• The University of Western Australia (M408), 35 Stirling Highway,

    6009 Perth

    Australia

  • 4723 Citations
  • 28 h-Index
19982020

Research output per year

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Personal profile

Biography

Dr. Archa Fox is a senior lecturer in the School of Human Sciences and the School of Molecular Sciences at the University of Western Australia, and an affiliate investigator with the Harry Perkins Institute of Medical Research. Archa studied at the University of NSW and University of Sydney and was awarded her PhD in the year 2000 on a project supervised by Professor Merlin Crossley. She then moved to Dundee, UK, supported by a Wellcome Trust Fellowship to work with world-renowned scientist Professor Angus Lamond. Here she discovered a novel structure within cells that she named “paraspeckles”. In 2006 she moved back to Australia to start her own research group at the Western Australian Institute for Medical Research, now known as the Harry Perkins Institute of Medical Research. In 2015 she took up an academic position at the University of WA. Archa has an international reputation as a pioneer in the field of paraspeckle research and long noncoding RNA biology, leading to invitations to write seminal reviews and organise key symposia. She has been the recipient of the Marshall Medal of the Harry Perkins Institute in 2012, and the emerging leader award of the Australian/NZ Society of Cell and Developmental Biology in 2017.

Research expertise keywords

  • RNA biology
  • paraspeckles
  • long noncoding RNA
  • RNA-binding proteins
  • genome engineering
  • liquid phase separation
  • membraneless organelles
  • nuclear architecture

Industry keywords

  • Biotechnology
  • Medicine and Pharma
  • Health

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Research Output

Evidence of diverse movement strategies and habitat use by white sharks, Carcharodon carcharias, off southern Australia

Bradford, R., Patterson, T. A., Rogers, P. J., McAuley, R., Mountford, S., Huveneers, C., Robbins, R., Fox, A. & Bruce, B. D., 1 Jul 2020, In : Marine Biology. 167, 7, 96.

Research output: Contribution to journalArticle

Open Access
  • Matrix stiffness-sensitive long-non coding RNA NEAT1 seeded paraspeckles in cancer cells

    Todorovski, V., Fox, A. H. & Choi, Y. S., 15 Apr 2020, In : Molecular Biology of the Cell. 28 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • ALS-linked FUS mutations confer loss and gain of function in the nucleus by promoting excessive formation of dysfunctional paraspeckles

    An, H., Skelt, L., Notaro, A., Highley, J. R., Fox, A. H., La Bella, V., Buchman, V. L. & Shelkovnikova, T. A., 14 Jan 2019, In : Acta Neuropathologica Communications. 7, 14 p., 7.

    Research output: Contribution to journalArticle

    Open Access

    The emerging roles of hnRNPK

    Wang, Z., Qiu, H., He, J., Liu, L., Xue, W., Fox, A., Tickner, J. & Xu, J., 19 Sep 2019, In : Journal of Cellular Physiology.

    Research output: Contribution to journalReview article

  • 5 Citations (Scopus)

    A mitochondria–paraspeckle crosstalk

    Fox, A. H., 1 Oct 2018, In : Nature Cell Biology. 20, 10, p. 1108-1109 2 p.

    Research output: Contribution to journalEditorial

  • Datasets

    NONO PARCLIP U2OS data from: Functional Domains of NEAT1 Architectural lncRNA Induce Paraspeckle Assembly through Phase Separation

    Yamazaki, T. (Creator), Souquere, S. (Creator), Chujo, T. (Creator), Kobelke, S. (Creator), Chong, Y. S. (Creator), Fox, A. (Creator), Bond, C. (Creator), Nakagawa, S. (Creator), Pierron, G. (Creator), Hirose, T. (Creator), Gene Expression Omnibus (NCBI), 27 Jun 2018

    Dataset

    SFPQ PARCLIP U2OS data from: Functional Domains of NEAT1 Architectural lncRNA Induce Paraspeckle Assembly through Phase Separation

    Yamazaki, T. (Creator), Souquere, S. (Creator), Chujo, T. (Creator), Kobelke, S. (Creator), Chong, Y. S. (Creator), Fox, A. (Creator), Bond, C. (Creator), Nakagawa, S. (Creator), Pierron, G. (Creator), Hirose, T. (Creator), Gene Expression Omnibus (NCBI), 27 Jun 2018

    Dataset

    Functional domains of NEAT1 architectural lncRNA induce paraspeckle assembly through phase separation (Yamazaki et al.)

    Yamazaki, T. (Creator), Souquere, S. (Creator), Chujo, T. (Creator), Kobelke, S. (Creator), Chong, Y. S. (Creator), Fox, A. (Creator), Bond, C. (Creator), Nakagawa, S. (Creator), Pierron, G. (Creator), Hirose, T. (Creator), Mendeley Data, 28 Jun 2018

    Dataset

    NONO PARCLIP HeLa data from: Functional Domains of NEAT1 Architectural lncRNA Induce Paraspeckle Assembly through Phase Separation

    Yamazaki, T. (Creator), Souquere, S. (Creator), Chujo, T. (Creator), Kobelke, S. (Creator), Chong, Y. S. (Creator), Fox, A. (Creator), Bond, C. (Creator), Nakagawa, S. (Creator), Pierron, G. (Creator), Hirose, T. (Creator), Gene Expression Omnibus (NCBI), 27 Jun 2018

    Dataset

    SFPQ PARCLIP HeLa data from: Functional Domains of NEAT1 Architectural lncRNA Induce Paraspeckle Assembly through Phase Separation

    Yamazaki, T. (Creator), Souquere, S. (Creator), Chujo, T. (Creator), Kobelke, S. (Creator), Chong, Y. S. (Creator), Fox, A. (Creator), Bond, C. (Creator), Nakagawa, S. (Creator), Pierron, G. (Creator), Hirose, T. (Creator), Gene Expression Omnibus (NCBI), 27 Jun 2018

    Dataset

    Projects