• The University of Western Australia (M504), 35 Stirling Highway,

    6009 Perth

    Australia

  • 414 Citations
  • 8 h-Index
20122021
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Research Output 2012 2019

  • 414 Citations
  • 8 h-Index
  • 13 Article
  • 1 Abstract/Meeting Abstract
  • 1 Letter
Filter
Article
2019
Fibrosis
Blood Platelets
Bone Marrow
Neoplasms
Megakaryocytes

Systematic bias assessment in solid tissue 10x scRNA-seq workflows

Denisenko, E., Guo, B., Jones, M., Hou, R., De Kock, L., Lassmann, T., Poppe, D., Clement, O., Simmons, R. K., Lister, R. & Forrest, A., 6 Nov 2019, (Submitted) In : bioRxiv. p. 1-47 47 p., 832444.

Research output: Contribution to journalArticle

Small Cytoplasmic RNA
Workflow
RNA Sequence Analysis
Chromium
Genomics
2018
1 Citation (Scopus)
Plasma Cells
Reference Values
Bone Marrow
Lymphocytes
Biopsy
2017
2 Citations (Scopus)

Megakaryocytes in myeloproliferative neoplasms have unique somatic mutations

Guo, B. B., Allcock, R. J., Mirzai, B., Malherbe, J. A., Choudry, F. A., Frontini, M., Chuah, H., Liang, J., Kavanagh, S. E., Howman, R., Ouwehand, W. H., Fuller, K. A. & Erber, W., Jul 2017, In : The American Journal of Pathology. 187, 7, p. 1512–1522

Research output: Contribution to journalArticle

Megakaryocytes
Mutation
Primary Myelofibrosis
Bone Marrow
Neoplasms
2016
4 Citations (Scopus)

Dysregulation of the intrinsic apoptotic pathway mediates megakaryocytic hyperplasia in myeloproliferative neoplasms

Malherbe, J., Fuller, K., Mirzai, B., Kavanagh, S., So, C. C., Ip, H. W., Guo, B., Forsyth, C., Howman, R. & Erber, W., 2016, In : Journal of Clinical Pathology. 69, 11, p. 1017-1024

Research output: Contribution to journalArticle

Open Access
Megakaryocytes
Hyperplasia
Caspase 9
Primary Myelofibrosis
Neoplasms
9 Citations (Scopus)

Megakaryocytic hyperplasia in myeloproliferative neoplasms is driven by disordered proliferative, apoptotic and epigenetic mechanisms

Malherbe, J., Fuller, K., Arshad, A., Nangalia, J., Romeo, G., Hall, S., Meehan, K., Guo, B., Howman, R. & Erber, W., 2016, In : Journal of Clinical Pathology. 69, 2, p. 155-163

Research output: Contribution to journalArticle

Open Access
Megakaryocytes
Epigenomics
Hyperplasia
Neoplasms
Mutation
49 Citations (Scopus)

Stimulating the release of exosomes increases the intercellular transfer of prions

Guo, B., Bellingham, S. & Hill, A., 2016, In : Journal of Biological Chemistry. 291, 10, p. 5128-5137

Research output: Contribution to journalArticle

Exosomes
Prions
Monensin
Prion Diseases
PrPC Proteins
2015
81 Citations (Scopus)

The neutral sphingomyelinase pathway regulates packaging of the prion protein into exosomes

Guo, B., Bellingham, S. & Hill, A., 2015, In : Journal of Biological Chemistry. 290, 6, p. 3455-3467

Research output: Contribution to journalArticle

Exosomes
Sphingomyelin Phosphodiesterase
Prions
Product Packaging
Packaging
19 Citations (Scopus)

The secret life of extracellular vesicles in metal homeostasis and neurodegeneration

Bellingham, S., Guo, B. & Hill, A., 2015, In : Biology of the Cell. 107, 11, p. 389–418

Research output: Contribution to journalArticle

Homeostasis
Metals
Prion Diseases
Alzheimer Disease
Exosomes
2014
14 Citations (Scopus)

Pathogenic mutations within the hydrophobic domain of the prion protein lead to the formation of protease-sensitive prion species with increased lethality

Coleman, B., Harrison, C., Guo, B., Masters, C., Barnham, K., Lawson, V. & Hill, A., 2014, In : Journal of Virology. 88, 5, p. 2690-2703

Research output: Contribution to journalArticle

Prions
prions
Peptide Hydrolases
proteinases
Prion Diseases
18 Citations (Scopus)

Prion infection impairs cholesterol metabolism in neuronal cells

Cui, H., Guo, B., Scicluna, B., Coleman, B., Lawson, V., Ellett, L., Meikle, P., Bukrinsky, M., Mukhamedova, N., Sviridov, D. & Hill, A., 2014, In : Journal of Biological Chemistry. 289, 2, p. 789-802

Research output: Contribution to journalArticle

Prions
Metabolism
Cholesterol
Infection
ATP-Binding Cassette Transporters
2012
206 Citations (Scopus)

Exosomes: vehicles for the transfer of toxic proteins associated with neurodegenerative diseases?

Bellingham, S. A., Guo, B., Coleman, B. M. & Hill, A. F., 2012, In : Frontiers in Physiology. 3, Article 124, p. 1-12

Research output: Contribution to journalArticle

Open Access
11 Citations (Scopus)

The C-terminal domain of Escherichia coli dihydrodipicolinate synthase (DHDPS) is essential for maintenance of quaternary structure and efficient catalysis

Guo, B., Devenish, S. R. A., Dobson, R. C. J., Muscroft-Taylor, A. C. & Gerrard, J. A., 2012, In : Biochemical and Biophysical Research Communications. 380, p. 802-806

Research output: Contribution to journalArticle