Research output per year
Research output per year
Professor, MB BS W.Aust., MLdship Deakin., PhD W.Aust., FRACP., GAICD
The University of Western Australia (M460), 35 Stirling Highway,
6009 Perth
Australia
Prof Anna Nowak is Deputy Vice Chancellor (Research) at UWA, working with the UWA Executive to deliver research strategy and outcomes across the University. Previous roles include Pro Vice Chancellor (Health and Medical Research), Deputy Executive Dean (Faculty of Health and Medical Sciences) and Associate Dean (Research).
She is a graduate of the Australian Institute of Company Directors, the Oxford Women's Leadership Development Program (Oxford Said Business School), and the Australian Institute of Management Consultant Development Program. In 2022 she completed a Master of Leadership from Deakin University.
She spent 17 years as a Clinical Academic in the UWA Medical School and was also Director of the National Research Centre for Asbestos Related Diseases (NCARD) from 2017-2022. Her medical speciality is Medical Oncology, and she was a practicing medical oncologist at Sir Charles Gairdner Hospital from 2005 to 2021. She is a member of the Board of Directors, Cancer Council WA.
Prof Nowak has participated actively in mesothelioma research over the past 20 years, and has received international recognition in this area, including the 2020 Wagner Medal from the International Mesothelioma Interest Group. She is a member of the Board of the International Mesothelioma Interest Group and is currently President-Elect. She continues to complete work with other researchers in this field at Sir Charles Gairdner Hospital, UWA and internationally, although she relinquished clinical practice in mesothelioma at the end of 2021.
Her pre-clinical laboratory work in mesothelioma includes a PhD thesis on combination chemo-immunotherapy in a murine model; this work was awarded at local, national, and international level, winning the International Mesothelioma Interest Group New Investigator Award in 2002. She returned to UWA in 2005 to pursue laboratory work and clinical translational work in mesothelioma after a postdoctoral fellowship working in clinical trials research. She has given numerous oral presentations and published abstracts of her work at national and international meetings.
Her clinical research on unidimensional measurement of response in mesothelioma culminated in the development of the Modified RECIST Criteria for tumour response which have been widely accepted for use in clinical trials in this disease and updated in 2018. She is a regular invited speaker internationally on tumour measurement and clinical trials in mesothelioma. She also performed the first published validation of the use of a quality of life tool in clinical trials in mesothelioma. More recently, she has continued to investigate the role of PET scanning in prognostication and monitoring of treatment response in mesothelioma, and has been principal investigator of a number of local and national clinical trials in mesothelioma, particularly chemo-immunotherapy. She remains the principal investigator of the international DREAM3R clinical trial of chemo-immunotherapy vs. chemotherapy in mesothelioma.
Her other research and clinical focus was neuro-oncology. She had a longstanding research interest in brain tumour psycho-oncology and clinical trials and continues to complete existing collaborative work. She was a member of the COGNO scientific advisory committee since the inception of this co-operative clinical trials group, and was Chair of COGNO betwen 2017 and 2020. She was also active in brain tumour biobanking and collaborated with translational scientists in this field. She ceased practicing clinically in neuro-oncology in 2020.
Deputy Vice Chancellor (Research) 2022 -
• 2013
1. Morton R, King M, Fogarty G, Nowak AK. The cost-effectiveness of adjuvant whole brain radiotherapy for melanoma brain metastases: a trial-based and modelled economic evaluation. $184,475 2013-15. Cancer Australia
2. Halkett G, Nowak AK, Lobb E, Agar M, Miller L, Moorin R, Shaw T. Confidence to Care: A structured home-based support and education program for carers of people with high grade glioma. $99,315 2013. Cancer Council Western Australia.
3. Platell C, McCoy M, Zeps N, Nowak AK, Hemming C, Bulsara M. Predicting response to neo-adjuvant chemo-radiotherapy in patients with resectable rectal cancer. $196,824 2013-14. Cancer Council Western Australia.
