Research output per year
Research output per year
Personal profile
Biography
Associate Professor Cecilia Prêle is a Principal Research Fellow within the School of Biomedical Sciences at the University of Western Australia. She was awarded her PhD in Biochemistry from University College London, UK in 2001. After completing a short postdoctoral position at Guy’s, St Thomas’ and Kings College London she relocated to Perth. Her research focuses on investigating signal transduction pathways activated in disease and on how these modified pathways contribute to the initiation and progression of disease. Her research is part of a larger collaborative program of research, which aims to investigate the mechanisms driving lung tissue repair and regeneration.
Research
• Molecular mechanisms underlying lung fibrosis
• Mechanisms regulating lung repair and regeneration
• Multi-potential nature of mesothelial cells and serosal repair
• Mechanisms regulating lung repair and regeneration
• Multi-potential nature of mesothelial cells and serosal repair
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research expertise keywords
- Molecular biology
- Inflammation
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Emerging role of immune cells as drivers of pulmonary fibrosis
Mutsaers, S. E., Miles, T., Prêle, C. M. & Hoyne, G. F., Dec 2023, In: Pharmacology & Therapeutics. 252, 13 p., 108562.Research output: Contribution to journal › Review article › peer-review
7 Citations (Scopus) -
Idiopathic Pulmonary Fibrosis Is Associated with Common Genetic Variants and Limited Rare Variants
NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Peljto, A. L., Blumhagen, R. Z., Walts, A. D., Cardwell, J., Powers, J., Corte, T. J., Dickinson, J. L., Glaspole, I., Moodley, Y. P., Vasakova, M. K., Bendstrup, E., Davidsen, J. R., Borie, R., Crestani, B., Dieude, P., Bonella, F., Costabel, U., Gudmundsson, G., Donnelly, S. C., & 96 others, 1 May 2023, In: American Journal of Respiratory and Critical Care Medicine. 207, 9, p. 1194-1202 9 p.Research output: Contribution to journal › Article › peer-review
Open Access23 Citations (Scopus) -
Using RNA-seq to identify suitable housekeeping genes for hypoxia studies in human adipose-derived stem cells
Ong, H. T., Prêle, C. M. & Dilley, R. J., Dec 2023, In: BMC Molecular and Cell Biology. 24, 1, 15 p., 16.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Web of Science) -
Using x-ray micro computed tomography to quantify intracochlear fibrosis after cochlear implantation in a Guinea pig model
Braack, K., Miles, T., Amat, F., Brown, D., Atlas, M., Kuthubutheen, J., Mulders, W. & Prêle, C. M. A., Sept 2023, In: Heliyon. 9, 9, e19343.Research output: Contribution to journal › Article › peer-review
Open Access -
Plasma cell but not CD20-mediated B cell depletion protects from bleomycin-induced lung fibrosis
Prêle, C. M., Miles, T., Pearce, D. R., O'Donoghue, R. J., Grainge, C., Barrett, L., Birnie, K., Lucas, A. D., Baltic, S., Ernst, M., Rinaldi, C., Laurent, G. J., Knight, D. A., Fear, M., Hoyne, G., McAnulty, R. J. & Mutsaers, S. E., 1 Nov 2022, In: The European Respiratory Journal. 60, 5, 2101469.Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Citations (Scopus)52 Downloads (Pure)
Datasets
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Additional file 2 of Using RNA-seq to identify suitable housekeeping genes for hypoxia studies in human adipose-derived stem cells
Ong, T. (Creator), Prele, C. (Creator) & Dilley, R. (Creator), Figshare, 13 Aug 2024
DOI: 10.6084/m9.figshare.26582642.v1, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_Using_RNA-seq_to_identify_suitable_housekeeping_genes_for_hypoxia_studies_in_human_adipose-derived_stem_cells/26582642/1
Dataset
Projects
- 6 Finished
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Project Grant - tRNA fragments: novel diagnostic and functional targets for malignant mesothelioma
Mutsaers, S., Birnie, K., Prele, C., De Klerk, N., Musk, A. & Lansley, S.
1/01/19 → 31/12/19
Project: Research
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2018 - Cell Insight CX7 High Content System
Yeoh, G., Forrest, A., Ganss, R., Blancafort, P., Swaminatha Iyer, K., Pavlos, N., Xu, J., Kirkham, L., Dwivedi, G., Ingley, E., Davern, K., Kahler, C., Meehan, K., Lesterhuis, W., Hamzah, J., Prele, C. & Mutsaers, S.
NHMRC National Health and Medical Research Council
1/01/19 → 31/12/19
Project: Research
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Epithelial-Mesenchymal cell communication; towards new therapeutic targets for fibrosis
Prele, C., Knight, D., Fear, M., McAnulty, R. & Wood, F.
NHMRC National Health and Medical Research Council
1/01/17 → 31/08/21
Project: Research
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STAT3 Regulation of Cell Responses in IPF
Prele, C., Mutsaers, S., Knight, D., O'Donoghue, R., Hoyne, G. & Laurent, G.
NHMRC National Health and Medical Research Council
1/01/14 → 31/12/17
Project: Research