Bu Yeap

Professor, MB BS Lond., FRACP

  • The University of Western Australia (M704), 35 Stirling Highway,

    6009 Perth

    Australia

  • 3873 Citations
  • 35 h-Index
19972021
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Research Output 1997 2018

2018
Advanced Glycosylation End Products
Bone Remodeling
Hip Fractures
Bone
Glyoxal
1 Citations

Conclusions about testosterone therapy and cardiovascular risk

Anawalt, B. D. & Yeap, B. B., 1 Mar 2018, In : Asian Journal of Andrology. 20, 2, p. 152-153 2 p.

Research output: Contribution to journalEditorial

1 Citations

Dihydrotestosterone and cancer risk

Chan, Y. X. & Yeap, B. B., 1 Jun 2018, In : Current Opinion in Endocrinology, Diabetes and Obesity. 25, 3, p. 209-217 9 p.

Research output: Contribution to journalReview article

Dihydrotestosterone
Androgens
Prostatic Neoplasms
Neoplasms
Research
2 Citations

Hearing loss and the risk of dementia in later life

Ford, A. H., Hankey, G. J., Yeap, B. B., Golledge, J., Flicker, L. & Almeida, O. P., 1 Jun 2018, In : Maturitas. 112, p. 1-11 11 p.

Research output: Contribution to journalArticle

Audition
Hearing Loss
Dementia
Hazards
Meta-Analysis
1 Citations

Higher IGFBP3 is associated with increased incidence of colorectal cancer in older men independently of IGF1

Chan, Y. X., Alfonso, H., Chubb, S. A. P., Ho, K. K. Y., Gerard Fegan, P., Hankey, G. J., Golledge, J., Flicker, L. & Yeap, B. B., 1 Feb 2018, In : Clinical Endocrinology. 88, 2, p. 333-340 8 p.

Research output: Contribution to journalArticle

Somatomedins
Colorectal Neoplasms
Incidence
Lung Neoplasms
Neoplasms
1 Citations

Low Free Testosterone and Prostate Cancer Risk: A Collaborative Analysis of 20 Prospective Studies

Watts, E. L. , Appleby, P. N. , Perez-Cornago, A. , Bueno-de-Mesquita, H. B. , Chan, J. M. , Chen, C. , Cohn, B. A. , Cook, M. B. , Flicker, L. , Freedman, N. D. , Giles, G. G. , Giovannucci, E. , Gislefoss, R. E. , Hankey, G. J. , Kaaks, R. , Knekt, P. , Kolonel, L. N. , Kubo, T. , Le Marchand, L. , Luben, R. N. & 25 others Luostarinen, T., Männistö, S., Metter, E. J., Mikami, K., Milne, R. L., Ozasa, K., Platz, E. A., Quirós, J. R., Rissanen, H., Sawada, N., Stampfer, M., Stanczyk, F. Z., Stattin, P., Tamakoshi, A., Tangen, C. M., Thompson, I. M., Tsilidis, K. K., Tsugane, S., Ursin, G., Vatten, L., Weiss, N. S., Yeap, B. B., Allen, N. E., Key, T. J. & Travis, R. C., Nov 2018, In : European Urology. 74, 5, p. 595-596

Research output: Contribution to journalArticle

Open Access
Testosterone
Prostatic Neoplasms
Prospective Studies
Odds Ratio
Confidence Intervals
2 Citations
Bipolar Disorder
Dementia
Cardiovascular Diseases
Confidence Intervals
Mortality
Bipolar Disorder
General Hospitals
Morbidity
Health
Men's Health
1 Citations
Open Access
Dihydrotestosterone
Luteinizing Hormone
Testosterone
Sex Hormone-Binding Globulin
Independent Living
1 Citations
Men's Health
Psychotic Disorders
Dementia
Hearing Disorders
Paranoid Schizophrenia
Open Access
File
Insulin-Like Growth Factor Binding Protein 3
Somatomedins
Dementia
Insulin-Like Growth Factor Binding Proteins
Coronary Disease
30 Citations

Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies

Emerging Risk Factors Collaboration/EPIC-CVD/UK Biobank Alcohol Study Group, 14 Apr 2018, In : The Lancet. 391, 10129, p. 1513-1523 11 p.

Research output: Contribution to journalArticle

Open Access
Alcohol Drinking
Prospective Studies
Cardiovascular Diseases
Mortality
Myocardial Infarction
1 Citations

Sex hormones and incident dementia in older men: The health in men study

Ford, A. H., Yeap, B. B., Flicker, L., Hankey, G. J., Chubb, S. A. P., Golledge, J. & Almeida, O. P., 1 Dec 2018, In : Psychoneuroendocrinology. 98, p. 139-147 9 p.