4. Nowak AK. Analysis of regulatory T cell function in advanced cancer patients following a combination therapy of low-dose cyclophosphamide and standard care chemotherapy. $49309.60 2013-14. SCGH Research Advisory Committee Grant.
5. Francis R, Nowak AK. Imaging and modulating hypoxia in a murine model of malignant mesothelioma. $49,630.00 2013-14. SCGH Research Advisory Committee Grant.
• 2012
1. Miller L, Nowak AK. Confidence to Care: Development and piloting of a structured home-based support and education program for carers of people with high grade glioma. SCGH Research Fund. 2012/13 $45,299.60
2. Corica T, Nowak AK, Joseph DJ, Saunders C, Bulsara M. Patient preferences for adjuvant radiotherapy in early breast cancer Cancer and Palliative Care Research Unit Small Grants Scheme. 2012 $19,396.50
3. King A, Nowak AK, Halkett GB, Miller L. Confidence to Care: Development and piloting of a structured home-based support and education program for carers of people with high grade glioma. Cancer and Palliative Care Research Unit Small Grants Scheme. 2012 $25,000
4. Nowak AK, Rosenthal M, Simes J, Ryan G, Drummond K. Phase III trial of Concurrent and Adjuvant Temozolomide chemotherapy in non-1p/19q codeleted grade III astrocytoma. $396,175. Priority Driven Collaborative Cancer Research Scheme, Cancer Australia, 2012-14
5. Robinson C, Nowak AK, Lake RA. A High Fidelity Model of Malignant Mesothelioma. $? 2012/13 Cancer Council WA.
6. Severi G, McDonald K, Vajdic C, Nowak AK, Rosenthal M, Drummon K, Walker D, Jeffree R. Risk and Prognostic Factors for Glioma in Australia. $600,000 2012-14. Cancer Australia.
• 2011
1. Nelson D, Nowak AK, Alvarez J, Wikstrom M. Dendritic cells in malignant pleural mesothelioma. Slater and Gordon ad hoc Asbestos Research Fund. 2011. $5000
2. Robinson BWS, Lake RA, Nowak AK, Fisher S, Cleaver A. Cross Presentation and tumour immunology. NHMRC. 2012-2014
3. Nowak AK. Characterisation and predictive value of the human cellular response to chemoimmunotherapy with cisplatin, pemetrexed and CD40 activation. Cancer Council WA. 2012. $89,983.00
• 2010
1. Francis RJ, Nowak AK, McCarthy M, Loh N, Segard T, Bynevelt M, Morandeau L. C-11 methionine and F-18 Fluorothymidine PET imaging in suspected residual or recurrent glioma. ANZSNM Research Grant 2010 $18,600 (Francis and Nowak co-principal investigators).
2. Robinson BWS, Creaney J, Nowak AK, Lake R, Musk AW, Fazekas de St Groth B, Palmer L, Simpson R, Skates S, Watkins D. National Centre for Asbestos Related Diseases. NHMRC Centres for Research Excellence funding. 2010-2014. $4.5M.
• 2009
1. Creaney J, Segal A, Robinson BWS, Nowak AK. Is MUC1 a viable therapeutic target for patients with the asbestos-induced tumour malignant mesothelioma? NHMRC Project Grant 634377. 2010 $147700; 2011 $147700; 2012 $147700.
2. Holman CDJ, Emory J, Saunders CM, Walter FM, Moorin RE, Auret KA, Preen DB, Bulsara M. Nowak AK (AIB). NHMRC Partnership Project 572765. A Partnership Intervention Trial to Redress Treatment Delay and Improve Outcomes in Rural Cancer Patients. 2010-2014 $1 215 262 over 5 years.
• 2008
1. Nowak AK. New Independent Researcher Infrastructure Support Award. Department of Health, Western Australia. 2008 $10,000.
