Cecilia Prele

Search results

• 2021

  A cGAS-dependent response links DNA damage and senescence in alveolar epithelial cells: A potential drug target in IPF

  Schuliga, M., Kanwal, A., Read, J., Blokland, K. E. C., Burgess, J. K., Prêle, C. M., Mutsaers, S. E., Grainge, C., Thomson, C., James, A., Bartlett, N. W. & Knight, D. A., Nov 2021, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 321, 5, p. L859-L871

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Idiopathic Pulmonary Fibrosis 100%
  • Alveolar Epithelial Cells 93%
  • DNA Damage 72%
  • Cellular Senescence 70%
  • Pharmaceutical Preparations 34%
  1 Citation (Scopus)

• A senescence bystander effect in human lung fibroblasts

  Waters, D. W., Schuliga, M., Pathinayake, P. S., Wei, L., Tan, H. Y., Blokland, K. E. C., Jaffar, J., Westall, G. P., Burgess, J. K., Prêle, C. M., Mutsaers, S. E., Grainge, C. L. & Knight, D. A., Sep 2021, In: Biomedicines. 9, 9, 1162.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Conditioned Culture Medium 100%
  • Bystander Effect 93%
  • Fibroblasts 49%
  • Etoposide 46%
  • Histone 35%
  1 Citation (Scopus)

• Keloid fibroblasts have elevated and dysfunctional mechanotransduction signaling that is independent of TGF-β

  Deng, Z., Subilia, M., Chin, I. L., Hortin, N., Stevenson, A. W., Wood, F. M., Prêle, C. M., Choi, Y. S. & Fear, M. W., Oct 2021, In: Journal of Dermatological Science. 104, 1, p. 11-20

  Research output: Contribution to journal › Article › peer-review

  • Keloid 100%
  • Fibroblasts 55%
  • Blebbistatin 37%
  • Protein 31%
  • Inducer 21%

• Reduced socs1 expression in lung fibroblasts from patients with ipf is not mediated by promoter methylation or mir155

  Prêle, C. M., Iosifidis, T., McAnulty, R. J., Pearce, D. R., Badrian, B., Miles, T., Jamieson, S. E., Ernst, M., Thompson, P. J., Laurent, G. J., Knight, D. A. & Mutsaers, S. E., 2021, In: Biomedicines. 9, 5, 498.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Idiopathic Pulmonary Fibrosis 100%
  • Methylation 75%
  • Fibroblasts 61%
  • Lung 44%
  • Collagen 39%

• The epigenetics of keloids

  Stevenson, A. W., Deng, Z., Allahham, A., Prêle, C. M., Wood, F. M. & Fear, M. W., Aug 2021, In: Experimental Dermatology. 30, 8, p. 1099-1114 16 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Keloid 100%
  • Epigenomics 65%
  • Modification 41%
  • MicroRNA 23%
  • Cicatrix 21%
  4 Citations (Scopus)
• 2020

  Identification of Differentially Methylated CpG Sites in Fibroblasts from Keloid Scars

  Alghamdi, M. A., Wallace, H. J., Melton, P. E., Moses, E. K., Stevenson, A., Al-Eitan, L. N., Rea, S., Duke, J. M., Danielsen, P. L., Prêle, C. M., Wood, F. M. & Fear, M. W., 28 Jun 2020, In: Biomedicines. 8, 7, 16 p., 181.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Keloid 100%
  • Cytosine 89%
  • Cicatrix 65%
  • Fibroblasts 55%
  • Skin 34%
  5 Citations (Scopus)

• Immunopathobiology of chronic lung disease

  Prêle, C. M. & Hoyne, G. F., 2020, In: Clinical & Translational Immunology. 9, 8, e1170.

  Research output: Contribution to journal › Editorial

  Open Access
  1 Citation (Scopus)

• Mesothelial cells regulate immune responses in health and disease: role for immunotherapy in malignant mesothelioma

  Mutsaers, S. E., Pixley, F. J., Prêle, C. M. & Hoyne, G. F., Jun 2020, In: Current Opinion in Immunology. 64, p. 88-109 22 p.

