Barry Marshall

Professor, MB BS W.Aust., FRACP, FRS, FAA

  • The University of Western Australia (M504), 35 Stirling Highway, Room 2.14, L Block, QEII Medical Centre, Nedlands

    6009 Perth


  • 1865 Citations
  • 23 h-Index
1988 …2020

Research output per year

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Personal profile


Prof. Barry Marshall has managed a Helicobacter pylori research group almost since his discovery of Helicobacter pylori with Robin Warren in 1982. Prof. Marshall has received many honors for his work on Helicobacter pylori, most notably they include, the Nobel Prize for Medicine or Physiology in 2005, The William Beaumont Prize in 2006 (American Gastroenterology Association), in 1995 the Albert Lasker Award (Albert & Mary Lasker Foundation), and in 1998 the Dr. A. H. Heineken Prize for Medicine (The Alfred Heineken Foundation, Amsterdam). In 2007 Prof. Marshall was awarded the honour of Western Australian of the year and The Companion in the General Division of the Order of Australia (AC). Prof. Marshall holds professional memberships with the Australian Academy of Science, the British Royal Society, the Institute of Medicine (USA), the American Gastroenterological Association, the Australian Gastroenterological Society and the Australian Medical Association to name a few.

In the past few years Prof. Marshall’s laboratory has developed enhanced methods for non-invasive studies on the molecular epidemiology of H. pylori, notably rapid breath test methods and retrieval of the organism (and culture) from a swallowed string. The H. pylori laboratory has produced seven Microbiology Honors graduates and currently has one Honors and three PhD candidates enrolled. Prof. Marshall has also recently succeeded in drawing investor funding from international and national sources for the creation of Ondek; a small biotech company focused on developing new biologic delivery systems for vaccines and therapeutics, utilizing the unique characteristics of genetically modified Helicobacter pylori.

Roles and responsibilities

• Ambassador for Life Sciences for Western Australia
• Clinical Professor of Medicine and Microbiology, UWA
• Director of the Marshall Centre for Infectious Diseases Research & Training, UWA
• Consultant Gastroenterologist, Sir Charles Gairdner Hospital
• Founder and Director of ONDEK, a biotechnology company
• Founder and Director of TRI-MED, a diagnostics company
• Member, Western Australian Technology and Industry Advisory Council
• Honorary Patron of Scitech, the Ear Science Institute and Fremantle Hospital Medical Research Foundation
• Honorary Patron of Warren Jones Institute for Community Health and Medical Research at Fiona Stanley Hospital

Future research

• Basic and applied medical research in Helicobacter
• Genomics and the evolution of Helicobacter
• Expert Patient Treatment System (EPTS) software application
• Establishment of a Helicobacter culture collection with linked genome and clinical data (e-bio bank)


Profiling antibiotic resistance in H. pylori
Testing novel antibiotic compounds on H. pylori clinical isolates
Monitoring the cure rate of quadruple therapies against multi-drug resistant H. pylori strains
Genomic sequencing and analysis of bacterial genomes
The evolution of Helicobacter species
H. pylori toxin and regulatory genes
The effects of H. pylori on the immune system

Research expertise keywords

  • Antibiotic resistance in helicobacter pylori
  • Novel therapies to treat helicobacter pylori
  • Development of a treatment software application
  • Helicobacter genomics and evolution
  • Helicobacter pylori toxin and regulatory genes

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Research Output

Actual and estimated adenoma detection rates: a 2‐year monocentric colonoscopic screening outcome in Shenzhen, China

Zeng, L., Chua, E. G., Xiong, Y., Ding, S., Ai, H., Hou, Z., Loke, M. F., Goh, K. L., Tay, C. Y., Marshall, B. J., Zhu, F. & Sun, D., 16 Mar 2020, In : JGH Open.

Research output: Contribution to journalArticle

Open Access
  • Prevalence and risk factors of Helicobacter pylori infection among children in Kuichong Subdistrict of Shenzhen City, China

    Hu, J., Wang, X., Chua, E. G., He, Y., Shu, Q., Zeng, L., Luo, S., Marshall, B. J., Liu, A. & Tay, C. Y., 2020, In : PEERJ. 8, e8878.

    Research output: Contribution to journalArticle

    Open Access
  • Open Access
  • 1 Citation (Scopus)

    East-Asian Helicobacter pylori strains synthesize heptan-deficient lipopolysaccharide

    Li, H., Marceau, M., Yang, T., Liao, T., Tang, X., Hu, R., Xie, Y., Tang, H., Tay, A., Shi, Y., Shen, Y., Yang, T., Pi, X., Lamichhane, B., Luo, Y., Debowski, A. W., Nilsson, H. O., Haslam, S. M., Mulloy, B., Dell, A. & 3 others, Stubbs, K. A., Marshall, B. J. & Benghezal, M., 1 Jan 2019, In : PLoS Genetics. 15, 11, e1008497.

    Research output: Contribution to journalArticle

    Open Access
  • 2 Citations (Scopus)



    2018 WA IOTY Emerging Innovation Category Winners

    Josephine Muir (Recipient), Barry Marshall (Recipient), Mary Webberley (Recipient) & Xuhao Du (Recipient), 7 Nov 2018


  • Press / Media

    The Noisy Guts Project

    Barry Marshall & Mary Webberley


    1 item of Media coverage

    Press/Media: Press / Media