2. Fogarty G, Burmeister B, Drummond K, Nowak AK, Rezo A, Thompson J. Whole Brain Radiotherapy following local treatment of intracranial metastases of melanoma – a randomised phase III trial. Cancer Australia. 2009 $133,350; 2010 $150, 000
3. Nowak AK, Lake RA, Robinson BWS, Millward M, van der Most R. Optimising regulatory T cell depletion in combination with chemotherapy for enhanced anti-tumour immunity. NHMRC project grant. 2009 $154 000; 2010 $154 000; 2011 $154 000.
• 2007
1. Nowak AK. Communication Skills Training Grant. National Breast Cancer Centre. 2007. $3478.
2. Oldham L, Halkett G, Nowak AK. Determining and meeting the needs of Grade III-IV High Grade Glioma patients and their carers. 2008. HOTTAH grant. $24,971.72
3. Monterosso L, Aoun S, Joske D, Nowak A, Oliver D. Effect of a complementary therapy program on newly diagnosied patients with breast, brain and colorectal cancer: A randomized, controlled, crossover trial. Edith Cowan University Industry Collaboration Scheme. 2008/2009. $66,186.00
4. Lake RA, van der Most R, Nowak AK, Robinson BWS. NK cells as the missing link between anti-cancer chemotherapy and CD8 T cell responses. National Health and Medical Research Council.2008-10. $310,000.
5. Rosenthal M, Simes J, Hovey E, Drummond K, Nowak A, Walker D, Ryan G, Joseph D, Cher L, Price M, McDonald K. Co-operative Trials Group for Neuro-oncology (COGNO). Cancer Australia National Co-operative Clinical Trials Group funding. 2008. $198,000.
6. Palmer L, Nowak A, Teo C, McDonald K, Wheeler H, Joseph D, Robinson B. Australian Genomics and Clinical Outcomes of High Grade Glioma: AGOG. Cancer Council NSW Strategic Research Partnership (STREP) grant. 2008 $249 998; 2009 $247 029; 2010 $247 029; 2011 $247 029 2012 $247 029
• 2006
1. Nelson D, Nowak AK, Ganss R, Currie A. Australian Lung Foundation/Asbestos Research Group Award. Altering infiltrating immune cells and tumor-associated blood vessels in Malignant Mesothelioma using ‘Angio-immuno’ agents 2006: $160 000.
2. Byrne MJ, Van der Schaaf A, Francis R, Nowak A, Boucek J. Role of FLT PET in Malignant Pleural Mesothelioma – Prediction of Response to Chemotherapy. NHMRC Asbestos Research Program. 3%. 2007 $80 000; 2008 $80 000
3. Lake RA, Robinson C, Nowak AK. A National Resource for Mouse Models of Mesothelioma. NHMRC Asbestos Research Program. 3%. 2007 $200 000; 2008 $200 000
4. Robinson BWS, Reynolds P, Currie A, van der Most R, Lake RA, Nowak AK, Scott B. Integrating conventional mesothelioma therapies with immuno- and gener therapies. NHMRC Asbestos Research Program. 3%. 2007 $287 965; 2008 $284 425; 2009 $283 225
5. Nowak AK, Halkett G, Lobb E. Determining the needs of grade III-IV High Grade Glioma patients. Schering Plough Grant-in-aid. 2007 $15,303
6. Robinson BWS, Thompson PJ, Lake RA, Musk AW, Mutsaers S, Nowak AK. Centre of Research Excellence in Pulmonary and Environmental Medicine. NHMRC Centre of Research Excellence Grant. 2007-2011 $610 000 per annum
• 2005
1. Nowak AK, Taylor M, Joseph DJ, Knuckey N. Development of a multidisciplinary clinical database to evaluate treatment pathways and clinical outcomes in Brain Tumours at Sir Charles Gairdner Hospital. $36,159. Western Australian Clinical Oncology Group Clinical Service Co-ordination/Audit Grant 2005.
2. Nowak AK, Lake RA. Chemoimmunotherapy with cisplatin, pemetrexed and CD40 activation in a murine model of malignant mesothelioma. 2006:$29 946. UWA Research Grants Scheme.
