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Carla Mellough

Ms, PhD

 https://orcid.org/0000-0003-3685-6516

  • The University of Western Australia (M517), 35 Stirling Highway,

    6009 Perth

    Australia

  • 372 Citations
  • 9 h-Index
20042019
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  • 11 Similar Profiles
Pluripotent Stem Cells Medicine & Life Sciences
Induced Pluripotent Stem Cells Medicine & Life Sciences
Retina Medicine & Life Sciences
Vertebrate Photoreceptor Cells Medicine & Life Sciences
Retinal Ganglion Cells Medicine & Life Sciences
Organoids Medicine & Life Sciences
Retinitis Pigmentosa Medicine & Life Sciences
Stem cells Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2004 2019

4 Citations (Scopus)

An integrated transcriptional analysis of the developing human retina

Mellough, C. B., Bauer, R., Collin, J., Dorgau, B., Zerti, D., Dolan, D. W. P., Jones, C. M., Izuogu, O. G., Yu, M., Hallam, D., Steyn, J. S., Whites, K., Steel, D. H., Santibanez-Koref, M., Elliott, D. J., Jackson, M. S., Lindsay, S., Grellscheid, S. & Lako, M., 15 Jan 2019, In : Development. 146, 2, 16 p., 169474.

Research output: Contribution to journal › Article

Open Access
1 Citation (Scopus)

Systematic Comparison of Retinal Organoid Differentiation from Human Pluripotent Stem Cells Reveals Stage Specific, Cell Line, and Methodological Differences

Mellough, C. B., Collin, J., Queen, R., Hilgen, G., Dorgau, B., Zerti, D., Felemban, M., White, K., Sernagor, E. & Lako, M., Jul 2019, In : Stem Cells Translational Medicine. 8, 7, p. 694-706

Research output: Contribution to journal › Article

Open Access
Organoids
Embryoid Bodies
Pluripotent Stem Cells
Cell Line
Maintenance

3D retina organoids produced from CRX-GFP human embryonic stem cells (hESCs) processed into retinal sheets and transplanted into immunodeficient retinal degenerate (RD) rats

Seiler, M. J., McLelland, B. T., Collin, J., Mellough, C. B., Lako, M., Aramant, R. B., Nistor, G. & Keirstead, H. S., Jul 2018, In : Investigative ophthalmology & visual science. 59, 9, 3 p., 544.

Research output: Contribution to journal › Abstract/Meeting Abstract

7 Citations (Scopus)

Analysis of human ES cell differentiation establishes that the dominant isoforms of the lncRNAs RMST and FIRRE are circular

Izuogu, O. G., Alhasan, A. A., Mellough, C., Collin, J., Gallon, R., Hyslop, J., Mastrorosa, F. K., Ehrmann, I., Lako, M., Elliott, D. J., Santibanez-Koref, M. & Jackson, M. S., 20 Apr 2018, In : BMC Genomics. 19, 18 p., 276.

Research output: Contribution to journal › Article

Open Access
2 Citations (Scopus)

Extracellular matrix component expression in human pluripotent stem cell-derived retinal organoids recapitulates retinogenesis in vivo and reveals an important role for IMPG1 and CD44 in the development of photoreceptors and interphotoreceptor matrix

Felemban, M., Dorgau, B., Hunt, N. C., Hallam, D., Zerti, D., Bauer, R., Ding, Y., Collin, J., Steel, D., Krasnogor, N., Al-Aama, J., Lindsay, S., Mellough, C. & Lako, M., 1 Jul 2018, In : Acta Biomaterialia. 74, p. 207-221 15 p.

Research output: Contribution to journal › Article

Open Access
Organoids
Pluripotent Stem Cells
Proteoglycans
Stem cells
Extracellular Matrix

Projects 2018 2018

Utilising patient-specific retinal organoids in vitro to investigate the effects of an SNRNP200 mutation causing early onset retinitis pigmentosa

Mellough, C., Chen, F. & McLenachan, S.

Retina Australia

1/01/18 → 31/12/18

Project: Research