Research output per year
Research output per year
Personal profile
Biography
Associate Professor Cecilia Prêle is a Principal Research Fellow within the School of Biomedical Sciences at the University of Western Australia. She was awarded her PhD in Biochemistry from University College London, UK in 2001. After completing a short postdoctoral position at Guy’s, St Thomas’ and Kings College London she relocated to Perth. Her research focuses on investigating signal transduction pathways activated in disease and on how these modified pathways contribute to the initiation and progression of disease. Her research is part of a larger collaborative program of research, which aims to investigate the mechanisms driving lung tissue repair and regeneration.
Research
• Molecular mechanisms underlying lung fibrosis
• Mechanisms regulating lung repair and regeneration
• Multi-potential nature of mesothelial cells and serosal repair
• Mechanisms regulating lung repair and regeneration
• Multi-potential nature of mesothelial cells and serosal repair
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research expertise keywords
- Molecular biology
- Inflammation
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- 6 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Emerging role of immune cells as drivers of pulmonary fibrosis
Mutsaers, S. E., Miles, T., Prêle, C. M. & Hoyne, G. F., Dec 2023, In: Pharmacology & Therapeutics. 252, 13 p., 108562.Research output: Contribution to journal › Review article › peer-review
18 Citations (Scopus) -
Idiopathic Pulmonary Fibrosis Is Associated with Common Genetic Variants and Limited Rare Variants
NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Peljto, A. L., Blumhagen, R. Z., Walts, A. D., Cardwell, J., Powers, J., Corte, T. J., Dickinson, J. L., Glaspole, I., Moodley, Y. P., Vasakova, M. K., Bendstrup, E., Davidsen, J. R., Borie, R., Crestani, B., Dieude, P., Bonella, F., Costabel, U., Gudmundsson, G. & Donnelly, S. C. & 96 others, , 1 May 2023, In: American Journal of Respiratory and Critical Care Medicine. 207, 9, p. 1194-1202 9 p.Research output: Contribution to journal › Article › peer-review
Open Access34 Citations (Scopus) -
Using RNA-seq to identify suitable housekeeping genes for hypoxia studies in human adipose-derived stem cells
Ong, H. T., Prêle, C. M. & Dilley, R. J., Dec 2023, In: BMC Molecular and Cell Biology. 24, 1, 15 p., 16.Research output: Contribution to journal › Article › peer-review
Open Access -
Using x-ray micro computed tomography to quantify intracochlear fibrosis after cochlear implantation in a Guinea pig model
Braack, K., Miles, T., Amat, F., Brown, D., Atlas, M., Kuthubutheen, J., Mulders, W. & Prêle, C. M. A., Sept 2023, In: Heliyon. 9, 9, e19343.Research output: Contribution to journal › Article › peer-review
Open Access -
Plasma cell but not CD20-mediated B cell depletion protects from bleomycin-induced lung fibrosis
Prêle, C. M., Miles, T., Pearce, D. R., O'Donoghue, R. J., Grainge, C., Barrett, L., Birnie, K., Lucas, A. D., Baltic, S., Ernst, M., Rinaldi, C., Laurent, G. J., Knight, D. A., Fear, M., Hoyne, G., McAnulty, R. J. & Mutsaers, S. E., 1 Nov 2022, In: The European Respiratory Journal. 60, 5, 2101469.Research output: Contribution to journal › Article › peer-review
Open AccessFile33 Citations (Scopus)66 Downloads (Pure)
Datasets
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Additional file 2 of Using RNA-seq to identify suitable housekeeping genes for hypoxia studies in human adipose-derived stem cells
Ong, H. T. (Creator), Prêle, C. M. (Creator) & Dilley, R. J. (Creator), Figshare, 13 Aug 2024
DOI: 10.6084/m9.figshare.26582642, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_Using_RNA-seq_to_identify_suitable_housekeeping_genes_for_hypoxia_studies_in_human_adipose-derived_stem_cells/26582642
