Photo of Andrew Woo
  • The University of Western Australia (M519), 35 Stirling Highway,

    6009 Perth

    Australia

  • 926 Citations
  • 11 h-Index
20022020

Research output per year

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Personal profile

Biography

Dr Andrew J. Woo completed his Bachelor of Science with Honours and a Doctor of Philosophy in Biochemistry at The University of Western Australia in 2004. He then began his postdoctoral training under Dr. Alan B. Cantor’s mentorship at Children’s Hospital Boston / Dana-Faber Cancer Institute at Harvard Medical School, Boston, USA. Transcriptional gene regulation is the focus of his research and his discoveries contributed to the study of blood disorders, cancer and stem cell biology. He has published in many prestigious journals including, Cell, Journal of Clinical Investigation, Molecular Cell, Genes and Development, Nature Communications, Blood and Molecular & Cellular Biology. He has returned to Perth in 2012 with a fellowship from Royal Perth Hospital Medical Research Foundation.

Roles and responsibilities

Research approaches include.
- Protein-Protein Interaction identification via proteomics
- Protein-DNA interaction mapping via next generation sequencing techniques
- Transcriptomics by next generation sequencing techniques
- Functional genomics
- Transgenic Mouse Models

Funding overview

2015 CIA, Cancer Council of Western Australia, Perth, Australia
2015 Sole CI, Medical Research Foundation WA, Perth, Australia
2014 Sole CI, Medical Research Foundation WA, Perth, Australia
2013 Sole CI, Medical Research Foundation WA, Perth, Australia
2012 Fellowship, Medical Research Foundation WA, Perth, Australia

Previous positions

Postdoctoral Research Fellow
Department of Hematology and Oncology
Boston Children's Hospital / Dana-Farber Cancer Institute,
Harvard Medical School,
Boston, MA, USA.

Research

Dr Andrew Woo’s research interests encompass understanding the transcriptional gene regulatory mechanisms in stem/progenitors cells of blood and epithelial cancer stem cells. With Dr. Peter Leedman at Harry Perkins Institute of Medical Research, he also investigates the role of small non-coding RNA processing complexes in epithelial cancer onset and metastasis.

Languages

English and Korean

External positions

Lecturer and Unit Coordinator, Edith Cowan University

1 Jul 20182 Feb 2021

Research expertise keywords

  • Transcriptional gene regulation
  • Stem cells and cancer
  • Haematopoiesis and blood disorders
  • Hormone-dependent cancers
  • Protein-protein interaction
  • Protein-DNA interaction
  • Mouse genetics
  • Bioinformatics

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Research Output

  • 926 Citations
  • 11 h-Index
  • 16 Article
  • 3 Abstract/Meeting Abstract
  • 1 Comment/debate
  • 1 Doctoral Thesis

Targeting RSPO3-LGR4 Signaling for Leukemia Stem Cell Eradication in Acute Myeloid Leukemia

Salik, B., Yi, H., Hassan, N., Santiappillai, N., Vick, B., Connerty, P., Duly, A., Trahair, T., Woo, A. J., Beck, D., Liu, T., Spiekermann, K., Jeremias, I., Wang, J., Kavallaris, M., Haber, M., Norris, M. D., Liebermann, D. A., D'Andrea, R. J., Murriel, C. & 1 others, Wang, J. Y., 1 Jun 2020, In : Cancer Cell.

Research output: Contribution to journalArticle

  • JMJD1C-mediated metabolic dysregulation contributes to HOXA9-dependent leukemogenesis

    Lynch, J. R., Salik, B., Connerty, P., Vick, B., Leung, H., Pijning, A., Jeremias, I., Spiekermann, K., Trahair, T., Liu, T., Haber, M., Norris, M. D., Woo, A. J., Hogg, P., Wang, J. & Wang, J. Y., 8 Jan 2019, In : Leukemia. 33, 6, p. 1400-1410 11 p.

    Research output: Contribution to journalArticle

  • 6 Citations (Scopus)

    MiR-101 suppresses the development of MLL-rearranged acute myeloid leukemia

    Gonzales-Aloy, E., Connerty, P., Salik, B., Liu, B., Woo, A. J., Haber, M., Norris, M. D., Wang, J. & Wang, J. Y., Jul 2019, In : Haematologica. 104, 7, p. e296-e299 4 p.

    Research output: Contribution to journalArticle

    Open Access
    2 Citations (Scopus)

    Platelet activation pathways are disrupted during acute anaphylaxis in humans

    McGrath, F., Woo, A., Fatovich, D., Arendts, G. & Bosio, E., Sep 2019, In : Internal Medicine Journal. 49, p. 17-17 1 p.

    Research output: Contribution to journalAbstract/Meeting Abstract

    Zfp281 (ZBP-99) plays a functionally redundant role with Zfp148 (ZBP-89) during erythroid development

    Woo, A., Patry, C-A. A., Ghamari, A., Pregernig, G., Yuan, D., Zheng, K., Piers, T., Hibbs, M., Li, J. K., Fidalgo, M., Wang, J. Y., Lee, J-H., Leedman, P., Wang, J., Fraenkel, E. & Cantor, A. B., 27 Aug 2019, In : Blood advances. 3, 16, p. 2499-2511 13 p.

    Research output: Contribution to journalArticle

    Open Access
  • Projects

    Prizes