Personal profile
Biography
In the past few years Prof. Marshall’s laboratory has developed enhanced methods for non-invasive studies on the molecular epidemiology of H. pylori, notably rapid breath test methods and retrieval of the organism (and culture) from a swallowed string. The H. pylori laboratory has produced seven Microbiology Honors graduates and currently has one Honors and three PhD candidates enrolled. Prof. Marshall has also recently succeeded in drawing investor funding from international and national sources for the creation of Ondek; a small biotech company focused on developing new biologic delivery systems for vaccines and therapeutics, utilizing the unique characteristics of genetically modified Helicobacter pylori.
Roles and responsibilities
• Clinical Professor of Medicine and Microbiology, UWA
• Director of the Marshall Centre for Infectious Diseases Research & Training, UWA
• Consultant Gastroenterologist, Sir Charles Gairdner Hospital
• Founder and Director of ONDEK, a biotechnology company
• Founder and Director of TRI-MED, a diagnostics company
• Member, Western Australian Technology and Industry Advisory Council
• Honorary Patron of Scitech, the Ear Science Institute and Fremantle Hospital Medical Research Foundation
• Honorary Patron of Warren Jones Institute for Community Health and Medical Research at Fiona Stanley Hospital
Future research
• Genomics and the evolution of Helicobacter
• Expert Patient Treatment System (EPTS) software application
• Establishment of a Helicobacter culture collection with linked genome and clinical data (e-bio bank)
Research
Testing novel antibiotic compounds on H. pylori clinical isolates
Monitoring the cure rate of quadruple therapies against multi-drug resistant H. pylori strains
Genomic sequencing and analysis of bacterial genomes
The evolution of Helicobacter species
H. pylori toxin and regulatory genes
The effects of H. pylori on the immune system
Research expertise keywords
- Antibiotic resistance in helicobacter pylori
- Novel therapies to treat helicobacter pylori
- Development of a treatment software application
- Helicobacter genomics and evolution
- Helicobacter pylori toxin and regulatory genes
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Advances in Helicobacter pylori lipopolysaccharide structure and function
Tang, X., Tay, A., Benghezal, M., Marshall, B. J., Tang, H. & Li, H., 11 Aug 2025, (E-pub ahead of print) In: FEMS Microbiology Reviews. 49, 14 p., fuaf034.Research output: Contribution to journal › Review article › peer-review
Open Access4 Link opens in a new tab Citations (Scopus) -
Antimicrobial Resistance of Helicobacter pylori Among Chinese Yi Population
Zhang, J., Wang, Y., Chen, L., Zhang, Q., Song, X., Ma, F., Ma, S., Ma, Y., Shen, Y., Feng, P., Tay, A. C. Y., Marshall, B. J., Tang, H. & Li, H., 15 Nov 2025, In: Journal of Infectious Diseases. 232, Suppl 4, p. S359-S366 8 p.Research output: Contribution to journal › Article › peer-review
1 Link opens in a new tab Citation (Scopus) -
Antimicrobial Resistance Patterns of Clinical Helicobacter pylori Isolates From Gastric Cancer Patients
Zhang, Y., Liu, K., Song, X., Shen, Y., Tay, A., Marshall, B. J., Tang, H. & Li, H., 20 Nov 2025, In: Journal of Infectious Diseases. 232, p. S412-S417Research output: Contribution to journal › Article › peer-review
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Application of machine learning-assisted surface-enhanced Raman spectroscopy in medical laboratories: Principles, opportunities, and challenges
Tang, J. W., Yuan, Q., Zhang, L., Marshall, B. J., Yen Tay, A. C. & Wang, L., Mar 2025, In: TrAC - Trends in Analytical Chemistry. 184, 18 p., 118135.Research output: Contribution to journal › Review article › peer-review
43 Link opens in a new tab Citations (Scopus) -
Comparative Evaluation of Modified Agar Dilution and Standard Agar Dilution Methods for Antimicrobial Susceptibility Testing of Helicobacter pylori
Tang, X., Shen, Y., Song, X., He, B., You, S., Tay, A., Benghezal, M., Marshall, B. J., Tang, H. & Li, H., Nov 2025, In: Journal of Infectious Diseases. 232, p. S375-S383Research output: Contribution to journal › Article › peer-review
Datasets
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Additional file 1 of A re-testing range is recommended for 13C- and 14C-urea breath tests for Helicobacter pylori infection in China