Research output: Contribution to journalArticle

Men's Health
Gonadal Steroid Hormones
Dementia
Testosterone
Confidence Intervals
1 Citations

Subclinical thyroid dysfunction and circulating thyroid hormones are not associated with bone turnover markers or incident hip fracture in older men

Siru, R., Alfonso, H., Chubb, S. A. P., Golledge, J., Flicker, L. & Yeap, B. B., 1 Jul 2018, In : Clinical Endocrinology. 89, 1, p. 93-99 7 p.

Research output: Contribution to journalArticle

Bone Remodeling
Hip Fractures
Thyroid Hormones
Thyrotropin
Thyroid Gland
1 Citations
Bipolar Disorder
Alcohols
Therapeutics
Substance-Related Disorders
Age of Onset
2 Citations

Testosterone and its metabolites: Differential associations with cardiovascular and cerebrovascular events in men

Yeap, B. B., 1 Mar 2018, In : Asian Journal of Andrology. 20, 2, p. 109-114 6 p.

Research output: Contribution to journalReview article

Open Access
Testosterone
Androgens
Dihydrotestosterone
Cardiovascular Diseases
Estradiol

Testosterone treatment in older men: clinical implications and unresolved questions from the Testosterone Trials

Yeap, B. B., Page, S. T. & Grossmann, M., Aug 2018, In : The Lancet Diabetes and Endocrinology. 6, 8, p. 659-672 14 p.

Research output: Contribution to journalReview article

Undercarboxylated osteocalcin: Experimental and human evidence for a role in glucose homeostasis and muscle regulation of insulin sensitivity

Lin, X., Brennan-Speranza, T. C., Levinger, I. & Yeap, B. B., 1 Jul 2018, In : Nutrients. 10, 7, 847

Research output: Contribution to journalReview article

Open Access
osteocalcin
Osteocalcin
G-Protein-Coupled Receptors
insulin resistance
Insulin Resistance

Why is understanding the relationship of testosterone to cardiovascular risk so important?

Yeap, B. B. & Anawalt, B. D., 1 Mar 2018, In : Asian Journal of Andrology. 20, 2, p. 107-108 2 p.

Research output: Contribution to journalEditorial

2017

Body Mass Index and Vascular Disease in Men Aged 65 Years and Over: HIMS (Health In Men Study)

Lacey, B., Yeap, B. B., Golledge, J., Lewington, S., McCaul, K. A., Norman, P. E., Flicker, L., Almeida, O. P. & Hankey, G. J., Dec 2017, In : Journal of the American Heart Association. 6, 12, 19 p., e007343

Research output: Contribution to journalArticle

Open Access
5 Citations

Bone turnover markers: Defining a therapeutic target

Chubb, S. A. P., Byrnes, E., Manning, L., Golledge, J., Ebeling, P. R., Flicker, L., Yeap, B. B. & Vasikaran, S. D., Feb 2017, In : Clinical Biochemistry. 50, 3, p. 162-163 2 p.

Research output: Contribution to journalLetter

1 Citations
Osteocalcin
Type 1 Diabetes Mellitus
Homeostasis
Glucose
Serum
4 Citations
Men's Health
Cohort Studies
Depression
Activities of Daily Living
Exercise Test
8 Citations

Depression as a modifiable factor to decrease the risk of dementia

Almeida, O. P., Hankey, G. J., Yeap, B. B., Golledge, J. & Flicker, L., 2 May 2017, In : Translational Psychiatry. 7, 6 p., e1117

Research output: Contribution to journalArticle

Open Access

Effects of androgen deprivation therapy on telomere length

Cheung, A. S., Yeap, B. B., Hoermann, R., Hui, J., Beilby, J. P. & Grossmann, M., 1 Oct 2017, In : Clinical Endocrinology. 87, 4, p. 381-385 5 p.

Research output: Contribution to journalArticle

Telomere
Androgens
Prostatic Neoplasms
Telomere Shortening
Steroids

Excessive alcohol comsumption increases mortality in later life: a genetic analysis of the health in men cohort study

Almeida, O., Mccaul, K., Hankey, G., Yeap, B., Golledge, J. & Flicker, L., Mar 2017, In : Addiction Biology. 22, 2, p. 570-578

Research output: Contribution to journalArticle

Open Access
File
Men's Health
Cohort Studies
Alcohols
Mortality
Information Storage and Retrieval

Greater physical activity and higher androgen concentrations are independently associated with lower cardiometabolic risk in men

Chasland, L. C., Knuiman, M. W., Divitini, M. L., Chan, Y. X., Handelsman, D. J., Naylor, L. H., Green, D. J. & Yeap, B. B., Nov 2017, In : Clinical Endocrinology. 87, 5, p. 466-474

Research output: Contribution to journalArticle

Open Access
File
Androgens
Exercise
Leisure Activities
Cardiovascular Diseases
Dihydrotestosterone
6 Citations

Higher dihydrotestosterone is associated with the incidence of lung cancer in older men

Chan, Y. X., Alfonso, H., Chubb, P., Handelsman, D. J., Fegan, P. G., Hankey, G. J., Golledge, J., Flicker, L. & Yeap, B. B., Apr 2017, In : Hormones and Cancer. 8, 2, p. 119-126 8 p.