3. Nowak AK, Lake RA, Robinson BWS. Chemoimmunotherapy – characterising and exploiting the immune response. Raine Priming Grant. 2006: $62,228.96; 2007: $71,374.54. Raine Medical Research Foundation.
4. Byrne MJ, van der Schaaf A, Nowak AK, Musk AW, Francis R, Robinson BWS, Segal A, Price R. Use of FDG PET in the assessment of tumour extent and response in Pleural Mesothelioma. Cancer Council WA. 2006: $59 000; 2007: $59 000.
5. Nowak AK, Lake RA. Developing a model of chemoimmunotherapy with cisplatin, pemetrexed and CD40 activation in a murine model of malignant mesothelioma. 2006: $9840. Sir Charles Gairdner Hospital Research Fund.
• 2004
1. Simes R, Hugh T, Gebski V, Riordan S, Fink M, Cebon J, Olnyk J, Crawford D, Price T, Zalcberg J, Nowak A. Adjuvant interferon and/or celecoxib for hepatoma. $42 000 (2004); $42 000 (2005). Cancer council of South Australia, Queensland Cancer Fund. Funds returned as study non-viable.
2. Stockler M, Wilcken N, Wyld D, Turner J, Byrne M, Nowak A, Koczwara B, Healey. The ZEST Trial a double-blind, placebo-controlled trial of Zoloft’s Effects on Symptoms and survival Time in Advanced Cancer. $89 825 (2004); $65 425 (2005). Cancer councils of SA, NSW.
• 2002
1. Lawson M, Nowak AK, Lake RA. Vaccination against mesothelioma using recombinant CMV expressing tumour antigens. $270,000 over 3 years. Granting body: Western Australian Institute of Medical Research.
Partnerships with the pharmaceutical industry for clinical trials in medical oncology, both investigator-initiated and pharma sponsored.
Chair, Evidence Based Medicine Working Party, Faculty of Medicine, Dentistry and Health Sciences.
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Leadership, MLdshp, Deakin University
Award Date: 1 Aug 2022
Medicine, PhD, Chemoimmunotherapy in a murine model of Mesothelioma, The University of Western Australia
Award Date: 30 Nov 2003
Medicine, MBBS, The University of Western Australia
Award Date: 1 Dec 1990
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Nowak, A. (Creator), Thoracic Oncology Group Australasia (TOGA), 2024
DOI: 10.58106/0ghq-8793, https://www.thoraciconcology.org.au/dream
Dataset
Lucas, M. (Investigator 01), Nowak, A. (Investigator 02) & Grover, P. (Investigator 03)
1/04/24 → 30/06/25
Project: Research
Hoang, T. (Investigator 01), Mohamed, S. (Investigator 02), Ioppolo, J. (Investigator 03), Espedal, H. (Investigator 04), Richardson, K. (Investigator 05), Cook, A. (Investigator 06), Morandeau, L. (Investigator 07), Chin, M. (Investigator 08), Francis, R. (Investigator 09), Nowak, A. (Investigator 10) & Ward, T. (Investigator 11)
8/01/24 → 8/07/26
Project: Research
Nowak, A. (Investigator 01)
NHMRC National Health and Medical Research Council
1/01/22 → 1/01/27
Project: Research
Nowak, A. (Investigator 01)
1/01/22 → 31/12/26
Project: Research
Nowak, A. (Recipient), 2018
Prize: Award
Nowak, A. (Member)
Activity: Memberships › Membership of council
Nowak, A. (Member)
Activity: Memberships › Membership of network
Nowak, A. (Member)
Activity: Memberships › Membership of council
Nowak, A. (Member)
Activity: Memberships › Membership of council
Nowak, A. (Member)
Activity: Memberships › Membership of committee
10/05/21
1 item of Media coverage
Press/Media: Press / Media
12/10/20
1 Media contribution
Press/Media: Press / Media
2/09/20
1 item of Media coverage
Press/Media: Press / Media
1/06/20
1 item of Media coverage
Press/Media: Press / Media