Personal profile
Biography
Dr Ben Zwick is a Research Fellow in the School of Engineering at The University of Western Australia (UWA). His mission is to apply computational science, biophysics and biomedical engineering to understand, prevent, and treat human diseases, including epilepsy, brain cancer and depression.
Ben was born in Zürich, Switzerland, and educated in Perth, Western Australia, where he earned a Bachelor's degree with honours in Mechanical Engineering and a PhD in computational biomechanics from UWA. His academic research is guided by his industry experience in engineering and design, providing a unique perspective on the practical challenges of turning ideas into reality.
Ben is dedicated to making state-of-the-art medical treatments accessible to all by democratizing healthcare through open science, open data, and open-source software and hardware for medical devices. Towards this goal, he collaborates with multidisciplinary research teams to tackle scientifically significant and challenging problems in biomedical science and engineering, where his technical expertise can make a meaningful impact, ultimately improving the health outcomes and lives of others.
Research interests
- Computational science and biophysics for medicine
- Image-guided surgical planning and navigation
- Epilepsy
- Brain cancer
- Transcranial magnetic stimulation (TMS)
- Cardiovascular disease
- Computational solid and fluid mechanics
- Computational electromagnetics
- Computational biomechanics
- Biomedical engineering
- Computer and robot-aided surgery
- Mathematical modelling
- Numerical methods (especially finite element, meshless and meshfree methods)
- Artificial intelligence (AI), machine learning and artificial neural networks (ANNs)
- Medical image analysis and image processing
- High-performance computing
Current projects
Research projects
- Physics-informed neural networks (PINNs) for estimation of brain shift during neurosurgery
- Biomechanics-based neuroimage registration for tumour resection and epilepsy surgery planning
- Brain electrical activity modelling for epilepsy surgery planning
- Biomechanics of the brain-skull interface
- Simulation of needle insertion into soft tissues
Software projects
- SlicerCBM: https://github.com/SlicerCBM
- MVox: https://github.com/benzwick/mvox
- SofTiSim: https://gitlab.com/benzwick/SofTiSim
- ExplicitSim: https://bitbucket.org/explicitsim/explicitsim
Additional software can be found in the following repositories:
Teaching overview
Ben has served as a lecturer, unit coordinator and tutor for the following units of the Bachelor of Engineering (BEng) and Master of Professional Engineering (MPE) programmes at The University of Western Australia:
- 2024: Numerical Methods and Modelling (guest lecturer for numerical integration, roots of nonlinear equations, optimisation methods and introduction to neural networks)
- 2023 – 2024: Biomechanics (unit coordinator, lecturer and tutor)
- 2022: Cardiovascular Biomechanics (unit coordinator, lecturer and tutor)
- 2021: Mechanisms and Machines (tutor)
- 2016 – 2018: Numerical Methods and Modelling (tutor)
- 2014 – 2016: Finite Element Methods (tutor)
Industry keywords
- Bioengineering
- Bioinformatics
- Biotechnology
- Digital Health
- Health
- Medical Devices
- Not for Profit
Research expertise keywords
- Computational Science
- Computational Biophysics
- Computational Fluid Dynamics (CFD)
- Computational Electromagnetics
- Computational Solid Mechanics
- Numerical Methods
- Machine Learning
- Biomedical Engineering
- Mathematical Modelling
- Medical Image Analysis
- Finite Element Method
- High Performance Computing
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Fingerprint
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Collaborations and top research areas from the last five years
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Patient-specific solution of the electrocorticography forward problem in deforming brain
Zwick, B. F., Bourantas, G. C., Safdar, S., Joldes, G. R., Hyde, D. E., Warfield, S. K., Wittek, A. & Miller, K., Nov 2022, In: NeuroImage. 263, 119649.Research output: Contribution to journal › Article › peer-review
Open Access5 Link opens in a new tab Citations (Scopus) -
SlicerCBM: automatic framework for biomechanical analysis of the brain
Safdar, S., Zwick, B. F., Yu, Y., Bourantas, G. C., Joldes, G. R., Warfield, S. K., Hyde, D. E., Frisken, S., Kapur, T., Kikinis, R., Golby, A., Nabavi, A., Wittek, A. & Miller, K., Oct 2023, In: International Journal of Computer Assisted Radiology and Surgery. 18, 10, p. 1925-1940 16 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Link opens in a new tab Citations (Scopus) -