  Research output: Contribution to journal › Review article › peer-review

  • Malignant Mesothelioma 100%
  • Immunotherapy 72%
  • Immune System 65%
  • Epithelium 62%
  • Mesothelioma 48%
  2 Citations (Scopus)

• Self DNA perpetuates IPF lung fibroblast senescence in a cGAS-dependent manner

  Schuliga, M., Read, J., Blokland, K. E., Waters, D. W., Burgess, J., Prele, C., Mutsaers, S. E., Jaffar, J., Westall, G., Reid, A., James, A., Grainge, C. & Knight, D. A., 27 Mar 2020, (E-pub ahead of print) In: Clinical Science.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Idiopathic Pulmonary Fibrosis 100%
  • Fibroblasts 61%
  • DNA 46%
  • Lung 44%
  • Mitochondrial DNA 29%
  16 Citations (Web of Science)

  34 Downloads (Pure)

• Senescence of IPF Lung Fibroblasts Disrupt Alveolar Epithelial Cell Proliferation and Promote Migration in Wound Healing

  Blokland, K. E. C., Waters, D. W., Schuliga, M., Read, J., Pouwels, S. D., Grainge, C. L., Jaffar, J., Westall, G., Mutsaers, S. E., Prêle, C. M., Burgess, J. K. & Knight, D. A., 24 Apr 2020, In: Pharmaceutics. 12, 4

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Conditioned Culture Medium 100%
  • Idiopathic Pulmonary Fibrosis 80%
  • Alveolar Epithelial Cells 75%
  • Collagen 63%
  • Wound Healing 58%
  11 Citations (Scopus)

• The contribution of animal models to understanding the role of the immune system in human idiopathic pulmonary fibrosis

  Miles, T., Hoyne, G. F., Knight, D. A., Fear, M. W., Mutsaers, S. E. & Prêle, C. M., 1 Jan 2020, In: Clinical & Translational Immunology. 9, 7, p. e1153 e1153.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Idiopathic Pulmonary Fibrosis 100%
  • Immune System 65%
  • Animal Models 59%
  • Pulmonary Fibrosis 47%
  • Lung 44%
  5 Citations (Scopus)

• The extracellular matrix and mechanotransduction in pulmonary fibrosis

  Deng, Z., Fear, M. W., Suk Choi, Y., Wood, F. M., Allahham, A., Mutsaers, S. E. & Prêle, C. M., Sep 2020, In: The International Journal of Biochemistry & Cell Biology. 126, p. 105802

  Research output: Contribution to journal › Article › peer-review

  • Pulmonary Fibrosis 100%
  • Collagen 82%
  • Disorder 74%
  • Extracellular Matrix 73%
  • Lung 46%
  15 Citations (Scopus)

• The Role of IL-6 in Skin Fibrosis and Cutaneous Wound Healing

  Johnson, B. Z., Stevenson, A. W., Prêle, C. M., Fear, M. W. & Wood, F. M., 30 Apr 2020, In: Biomedicines. 8, 5, 101.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Wound Healing 100%
  • Protective 94%
  • Interleukin-6 87%
  • Fibrosis 84%
  • Skin 62%
  53 Citations (Scopus)
• 2019

  Ephrin-A2 affects wound healing and scarring in a murine model of excisional injury

  Wijeratne, D., Rodger, J., Stevenson, A., Wallace, H., Prêle, C. M., Wood, F. M. & Fear, M. W., May 2019, In: Burns. 45, 3, p. 682-690 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Ephrin-A2 100%
  • Ephrins 78%
  • Ephrin-A5 78%
  • Wound Healing 47%
  • Cicatrix 46%
  3 Citations (Scopus)

• Inhibition of collagen production delays malignant mesothelioma tumor growth in a murine model

  Abayasiriwardana, K. S., Wood, M. K., Prêle, C. M., Birnie, K. A., Robinson, B. W., Laurent, G. J., McAnulty, R. J. & Mutsaers, S. E., 5 Mar 2019, In: Biochemical and Biophysical Research Communications. 510, 2, p. 198-204 7 p.