Research output: Contribution to journalArticle

Open Access
File
Dihydrotestosterone
Lung Neoplasms
Gonadal Steroid Hormones
Colorectal Neoplasms
Prostatic Neoplasms
1 Citations

Higher thyrotropin concentration is associated with increased incidence of colorectal cancer in older men

Chan, Y. X., Alfonso, H., Chubb, P., Fegan, P. G., Hankey, G. J., Golledge, J., Flicker, L. & Yeap, B. B., 1 Feb 2017, In : Clinical Endocrinology. 86, 2, p. 278-285 8 p.

Research output: Contribution to journalArticle

Open Access
File
Thyrotropin
Colorectal Neoplasms
Lung Neoplasms
Prostatic Neoplasms
Incidence
1 Citations
Hepcidins
Oral Contraceptives
Interleukin-6
Hormones
Iron
3 Citations

Longevity Klotho gene polymorphism and the risk of dementia in older men

Almeida, O. P., Morar, B., Hankey, G. J., Yeap, B. B., Golledge, J., Jablensky, A. & Flicker, L., 1 Jul 2017, In : Maturitas. 101, p. 1-5 5 p.

Research output: Contribution to journalArticle

Polymorphism
Dementia
Hazards
Genes
Genotype
1 Citations

Lower TSH and higher free thyroxine predict incidence of prostate but not breast, colorectal or lung cancer

Chan, Y. X., Knuiman, M. W., Divitini, M. L., Brown, S. J., Walsh, J. & Yeap, B. B., 1 Oct 2017, In : European Journal of Endocrinology. 177, 4, p. 297-308 12 p.

Research output: Contribution to journalArticle

Thyroxine
Prostate
Colorectal Neoplasms
Lung Neoplasms
Prostatic Neoplasms
7 Citations

Multifaceted interaction of bone, muscle, lifestyle interventions and metabolic and cardiovascular disease: role of osteocalcin

Levinger, I., Brennan-Speranza, T. C., Zulli, A., Parker, L., Lin, X., Lewis, J. R. & Yeap, B. B., 1 Aug 2017, In : Osteoporosis International. 28, 8, p. 2265-2273 9 p.

Research output: Contribution to journalArticle

Osteocalcin
Metabolic Diseases
Life Style
Cardiovascular Diseases
Bone and Bones
1 Citations

Profile of diabetes in men aged 79-97 years: The Western Australian Health in Men Study

Henze, M., Alfonso, H., Flicker, L., George, J., Chubb, P. A. P., Hankey, G. J., Almeida, O. P., Golledge, J., Norman, P. E. & Yeap, B. B., Jun 2017, In : Diabetic Medicine. 34, 6, p. 786-793 8 p.

Research output: Contribution to journalArticle

Men's Health
Health
Odds Ratio
Independent Living
Western Australia
4 Citations
Open Access
Men's Health
Thyrotropin
Thyroxine
Reference Values
Hyperthyroidism
2 Citations

Systolic Blood Pressure and Vascular Disease in Men Aged 65 Years and over the HIMS (Health in Men Study)

Lacey, B., Golledge, J., Yeap, B. B., Lewington, S., McCaul, K. A., Norman, P. E., Flicker, L., Almeida, O. P. & Hankey, G. J., 1 Jun 2017, In : Hypertension. 69, 6, p. 1053-1059 7 p.

Research output: Contribution to journalArticle

Men's Health
Hematologic Diseases
Vascular Diseases
Blood Pressure
Blood Vessels

Testosterone and cardiovascular effects

Yeap, B. B., 1 Apr 2017, Testosterone: From Basic to Clinical Aspects. Hohl, A. (ed.). Springer International Publishing, p. 299-318 20 p.

