Cecilia Prele

Associate Professor, PhD Coll.Lond.

  • The University of Western Australia (M503), 35 Stirling Highway,

    6009 Perth

    Australia

  • 771 Citations
  • 16 h-Index
20022020
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Personal profile

Biography

Associate Professor Cecilia Prêle is a Senior Research Fellow and Administrative Director for the Centre for Cell Therapy and Regenerative Medicine (CCTRM), University of Western Australia and is a Senior Research Scientist within the Centre for Respiratory Health, UWA. She was awarded her PhD in Biochemistry from University College London, UK in 2001. After completing a short postdoctoral position at Guy’s, St Thomas’ and Kings College London she relocated to Perth. Her research focuses on investigating signal transduction pathways activated in disease and on how these modified pathways contribute to the initiation and progression of disease. Her research is part of a larger collaborative program of research, which aims to investigate the mechanisms driving lung tissue repair and regeneration.

Research

• Molecular mechanisms underlying lung fibrosis
• Mechanisms regulating lung repair and regeneration
• Multi-potential nature of mesothelial cells and serosal repair

Keywords

  • Molecular biology
  • Inflammation

Fingerprint Dive into the research topics where Cecilia Prele is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 17 Similar Profiles
Idiopathic Pulmonary Fibrosis Medicine & Life Sciences
Lung Medicine & Life Sciences
STAT3 Transcription Factor Medicine & Life Sciences
Fibroblasts Medicine & Life Sciences
Pulmonary Fibrosis Medicine & Life Sciences
Monocytes Medicine & Life Sciences
Mesothelioma Medicine & Life Sciences
Fibrosis Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2002 2019

1 Citation (Scopus)

Ephrin-A2 affects wound healing and scarring in a murine model of excisional injury

Wijeratne, D., Rodger, J., Stevenson, A., Wallace, H., Prêle, C. M., Wood, F. M. & Fear, M. W., May 2019, In : Burns. 45, 3, p. 682-690 9 p.

Research output: Contribution to journalArticle

Ephrin-A2
Ephrins
Ephrin-A5
Wound Healing
Cicatrix
1 Citation (Scopus)

Inhibition of collagen production delays malignant mesothelioma tumor growth in a murine model

Abayasiriwardana, K. S., Wood, M. K., Prêle, C. M., Birnie, K. A., Robinson, B. W., Laurent, G. J., McAnulty, R. J. & Mutsaers, S. E., 5 Mar 2019, In : Biochemical and Biophysical Research Communications. 510, 2, p. 198-204 7 p.

Research output: Contribution to journalArticle

Tumors
Collagen
Mesothelioma
Growth
Neoplasms

MicroRNA Signatures in Malignant Pleural Mesothelioma Effusions

Birnie, K. A., Prele, C. M., Musk, A. W. B., de Klerk, N., Lee, Y. C. G., Fitzgerald, D., Allcock, R. J. N., Thompson, P. J., Creaney, J., Badrian, B. & Mutsaers, S. E., 31 Jul 2019, In : Disease Markers. 9 p., 8628612.

Research output: Contribution to journalArticle

Open Access
Malignant Pleural Effusion
Pleural Effusion
MicroRNAs
Biomarkers
Cytology
2 Citations (Scopus)
Idiopathic Pulmonary Fibrosis
Cell Aging
Genes
Alleles
Genome-Wide Association Study
3 Citations (Scopus)
165 Downloads (Pure)

STAT3 regulates the onset of oxidant-induced senescence in lung fibroblasts

Waters, D. W., Blokland, K. E. C., Pathinayake, P. S., Wei, L., Schuliga, M., Jaffar, J., Westall, G. P., Hansbro, P. M., Prele, C. M., Mutsaers, S. E., Bartlett, N. W., Burgess, J. K., Grainge, C. L. & Knight, D. A., Jul 2019, In : American Journal of Respiratory Cell and Molecular Biology.

Research output: Contribution to journalArticle

Open Access
File
STAT3 Transcription Factor
Fibroblasts
Oxidants
Lung
Chemical activation

Projects 2004 2020