Brendan O'Leary


  • The University of Western Australia (M310), 35 Stirling Highway,

    6009 Perth


  • Source: Scopus
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Personal profile


-BSc (Honours) Biochemistry, Queen's University, Kingston Canada, 2006
-PhD Biology Queen's University, Kingston, Canada, 2011
-Post-doctoral researcher, Dept of Plant Sciences, University of Oxford, 2011-2014
-Joined the ARC Centre of Excellence in Plant Energy Biology in 2015 as a DECRA Post-doctoral Fellow

Funding overview

Discovery Early Career Research Award 2015


There is a long standing interest in manipulating metabolism in plants to improve the production and quality of food, medicine and other consumable products. However, metabolic engineering in plants is notoriously unpredictable – really a hit or miss affair. With a focus on plant primary metabolism, I study the post-translation mechanisms that control and balance fluxes through metabolic pathways with the aim of improving our ability to accurately manipulate these important pathways.
My experimental approach combines metabolomics with enzymology. In particular enzymes are purified and studied from their native tissues to understand the post-translational modifications that control enzyme activity in vivo.

Research expertise keywords

  • Plant metabolism
  • Plant respiration
  • Metabolic regulation
  • Post-translational modifications of enzymes
  • Metabolomics
  • Phosphoenolpyruvate carboxylase


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