Research output: Chapter in Book/Conference paperChapter

Testosterone
Androgens
Cardiovascular Diseases
Telomere
Mendelian Randomization Analysis
2016
2 Citations

Affective disorders, psychosis and dementia in a community sample of older men with and without Parkinson's disease

Almeida, O. P., McCaul, K., Hankey, G. J., Yeap, B. B., Golledge, J. & Flicker, L., 30 Sep 2016, In : PLoS One. 11, 9, p. 1-13 e0163781

Research output: Contribution to journalArticle

Open Access
Psychotic Affective Disorders
dementia
Parkinson disease
Mood Disorders
Parkinson Disease
9 Citations

Associations of demographic and behavioural factors with glycaemic control in young adults with type 1 diabetes mellitus

Osan, J. K., Punch, J. D., Watson, M. A., Chan, Y. X., Barrie, P., Fegan, P. G. & Yeap, B. B., 2016, In : Internal Medicine Journal. 46, 3, p. 332-338 7 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Young Adult
Demography
Risk-Taking
Western Australia
8 Citations
Open Access
File
Men's Health
Cohort Studies
Depression
Electronic Health Records
Dementia
2 Citations

Development of Land Use Regression models for particulate matter and associated components in a low air pollutant concentration airshed

Dirgawati, M., Heyworth, J. S., Wheeler, A. J., McCaul, K. A., Blake, D., Boeyen, J., Cope, M., Yeap, B. B., Nieuwenhuijsen, M., Brunekreef, B. & Hinwood, A., 1 Nov 2016, In : Atmospheric Environment. 144, p. 69-78 10 p.

Research output: Contribution to journalArticle

particulate matter
land use
air pollutant
pollutant concentration
absorbance
13 Citations

Duration of diabetes and its association with depression in later life: The Health in Men Study (HIMS)

Almeida, O., Mccaul, K., Hankey, G., Yeap, B., Golledge, J., Norman, P. & Flicker, L., Apr 2016, In : Maturitas. 86, p. 3-9 7 p.

Research output: Contribution to journalArticle

Open Access
Men's Health
Medical problems
Health
Depression
Odds Ratio
24 Citations

Endocrine Society of Australia position statement on male hypogonadism (part 1): assessment and indications for testosterone therapy

Yeap, B. B., Grossmann, M., McLachlan, R. I., Handelsman, D. J., Wittert, G. A., Conway, A. J., Stuckey, B. G. A., Lording, D. W., Allan, C. A., Zajac, J. D. & Burger, H. G., 15 Aug 2016, In : The Medical journal of Australia. 205, 4, p. 173-178 6 p.

Research output: Contribution to journalArticle

Eunuchism
Testosterone
Hypogonadism
Follicle Stimulating Hormone
Luteinizing Hormone
7 Citations

Endocrine Society of Australia position statement on male hypogonadism (Part 2): Treatment and therapeutic considerations

Yeap, B., Grossmann, M., Mclachlan, R. I., Handelsman, D. J., Wittert, G. A., Conway, A. J., Stuckey, B., Lording, D. W., Allan, C. A., Zajac, J. D. & Burger, H. G., 2016, In : Medical Journal of Australia. 205, 5, p. 228-231

Research output: Contribution to journalArticle

Eunuchism
Testosterone
Therapeutics
Hypogonadism
Androgens
14 Citations

Epidemiological and mendelian randomization studies of dihydrotestosterone and estradiol and leukocyte telomere length in men

Yeap, B., Knuiman, M., Divitini, M., Hui, J., Arscott, G. M., Handelsman, D. J., Mclennan, S. V., Twigg, S. M., McQuillan, B., Hung, J. & Beilby, J., 1 Mar 2016, In : Journal of Clinical Endocrinology and Metabolism. 101, 4, p. 1299-1306 8 p.

Research output: Contribution to journalArticle

Open Access
File
Dihydrotestosterone
Telomerase
Telomere
Random Allocation
Polymorphism
5 Citations
Open Access
File
Dihydrotestosterone
Testosterone
Estradiol
Cardiovascular Diseases
Mortality
2 Citations

Plasma ferritin concentrations are not associated with abdominal aortic aneurysm diagnosis, size or growth

Moxon, J. V., Jones, R. E., Norman, P. E., Clancy, P., Flicker, L., Almeida, O. P., Hankey, G. J., Yeap, B. B. & Golledge, J., Aug 2016, In : Atherosclerosis. 251, p. 19-24

Research output: Contribution to journalArticle

Abdominal Aortic Aneurysm
Ferritins
Iron Overload
Growth
Odds Ratio
6 Citations

Prevalence and prognosis of a low serum testosterone in men with type 2 diabetes: the Fremantle Diabetes Study Phase II

Hamilton, E. J., Davis, W. A., Makepeace, A., Lim, E. M., Yeap, B. B., Peters, K. E. & Davis, T. M. E., Sep 2016, In : Clinical Endocrinology. 85, 3, p. 444-452

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Testosterone
Serum
Independent Living
Reproductive Health
13 Citations

Prospective longitudinal study of testosterone and incident depression in older men: The health in men study

Ford, A., Yeap, B., Flicker, L., Hankey, G., Chubb, P., Handelsman, D. J., Golledge, J. & Almeida, O., 1 Feb 2016, In : Psychoneuroendocrinology. 64, p. 57-65 9 p.

Research output: Contribution to journalArticle

Open Access
File
Men's Health
Longitudinal Studies
Testosterone
Prospective Studies
Depression