Image data and computational grids for computing brain shift and solving the electrocorticography forward problem
Zwick, B. F., Safdar, S., Bourantas, G. C., Joldes, G. R., Hyde, D. E., Warfield, S. K., Wittek, A. & Miller, K., Jun 2023, In: Data in Brief. 48, 109122.Research output: Contribution to journal › Data article › peer-review
Open Access -
Hexahedral mesh of anatomical atlas for construction of computational human brain models: Applications to modeling biomechanics and bioelectric field propagation
Huynh, A., Zwick, B., Jamshidian, M., Halle, M., Wittek, A. & Miller, K., 2 Oct 2024, USA: arXiv.Research output: Working paper › Preprint
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Deep Biomechanically-Guided Interpolation for Keypoint-Based Brain Shift Registration
Assis, T., Machado, I. P., Zwick, B., Garcia, N. C. & Dorent, R., 2026, Collaborative Intelligence and Autonomy in Image-Guided Surgery - 1st International Workshop, COLAS 2025, Held in Conjunction with MICCAI 2025, Proceedings. Dou, Q., Ban, Y., Jin, Y., Bano, S. & Unberath, M. (eds.). Singapore: Springer Science + Business Media, p. 105-115 11 p. (Lecture Notes in Computer Science; vol. 16298 LNCS).Research output: Chapter in Book/Conference paper › Conference paper › peer-review
Datasets
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NeuriPhy - Neuroimaging Dataset for Physics-Informed Learning
Assis, T. (Creator), Dorent, R. (Creator), Zwick, B. F. (Creator), Garcia, N. C. (Creator) & Machado, I. P. (Creator), Zenodo, 12 May 2025
Dataset
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Data for patient-specific solution of the electrocorticography forward problem in deforming brain
Zwick, B. F. (Contributor), Safdar, S. (Contributor), Bourantas, G. C. (Contributor), Joldes, G. R. (Contributor), Hyde, D. E. (Contributor), Warfield, S. K. (Contributor), Wittek, A. (Contributor) & Miller, K. (Contributor), Zenodo, 10 Nov 2022
Dataset
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Data for patient-specific solution of the electrocorticography forward problem in deforming brain
Zwick, B. F. (Creator), Safdar, S. (Creator), Bourantas, G. (Creator), Joldes, G. (Creator), Hyde, D. E. (Creator), Warfield, S. K. (Creator), Wittek, A. (Creator) & Miller, K. (Creator), Zenodo, 2022
DOI: 10.5281/zenodo.7309089, https://zenodo.org/record/7309089
Dataset
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Data for patient-specific solution of the electrocorticography forward problem in deforming brain
Zwick, B. F. (Creator), Safdar, S. (Creator), Bourantas, G. C. (Creator), Joldes, G. (Creator), Hyde, D. E. (Creator), Warfield, S. K. (Creator), Wittek, A. (Creator) & Miller, K. (Creator), Zenodo, 2022
DOI: 10.5281/zenodo.7687631, https://zenodo.org/record/7687631
Dataset
Projects
- 4 Finished
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WA Near-miss Awards: Ideas Grants 2024-25 - Computational biophysics to improve epilepsy presurgical planning: source localisation in a deforming brain
Zwick, B. (Investigator 01)
Department of Health (Western Australia)
6/05/25 → 7/05/26
Project: Research
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Real-Time Brain Shift Correction in Neurosurgery Using Physics-Informed Neural Networks
Jamshidian, M. (Chief Investigator), Fichtinger, G. (CoPI), Kikinis, R. (CoPI), Miller, K. (CoPI), Wittek, A. (CoPI) & Zwick, B. (CoPI)
The University of Western Australia
1/01/25 → 31/12/25
Project: Research
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WA Near-miss Awards: Ideas Grants 2023-24 - Can physics-informed neural networks improve registration accuracy for image-guided neurosurgery?
Zwick, B. (Investigator 01)
Department of Health (Western Australia)
7/06/24 → 7/05/25
Project: Research
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Computational Biophysics for Medicine in 3D Slicer
Zwick, B. (Chief Investigator), Fichtinger, G. (Investigator), Kikinis, R. (Investigator), Kikinis, R. (Investigator), Miller, K. (Investigator), Wittek, A. (Investigator), Fichtinger, G. (CoPI), Kikinis, R. (CoPI), Miller, K. (CoPI) & Wittek, A. (CoPI)
The University of Western Australia
1/01/23 → 31/12/23
Project: Research
Press/Media
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MFEM workshop showcases application variety and broad impact
16/11/22
1 item of Media coverage
Press/Media: Press / Media