• 24 Citations
  • 3 h-Index
20182020

Research output per year

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Personal profile

Research

Fungi produce secondary metabolites (SMs), which have been a key target for drug discovery over the last half-century. SM production is encoded by biosynthetic gene clusters (BGCs), with the typical fungal genome containing far more BGCs than what is actively produced by the fungi. My project involves developing bioinformatic pipelines for the mining and analysis of BGCs within the genomes of novel Australian fungi, to try and identify new and interesting compounds.

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Research Output

  • 24 Citations
  • 3 h-Index
  • 7 Article
  • 3 Citations (Scopus)

    Comprehensive chemotaxonomic and genomic profiling of a biosynthetically talented Australian fungus, Aspergillus burnettii sp. nov.

    Gilchrist, C. L. M., Lacey, H. J., Vuong, D., Pitt, J. I., Lange, L., Lacey, E., Pilgaard, B., Chooi, Y. H. & Piggott, A. M., Oct 2020, In : Fungal Genetics and Biology. 143, 103435.

    Research output: Contribution to journalArticle

  • CRISPR-Mediated Activation of Biosynthetic Gene Clusters for Bioactive Molecule Discovery in Filamentous Fungi

    Roux, I., Woodcraft, C., Hu, J., Gilchrist, C. L. M. & Chooi, Y-H., 17 Jul 2020, In : ACS Synthetic Biology. 9, 7, p. 1843-1854

    Research output: Contribution to journalArticle

  • 1 Citation (Scopus)

    Victorin, the host-selective cyclic peptide toxin from the oat pathogen Cochliobolus victoriae, is ribosomally encoded

    Kessler, S. C., Zhang, X., McDonald, M. C., Gilchrist, C. L. M., Lin, Z., Rightmyer, A., Solomon, P. S., Gillian Turgeon, B. & Chooi, Y. H., 29 Sep 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 39, p. 24243-24250 8 p.

    Research output: Contribution to journalArticle

  • Discovery and Heterologous Biosynthesis of the Burnettramic Acids: Rare PKS-NRPS-Derived Bolaamphiphilic Pyrrolizidinediones from an Australian Fungus, Aspergillus burnettii

    Li, H., Gilchrist, C. L. M., Lacey, H. J., Crombie, A., Vuong, D., Pitt, J. I., Lacey, E., Chooi, Y. H. & Piggott, A. M., 1 Mar 2019, In : Organic Letters. 21, 5, p. 1287-1291 5 p.

    Research output: Contribution to journalArticle

  • 10 Citations (Scopus)