  Research output: Contribution to journal › Article › peer-review

  • thiazolidine-4-carboxylic acid 100%
  • Malignant Mesothelioma 85%
  • Collagen 66%
  • Mesothelioma 55%
  • Growth 35%
  6 Citations (Scopus)

• MicroRNA Signatures in Malignant Pleural Mesothelioma Effusions

  Birnie, K. A., Prele, C. M., Musk, A. W., de Klerk, N., Lee, Y. C. G., Fitzgerald, D., Allcock, R. J. N., Thompson, P. J., Creaney, J., Badrian, B. & Mutsaers, S. E., 31 Jul 2019, In: Disease Markers. 9 p., 8628612.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Malignant Pleural Effusion 100%
  • MicroRNA 89%
  • Malignant Mesothelioma 88%
  • Pleural Effusion 76%
  • Biological Marker 65%
  12 Citations (Scopus)

• Resequencing study confirms host defense and cell senescence gene variants contribute to the risk of idiopathic pulmonary fibrosis

  Global IPF Consortium, 15 Jul 2019, In: American Journal of Respiratory and Critical Care Medicine.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Idiopathic Pulmonary Fibrosis 100%
  • Cellular Senescence 91%
  • Genes 33%
  • Alleles 20%
  • Genome-Wide Association Study 14%
  50 Citations (Scopus)

• STAT3 regulates the onset of oxidant-induced senescence in lung fibroblasts

  Waters, D. W., Blokland, K. E. C., Pathinayake, P. S., Wei, L., Schuliga, M., Jaffar, J., Westall, G. P., Hansbro, P. M., Prele, C. M., Mutsaers, S. E., Bartlett, N. W., Burgess, J. K., Grainge, C. L. & Knight, D. A., Jul 2019, In: American Journal of Respiratory Cell and Molecular Biology.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • STAT3 Transcription Factor 100%
  • Oxidants 86%
  • Superoxide 81%
  • Hydrogen Peroxide 63%
  • Fibroblasts 61%
  35 Citations (Web of Science)

  450 Downloads (Pure)
• 2018

  Cross-talk between human airway epithelial cells and 3T3-J2 feeder cells involves partial activation of human MET by murine HGF

  Hynds, R. E., Gowers, K. H. C., Nigro, E., Butler, C. R., Bonfanti, P., Giangreco, A., Prêle, C. M. & Janes, S. M., 2018, In: PLoS One. 13, 5, p. e0197129 e0197129.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • STAT6 Transcription Factor 100%
  • hepatocyte growth factor 97%
  • Feeder Cells 86%
  • epithelial cells 55%
  • Epithelial Cells 45%
  6 Citations (Web of Science)

• Fibroblast senescence in the pathology of idiopathic pulmonary fibrosis

  Waters, D. W., Blokland, K. E. C., Pathinayake, P. S., Burgess, J. K., Mutsaers, S. E., Prêle, C. M., Schuliga, M., Grainge, C. L. & Knight, D. A., Aug 2018, In: American Journal of Physiology: Lung Cellular and Molecular Physiology. 315, 2, p. L162-L172 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Idiopathic Pulmonary Fibrosis 100%
  • Fibroblasts 61%
  • Pathology 52%
  • cdc Genes 17%
  • STAT3 Transcription Factor 16%
  70 Citations (Scopus)

• Mitochondrial dysfunction contributes to the senescent phenotype of IPF lung fibroblasts

