throughput nanodrop spectrophotometer
Kretzmann, J., Evans, C., Choi, Y. S., Waryah, C., Sarkar-Tyson, M., Wang, T., Bond, C., Vrielink, A., Smith, N., Lesterhuis, W., Marshall, A., Stubbs, K., Breese, K., Chen, K., Smithers, L., Wylie, B., Wang, E. & Blancafort, P.
NHMRC National Health and Medical Research Council
15/03/24 → 31/12/24
Project: Research
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NHMRC Equipment Grant qPCR
Pflueger, C., Lister, R., Laing, N., Ravenscroft, G., Morahan, G., Leedman, P., Blancafort, P., Forrest, A., Nilsson, J., Waryah, C., Chee, J., Nowak, A. & Gaudieri, S.
NHMRC National Health and Medical Research Council
14/02/22 → 10/02/23
Project: Research
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iXon Life Camera with SRFF-Stream for High-Speed Live-Cell Single Molecule Imaging
Swaminatha Iyer, I., Lister, R., Fox, A., Smith, N., Choi, Y. S., Stubbs, K., Lesterhuis, W., Blancafort, P., Bond, C., Jiang, H., Geddes, D., Chooi, H., Sarkar-Tyson, M., Evans, C., Chen, K., Rassell, A., Waryah, C., Golden, E. & Woodward, E.
NHMRC National Health and Medical Research Council
3/01/22 → 6/06/22
Project: Research
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Epigenome editing to re-activate PWS genes
Blancafort, P., Waryah, C. & Wang, E.
Prader-Willi Research Foundation Australia Ltd
4/01/21 → 3/01/22
Project: Research