Projects per year
Personal profile
Biography
I completed my PhD degree at the University of Melbourne in 2014, where I investigated the role of exosomes (small membrane-bound vesicles released by cells) in prion disease. I used a range of molecular and cell biology techniques to examine how different cellular pathways regulate exosome formation, packaging of the prion protein, release from cells and subsequent intercellular transmission of prion infectivity.
I worked as a Research Assistant at the Bio21 Institute, University of Melbourne, where I undertook my PhD studies. I assisted with several projects, including continuations of my PhD project. In addition, I received training for and worked on next-generation sequencing (NGS) projects using the Ion Torrent Personal Genome Machine (PGM) platform.
I joined the Translational Cancer Pathology Laboratory in 2014, where I will apply my molecular and NGS skills to cancer research, with a focus on molecular genomic studies of melanoma, glioma and haematological malignancies.
Previous positions
Research
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Projects 2015 2020
Tumour-educated platelets as a predictive biomarker in melanoma
Guo, B., Gray, E. & Khattak, A.
1/01/19 → 30/06/20
Project: Research
A Novel Blood-Based Approach to Predict Fibrotic Progression in Myeloproliferative Neoplasms
Guo, B., Allcock, R., Linden, M., Fuller, K. & Hoffman, W.
1/08/18 → 31/07/19
Project: Research
Ultra-Sensitive Minimally-Invasive Molecular Disease Monitoring of Acute Myeloid Leukaemia
Allcock, R., Guo, B., Hoffman, W., Chuah, H. & Leahy, M.
1/01/18 → 30/06/19
Project: Research
Evaluation of animal models of fibrotic progression in Myeloproliferative Neoplasms
Allcock, R., Guo, B., Linden, M. & Crispino, J.
University of Western Australia
1/01/18 → 31/12/18
Project: Research
Research Output 2012 2018
Automated enumeration of lymphoid and plasma cells in bone marrow to establish normal reference ranges
Liang, J., Malherbe, J. A. J., Fuller, K. A., Mirzai, B., George, C., Carter, T. L., Cole, C. H., Guo, B. B., Meehan, K. & Erber, W. N., 1 Oct 2018, In : Journal of Clinical Pathology. 71, 10, p. 916-925 10 p.Research output: Contribution to journal › Article
A mutation in PTPN11 may drive leukemic transformation in a case of essential thrombocythemia
Guo, B., Liang, J., Allcock, R., Mirzai, B., Augustson, B., Howman, R., Fuller, K. & Erber, W., 7 Jun 2017, In : LEUKEMIA & LYMPHOMA. 59, 1, p. 245-248Research output: Contribution to journal › Letter
Detection of therapeutic targets in carcinomas of unknown primary
Clynick, B., Dessauvagie, B., Strerrett, G., Harvey, N., Subramaniam, S., Herron, J., Allcock, R., Guo, B., Saunder, C., Erber, W. & Meehan, K., Sep 2017, In : Annals of Oncology. 28, 1 p.Research output: Contribution to journal › Abstract/Meeting Abstract
Megakaryocytes in myeloproliferative neoplasms have unique somatic mutations
Guo, B. B., Allcock, R. J., Mirzai, B., Malherbe, J. A., Choudry, F. A., Frontini, M., Chuah, H., Liang, J., Kavanagh, S. E., Howman, R., Ouwehand, W. H., Fuller, K. A. & Erber, W., Jul 2017, In : The American Journal of Pathology. 187, 7, p. 1512–1522Research output: Contribution to journal › Article
Dysregulation of the intrinsic apoptotic pathway mediates megakaryocytic hyperplasia in myeloproliferative neoplasms
Malherbe, J., Fuller, K., Mirzai, B., Kavanagh, S., So, C. C., Ip, H. W., Guo, B., Forsyth, C., Howman, R. & Erber, W., 2016, In : Journal of Clinical Pathology. 69, 11, p. 1017-1024Research output: Contribution to journal › Article