  Schuliga, M., Pechkovsky, D. V., Read, J., Waters, D. W., Blokland, K. E. C., Reid, A. T., Hogaboam, C. M., Khalil, N., Burgess, J. K., Prêle, C. M., Mutsaers, S. E., Jaffar, J., Westall, G., Grainge, C. & Knight, D. A., Dec 2018, In: Journal of Cellular and Molecular Medicine. 22, 12, p. 5847-5861 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Idiopathic Pulmonary Fibrosis 100%
  • Fibroblasts 61%
  • Superoxides 55%
  • Phenotype 49%
  • Lung 44%
  41 Citations (Web of Science)

• PD-1 up-regulation on CD4+ T cells promotes pulmonary fibrosis through STAT3-mediated IL-17A and TGF-β1 production

  Celada, L. J., Kropski, J. A., Herazo-Maya, J. D., Luo, W., Creecy, A., Abad, A. T., Chioma, O. S., Lee, G., Hassell, N. E., Shaginurova, G. I., Wang, Y., Johnson, J. E., Kerrigan, A., Mason, W. R., Baughman, R. P., Ayers, G. D., Bernard, G. R., Culver, D. A., Montgomery, C. G., Maher, T. M. & 10 others, Molyneaux, P. L., Noth, I., Mutsaers, S. E., Prele, C. M., Stokes Peebles, R., Newcomb, D. C., Kaminski, N., Blackwell, T. S., Van Kaer, L. & Drake, W. P., 26 Sep 2018, In: Science Translational Medicine. 10, 460, 15 p., eaar8356.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • STAT3 Transcription Factor 100%
  • Pulmonary Fibrosis 95%
  • Interleukin-17 87%
  • Transforming Growth Factors 87%
  • Up-Regulation 59%
  103 Citations (Scopus)
• 2017

  Idiopathic pulmonary fibrosis and a role for autoimmunity

  Hoyne, G. F., Elliott, H., Mutsaers, S. E. & Prele, C., 25 Apr 2017, (E-pub ahead of print) In: Immunology and Cell Biology. 95, p. 577–583 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Idiopathic Pulmonary Fibrosis 100%
  • Interstitial 86%
  • Autoimmunity 80%
  • Antigen 69%
  • Protein 34%
  36 Citations (Scopus)

• Targeting microRNA to improve diagnostic and therapeutic approaches for malignant mesothelioma

  Birnie, K. A., Prêle, C. M., Thompson, P. J., Badrian, B. & Mutsaers, S. E., 2017, In: Oncotarget. 8, 44, p. 78193-78207 15 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Malignant Mesothelioma 100%
  • Mesothelioma 78%
  • MicroRNAs 69%
  • Asbestos 58%
  • Pleura 19%
  18 Citations (Scopus)
• 2016

  A subset of malignant mesothelioma tumors retain osteogenic potential

  Lansley, S. M., Pedersen, B., Robinson, C., Searles, R. G., Sterrett, G., Van Bruggen, I., Lake, R. A., Mutsaers, S. E. & Prele, C., 25 Nov 2016, In: Scientific Reports. 6, 36349.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Malignant Mesothelioma 100%
  • Neoplasms 26%
  • Osteoblasts 13%
  • Osteogenesis 12%
  • Osteonectin 10%
  2 Citations (Scopus)

  214 Downloads (Pure)

• Mesothelial cells and peritoneal homeostasis

  Mutsaers, S. E., Prele, C., Pengelly, S. & Herrick, S. E., 1 Oct 2016, In: Fertility and Sterility. 106, 5, p. 1018-1024 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Homeostasis 100%
  • Epithelium 83%
  • Serous Membrane 36%
  • Cell Physiological Phenomena 34%
  • Intraperitoneal Injections 26%
  60 Citations (Scopus)

• Mesothelial cells and pleural immunology (Textbook Chapter)

  Mutsaers, S. E., Jaurand, M. C. C., Lee, G. C. & Prele, C. M., 2016, Textbook of Pleural Diseases. R. W. L. . G. L. (ed.). United States, Vol. CRC Press Talyor & Francis.