Xiangyu, W. (Creator), Zhang, S. (Creator), Chua, E. (Creator), He, Y. (Creator), Li, X. (Creator), Liu, A. (Creator), Chen, H. (Creator), Wise, M. (Creator), Marshall, B. (Creator), Sun, D. (Creator), Li, X. (Creator) & Tay, C. Y. (Creator), Figshare, 13 Jun 2021
DOI: 10.6084/m9.figshare.14775610.v1, https://springernature.figshare.com/articles/dataset/Additional_file_1_of_A_re-testing_range_is_recommended_for_13C-_and_14C-urea_breath_tests_for_Helicobacter_pylori_infection_in_China/14775610/1
Dataset
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A re-testing range is recommended for 13C- and 14C-urea breath tests for Helicobacter pylori infection in China
Wang, X. (Creator), Zhang, S. (Creator), Chua, E. G. (Creator), He, Y. (Creator), Li, X. (Creator), Liu, A. (Creator), Chen, H. (Creator), Wise, M. J. (Creator), Marshall, B. J. (Creator), Sun, D. (Creator), Li, X. (Creator) & Tay, C. Y. (Creator), Figshare, 13 Jun 2021
DOI: 10.6084/m9.figshare.c.5465158
Dataset
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Antibiotic resistance patterns of Helicobacter pylori strains isolated from the Tibet Autonomous Region, China
Tang, X. (Creator), Wang, Z. (Creator), Shen, Y. (Creator), Song, X. (Creator), Benghezal, M. (Creator), Marshall, B. J. (Creator), Tang, H. (Creator) & Li, H. (Creator), Figshare, 15 Aug 2022
DOI: 10.6084/m9.figshare.c.6148152
Dataset
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Additional file 1 of A re-testing range is recommended for 13C- and 14C-urea breath tests for Helicobacter pylori infection in China
Xiangyu, W. (Creator), Zhang, S. (Creator), Chua, E. (Creator), He, Y. (Creator), Li, X. (Creator), Liu, A. (Creator), Chen, H. (Creator), Wise, M. (Creator), Marshall, B. (Creator), Sun, D. (Creator), Li, X. (Creator) & Tay, C. Y. (Creator), Figshare, 13 Jun 2021
DOI: 10.6084/m9.figshare.14775610, https://springernature.figshare.com/articles/dataset/Additional_file_1_of_A_re-testing_range_is_recommended_for_13C-_and_14C-urea_breath_tests_for_Helicobacter_pylori_infection_in_China/14775610
Dataset
Projects
- 44 Finished
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Precision-immunology assisted by on-chip machine learning to create a test for neutralizing antibodies to SARS-CoV-2
Imrie, A. (Investigator 01), Marshall, B. (Investigator 02), Lundin, S. (Investigator 03), Fulurija, A. (Investigator 04) & Hubble, L. (Investigator 05)
Department of Health (Western Australia)
14/06/21 → 13/06/22
Project: Research
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National Foundation for Australia-China Relations 2020-21 Competitive Grants Program
Marshall, B. (Investigator 01) & Tay, A. (Investigator 02)
Department of Foreign Affairs & Trade
1/01/21 → 31/08/22
Project: Research
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The Noisy Guts Project: the development of an acoustic belt that non-invasively diagnoses and monitors common gut disorders and diseases
Marshall, B. (Investigator 01)
NHMRC National Health and Medical Research Council
1/01/20 → 30/06/22
Project: Research
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The Noisy Guts Project
Marshall, B. (Investigator 01), Muir, J. (Investigator 02) & Webberley, M. (Investigator 03)
The University of Western Australia
1/01/19 → 31/12/19
Project: Research
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MHRIF Round 22 - Barry Marshall
Marshall, B. (Investigator 01)
Department of Health (Western Australia)
1/01/19 → 31/12/19
Project: Research
Prizes
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2025 VinUni Accelerating Research Excellence Program grant
Khun, P. A. (Recipient), Tay, A. (Recipient) & Marshall, B. (Recipient), Jan 2026
Prize
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2018 WA IOTY Emerging Innovation Category Winners
Muir, J. (Recipient), Marshall, B. (Recipient), Webberley, M. (Recipient) & Du, X. (Recipient), 7 Nov 2018
Prize
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The Nobel Prize in Physiology or Medicine 2005
Marshall, B. (Recipient) & Warren, R. (Recipient), 2005
Prize
Press/Media
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The Noisy Guts Project
Marshall, B. & Webberley, M.
14/12/18
1 item of Media coverage
Press/Media: Press / Media