Carolyn Grove

Dr

  • The University of Western Australia (M504), 35 Stirling Highway,

    6009 Perth

    Australia

  • 106 Citations
  • 5 h-Index
20152021
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Research Output 2015 2019

  • 106 Citations
  • 5 h-Index
  • 8 Article
  • 2 Letter
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Article
2019
3 Citations (Scopus)

PiggyBac transposon tools for recessive screening identify B-cell lymphoma drivers in mice

Weber, J., de la Rosa, J., Grove, C. S., Schick, M., Rad, L., Baranov, O., Strong, A., Pfaus, A., Friedrich, M. J., Engleitner, T., Lersch, R., Öllinger, R., Grau, M., Menendez, I. G., Martella, M., Kohlhofer, U., Banerjee, R., Turchaninova, M. A., Scherger, A., Hoffman, G. J. & 21 othersHess, J., Kuhn, L. B., Ammon, T., Kim, J., Schneider, G., Unger, K., Zimber-Strobl, U., Heikenwälder, M., Schmidt-Supprian, M., Yang, F., Saur, D., Liu, P., Steiger, K., Chudakov, D. M., Lenz, G., Quintanilla-Martinez, L., Keller, U., Vassiliou, G. S., Cadiñanos, J., Bradley, A. & Rad, R., 1 Dec 2019, In : Nature Communications. 10, 1, 1415.

Research output: Contribution to journalArticle

Open Access
B-Cell Lymphoma
genes
mice
Screening
chromatin
Fibrosis
Blood Platelets
Bone Marrow
Neoplasms
Megakaryocytes
2017
20 Citations (Scopus)

Molecular synergy underlies the co-occurrence patterns and phenotype of NPM1-mutant acute myeloid leukemia

Dovey, O. M., Cooper, J. L., Mupo, A., Grove, C. S., Lynn, C., Conte, N., Andrews, R. M., Pacharne, S., Tzelepis, K., Vijayabaskar, M. S., Green, P., Rad, R., Arends, M., Wright, P., Yusa, K., Bradley, A., Varela, I. & Vassiliou, G. S., 26 Oct 2017, In : Blood. 130, 17, p. 1911-1922 12 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Genes
Phenotype
Mutation
Gene expression
7 Citations (Scopus)

Preventing chemotherapy-induced myelosuppression by repurposing the FLT3 inhibitor quizartinib

Taylor, S., Duyvestyn, J., Zeps, S., Dishington, E., Rinaldi, C., Dovey, O. M., Vassiliou, G., Grove, C. & Langdon, W., 9 Aug 2017, In : Science Translational Medicine. 9, 14 p., aam8060.

Research output: Contribution to journalArticle

Drug Therapy
gemcitabine
Fluorouracil
Bone Marrow
Neoplasms
Open Access
Waldenstrom Macroglobulinemia
mutations
therapy
Cells
Testing
2016
23 Citations (Scopus)

Development and validation of a comprehensive genomic diagnostic tool for myeloid malignancies

Mckerrell, T., Moreno, T., Ponstingl, H., Bolli, N., Dias, J. M. L., Tischler, G., Colonna, V., Manasse, B., Bench, A., Bloxham, D., Herman, B., Fletcher, D., Park, N., Quail, M. A., Manes, N., Hodkinson, C., Baxter, J., Sierra, J., Foukaneli, T., Warren, A. J. & 12 othersChi, J., Costeas, P., Rad, R., Huntly, B., Grove, C., Ning, Z., Tyler-Smith, C., Varela, I., Scott, M., Nomdedeu, J., Mustonen, V. & Vassiliou, G. S., 2016, In : Blood. 128, 1, p. E1-E9

Research output: Contribution to journalArticle

Open Access
Blood
Genes
Mutation
Leukemia
Neoplasms
43 Citations (Scopus)

Targeting chromatin regulators inhibits leukemogenic gene expression in NPM1 mutant leukemia

Kühn, M. W. M., Song, E., Feng, Z., Sinha, A., Chen, C. W., Deshpande, A. J., Cusan, M., Farnoud, N., Mupo, A., Grove, C., Koche, R., Bradner, J. E., De Stanchina, E., Vassiliou, G. S., Hoshii, T. & Armstrong, S. A., 2016, In : Cancer Discovery. 6, 10, p. 1166-1181

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Chromatin
Leukemia
Homeobox Genes
Gene Expression
2015
5 Citations (Scopus)
320 Downloads (Pure)

Loss of c-Cbl E3 ubiquitin ligase activity enhances the development of myeloid leukemia in FLT3-ITD mutant mice

Taylor, S., Thien, C., Dagger, S., Duyvestyn, J., Grove, C., Lee, B. H., Gilliland, D. G. & Langdon, W., 2015, In : Experimental Hematology. 43, 3, p. 191-206

Research output: Contribution to journalArticle

Open Access
File
fms-Like Tyrosine Kinase 3
Myeloid Leukemia
Ubiquitin-Protein Ligases
STAT5 Transcription Factor
Mutation