  Research output: Chapter in Book/Conference paper › Other chapter contribution

• Structure and function of the mesothelial cell

  Mutsaers, S., Prêle, C. M. A. & Herrick, S. E., 2016, Intraperitoneal Cancer Therapy: Principles and Practice. Ceelen, W. P. & Levine, E. A. (eds.). CRC Press, p. 9-25 17 p.

  Research output: Chapter in Book/Conference paper › Chapter › peer-review
• 2015

  BARD1 mediates TGF-β signaling in pulmonary fibrosis

  André, P. A., Prele, C., Vierkotten, S., Carnesecchi, S., Donati, Y., Chambers, R. C., Pache, J. C., Crestani, B., Barazzone-Argiroffo, C., Königshoff, M., Laurent, G. & Irminger-Finger, I., 29 Sep 2015, In: Respiratory Research. 16, 1, p. 1-14 14 p., 118.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pulmonary Fibrosis 100%
  • Lung 46%
  • Idiopathic Pulmonary Fibrosis 41%
  • Fibrosis 38%
  • Protein Isoforms 28%
  20 Citations (Web of Science)

• Loss of miR-223 and JNK signaling contribute to elevated stathmin in malignant pleural mesothelioma

  Birnie, K. A., Yip, Y. Y., Ng, D. C. H., Kirschner, M. B., Reid, G., Prêle, C., Musk, A., Lee, G., Thompson, P., Mutsaers, S. & Badrian, B., 2015, In: Molecular Cancer Research. 13, 7, p. 1106-1118

  Research output: Contribution to journal › Article › peer-review

  • Stathmin 100%
  • Malignant Mesothelioma 78%
  • JNK Mitogen-Activated Protein Kinases 72%
  • Cell Movement 10%
  • Cell Line 10%
  34 Citations (Scopus)

• Mesothelial cells in tissue repair and fibrosis

  Mutsaers, S. E., Birnie, K., Lansley, S., Herrick, S. E., Lim, C. B. & Prele, C., 2015, In: Frontiers in Pharmacology. 6, 113.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Fibrosis 100%
  • Cell Tracking 27%
  • Fibrinolysis 21%
  • Epithelial-Mesenchymal Transition 19%
  • Homeostasis 14%
  105 Citations (Scopus)

  244 Downloads (Pure)

• Mitochondria-derived reactive oxygen species drive GANT61-induced mesothelioma cell apoptosis

  Lim, C. B., Prêle, C., Baltic, S., Arthur, P., Creaney, J., Neil Watkins, D., Thompson, P. & Mutsaers, S., 16 Jan 2015, In: Oncotarget. 6, 3, p. 1519-1530

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • GANT 61 100%
  • Mesothelioma 64%
  • Mitochondria 44%
  • Reactive Oxygen Species 43%
  • Apoptosis 33%
  26 Citations (Scopus)

  181 Downloads (Pure)
• 2014

  Fibulin-1 predicts disease progression in patients with idiopathic pulmonary fibrosis

  Jaffar, J., Unger, S., Corte, T. J., Keller, M., Wolters, P. J., Richeldi, L., Cerri, S., Prele, C., Hansbro, P., Argraves, W. S., Oliver, R. A., Oliver, B. G., Black, J. L. & Burgess, J. K., Oct 2014, In: Chest. 146, 4, p. 1055-1063

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • fibulin 100%
  • Idiopathic Pulmonary Fibrosis 75%
  • Disease Progression 50%
  • Lung 23%
  • Fibroblasts 14%
  28 Citations (Scopus)

• Harnessing the potential of lung stem cells for regenerative medicine

  Mcqualter, J. L., Anthony, D. A., Bozinovski, S., Prêle, C. & Laurent, G., 2014, In: International Journal of Biochemistry and Cell Biology. 56, p. 82-91

  Research output: Contribution to journal › Article › peer-review

  • Irritant 100%
  • Allergen 84%
  • Smoke 77%
  • Regenerative Medicine 75%
  • Stem Cells 50%
  12 Citations (Scopus)
• 2013