Dataset
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Additional file 3 of Using RNA-seq to identify suitable housekeeping genes for hypoxia studies in human adipose-derived stem cells
Ong, H. T. (Creator), Prêle, C. M. (Creator) & Dilley, R. J. (Creator), Figshare, 13 Aug 2024
DOI: 10.6084/m9.figshare.26582645, https://springernature.figshare.com/articles/dataset/Additional_file_3_of_Using_RNA-seq_to_identify_suitable_housekeeping_genes_for_hypoxia_studies_in_human_adipose-derived_stem_cells/26582645
Dataset
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Additional file 2 of Using RNA-seq to identify suitable housekeeping genes for hypoxia studies in human adipose-derived stem cells
Ong, H. T. (Creator), Prêle, C. M. (Creator) & Dilley, R. J. (Creator), Figshare, 13 Aug 2024
DOI: 10.6084/m9.figshare.26582642.v1, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_Using_RNA-seq_to_identify_suitable_housekeeping_genes_for_hypoxia_studies_in_human_adipose-derived_stem_cells/26582642/1
Dataset
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Additional file 3 of Using RNA-seq to identify suitable housekeeping genes for hypoxia studies in human adipose-derived stem cells
Ong, H. T. (Creator), Prêle, C. M. (Creator) & Dilley, R. J. (Creator), Figshare, 13 Aug 2024
DOI: 10.6084/m9.figshare.26582645.v1, https://springernature.figshare.com/articles/dataset/Additional_file_3_of_Using_RNA-seq_to_identify_suitable_housekeeping_genes_for_hypoxia_studies_in_human_adipose-derived_stem_cells/26582645/1
Dataset
Projects
- 6 Finished
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2018 - Cell Insight CX7 High Content System
Yeoh, G. (Investigator 01), Forrest, A. (Investigator 02), Ganss, R. (Investigator 03), Blancafort, P. (Investigator 04), Swaminatha Iyer, I. (Investigator 05), Pavlos, N. (Investigator 06), Xu, J. (Investigator 07), Kirkham, L.-A. (Investigator 08), Dwivedi, G. (Investigator 09), Ingley, E. (Investigator 10), Davern, K. (Investigator 11), Kahler, C. (Investigator 12), Meehan, K. (Investigator 13), Lesterhuis, W. (Investigator 14), Hamzah, J. (Investigator 15), Prele, C. (Investigator 16) & Mutsaers, S. (Investigator 17)
NHMRC National Health and Medical Research Council
1/01/19 → 31/12/19
Project: Research
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Project Grant - tRNA fragments: novel diagnostic and functional targets for malignant mesothelioma
Mutsaers, S. (Investigator 01), Birnie, K. (Investigator 02), Prele, C. (Investigator 03), De Klerk, N. (Investigator 04), Musk, A. (Investigator 05) & Lansley, S. (Investigator 06)
1/01/19 → 31/12/19
Project: Research
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Merit Award - Projects - BARD1, a key mediator of TGF beta signalling and telomere maintenance in lung fibrosis
Prele, C. (Investigator 01)
Department of Health (Western Australia)
1/07/17 → 30/06/18
Project: Research
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Epithelial-Mesenchymal cell communication; towards new therapeutic targets for fibrosis
Prele, C. (Investigator 01), Knight, D. (Investigator 02), Fear, M. (Investigator 03), McAnulty, R. (Investigator 04) & Wood, F. (Investigator 05)
NHMRC National Health and Medical Research Council
1/01/17 → 31/08/21
Project: Research
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STAT3 Regulation of Cell Responses in IPF
Prele, C. (Investigator 01), Mutsaers, S. (Investigator 02), Knight, D. (Investigator 03), O'Donoghue, R. (Investigator 04), Hoyne, G. (Investigator 05) & Laurent, G. (Investigator 06)
NHMRC National Health and Medical Research Council
1/01/14 → 31/12/17
Project: Research