  Mutational Analysis of Hedgehog Signaling Pathway Genes in Human Malignant Mesothelioma

  Lim, C. B., Prêle, C., Cheah, H., Cheng, Y. Y., Klebe, S., Reid, G., Watkins, D. N., Baltic, S., Thompson, P. & Mutsaers, S., 2013, In: PLoS One. 8, 6, p. 12pp

  Research output: Contribution to journal › Article › peer-review

  Open Access
  23 Citations (Scopus)
• 2012

  Genetic partitioning of interleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis

  O'Donoghue, R. J. J., Knight, D. A., Richards, C. D., Prele, C., Lau, H., Jarnicki, A. G., Jones, J., Bozinovski, S., Vlahos, R., Thiem, S., Mckenzie, B. S., Wang, B., Stumbles, P., Laurent, G. J., Mcanulty, R. J., Rose-John, S., Zhu, H. J., Anderson, G. P., Ernst, M. R. & Mutsaers, S., 2012, In: EMBO Molecular Medicine. 4, 9, p. 939-951

  Research output: Contribution to journal › Article › peer-review

  Open Access
  88 Citations (Scopus)

• Insulin-like growth factor-1 overexpression in cardiomyocytes diminishes ex vivo heart functional recovery after acute ischemia

  Prele, C., Reichelt, M. E., Mutsaers, S., Davies, M., Delbridge, L. M., Headrick, J. P., Rosenthal, N., Bogoyevitch, M. A. & Grounds, M., 2012, In: Cardiovascular Pathology. 21, p. 17-27

  Research output: Contribution to journal › Article › peer-review
  16 Citations (Scopus)

• STAT3: A central mediator of pulmonary fibrosis?

  Prele, C., Yao, E., O'Donoghue, R. J. J., Mutsaers, S. E. & Knight, D. A., 15 Jul 2012, Proceedings of the American Thoracic Society. Laurent, G. J. (ed.). 3 ed. United States: American Thoracic Society, Vol. 9. p. 177-182 6 p.

  Research output: Chapter in Book/Conference paper › Conference paper › peer-review

  • Pulmonary Fibrosis 100%
  • Idiopathic Pulmonary Fibrosis 69%
  • Fibrosis 64%
  • Wound Healing 50%
  • Lung Diseases 25%
  40 Citations (Scopus)

• STAT3-mediated signaling dysregulates lung fibroblast-myofibroblast activation and differentiation in UIP/IPF

  Pechkovsky, D., Prele, C., Wong, J., Hogaboam, C. M., Mcanulty, R. J., Laurent, G., Zhang, S. M., Selman, M., Mutsaers, S. & Knight, D. A., 2012, In: The American Journal of Pathology. 180, 4, p. 1398-1412

  Research output: Contribution to journal › Article › peer-review
  80 Citations (Scopus)

• The anti-inflammatory actions of IL-4 in human monocytes are not mediated by IL-10, RP105 or the kinase activity of RIPK2

  Woodward, E., Kolesnik, T. B., Nicholson, S. E., Prele, C. & Hart, P., 2012, In: Cytokine. 58, 3, p. 415-423

  Research output: Contribution to journal › Article › peer-review
  12 Citations (Scopus)
• 2011

  Mesothelial Cell Differention into Osteoblast- and Adipocyte-Like Cells

  Lansley, S., Searles, R. G., Hoi, A., Thomas, C., Moneta, H., Herrick, S. E., Thompson, P., Newman, M., Sterrett, G., Prele, C. & Mutsaers, S., 2011, In: Journal of Cellular and Molecular Medicine. 15, 10, p. 2095-2105

  Research output: Contribution to journal › Article › peer-review
  51 Citations (Scopus)

• STAT3 in tissue fibrosis: Is there a role in the lung?

  Knight, D., Mutsaers, S. & Prêle, C., 2011, In: Pulmonary Pharmacology and Therapeutics. 24, p. 193-198

  Research output: Contribution to journal › Article › peer-review
  42 Citations (Scopus)
• 2010

  The anti-inflammatory effects of interleukin-4 are not mediated by suppressor of cytokine signalling-1 (SOCS1)

  Woodward, E., Prele, C., Nicholson, S. E., Kolesnik, T. B. & Hart, P., 2010, In: Immunology. 131, 1, p. 118-127

  Research output: Contribution to journal › Article › peer-review
  33 Citations (Scopus)
• 2009

  SOCS1 regulates the IFN but not NFκB pathway in TLR-stimulated human monocytes and macrophages

  Prêle, C. M., Woodward, E. A., Bisley, J., Keith-Magee, A., Nicholson, S. E. & Hart, P. H., 1 Dec 2009, In: Journal of Immunology. 181, 11, p. 8018-8026 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Monocytes 100%
  • Macrophages 84%
  • Messenger RNA 22%
  • Synovial Fluid 22%
  • Orthomyxoviridae 20%
  40 Citations (Scopus)
• 2008

  SOCS1 Regulates the IFN but Not NF{kappa}B Pathway in TLR-Stimulated Human Monocytes and Macrophages

  Prele, C., Woodward, E. A., Bisley, J., Keith-Magee, A., Nicholson, S. E. & Hart, P., 2008, In: Journal of Immunology. 181, 11, p. 8018-8026

  Research output: Contribution to journal › Article › peer-review

  • NF-kappa B 100%
  • Monocytes 77%
  • Macrophages 65%
  • Messenger RNA 17%
  • Synovial Fluid 17%

• SOCS1 regulates the IFN but not NFkappaB pathway in TLR-stimulated human monocytes and macrophages

  Prele, C., Woodward, E., Bisely, J., Keith-Magee, A., Nicholson, S. & Hart, P., 2008, In: The Journal of Immunology. 181

  Research output: Contribution to journal › Article › peer-review
• 2007

  Activated signal transducer and activator of transcription-3 (STAT3) is a poor regulator of tumour necrosis factor-α production by human monocytes

  Prele, C., Keith-Magee, A. L., Murcha, M. & Hart, P., 2007, In: Clinical and Experimental Immunology. 147, 3, p. 564-572

  Research output: Contribution to journal › Article › peer-review

  • human TNF protein 100%
  • STAT3 Transcription Factor 88%
  • Monocytes 60%
  • Lipopolysaccharides 25%
  • Interleukin-10 19%
  14 Citations (Scopus)

• The origin of regenerating mesothelium: a historical perspective

  Mutsaers, S. E., Prêle, C. M., Lansley, S. M. & Herrick, S. E., Jun 2007, In: The International Journal of Artificial Organs. 30, 6, p. 484-494 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Epithelium 100%
  • Wounds and Injuries 47%
  • Mesoderm 35%
  • Regeneration 27%
  • Cell Movement 26%
  20 Citations (Scopus)
• 2006

  Suppressor of cytokine signalling-3 at pathological levels does not regulate lipopolysaccharide or interleukin-10 control of tumour necrosis factor-α production by human monocytes

  Prele, C., Keith-Magee, A. L., Yerkovich, S. T., Murcha, M. & Hart, P., 2006, In: Immunology. 119, 1, p. 8-17

  Research output: Contribution to journal › Article › peer-review

  • human TNF protein 100%
  • Interleukin-10 65%
  • Lipopolysaccharides 62%
  • Monocytes 60%
  • Cytokines 45%
  14 Citations (Scopus)

• The receptor for cis-urocanic acid remains elusive

  Woodward, E., Prele, C., Finlay-Jones, J. & Hart, P., 2006, In: Journal of Investigative Dermatology. 126, 5, p. 1191-1193

  Research output: Contribution to journal › Letter
  14 Citations (Scopus)