Research Output per year
Personal profile
Biography
Dr Andrew J. Woo completed his Bachelor of Science with Honours and a Doctor of Philosophy in Biochemistry at The University of Western Australia in 2004. He then began his postdoctoral training under Dr. Alan B. Cantor’s mentorship at Children’s Hospital Boston / Dana-Faber Cancer Institute at Harvard Medical School, Boston, USA. Transcriptional gene regulation is the focus of his research and his discoveries contributed to the study of blood disorders, cancer and stem cell biology. He has published in many prestigious journals including, Cell, Journal of Clinical Investigation, Molecular Cell, Genes and Development, Nature Communications, Blood and Molecular & Cellular Biology. He has returned to Perth in 2012 with a fellowship from Royal Perth Hospital Medical Research Foundation.
Roles and responsibilities
Research approaches include.
- Protein-Protein Interaction identification via proteomics
- Protein-DNA interaction mapping via next generation sequencing techniques
- Transcriptomics by next generation sequencing techniques
- Functional genomics
- Transgenic Mouse Models
- Protein-Protein Interaction identification via proteomics
- Protein-DNA interaction mapping via next generation sequencing techniques
- Transcriptomics by next generation sequencing techniques
- Functional genomics
- Transgenic Mouse Models
Funding overview
2015 CIA, Cancer Council of Western Australia, Perth, Australia
2015 Sole CI, Medical Research Foundation WA, Perth, Australia
2014 Sole CI, Medical Research Foundation WA, Perth, Australia
2013 Sole CI, Medical Research Foundation WA, Perth, Australia
2012 Fellowship, Medical Research Foundation WA, Perth, Australia
2015 Sole CI, Medical Research Foundation WA, Perth, Australia
2014 Sole CI, Medical Research Foundation WA, Perth, Australia
2013 Sole CI, Medical Research Foundation WA, Perth, Australia
2012 Fellowship, Medical Research Foundation WA, Perth, Australia
Previous positions
Postdoctoral Research Fellow
Department of Hematology and Oncology
Boston Children's Hospital / Dana-Farber Cancer Institute,
Harvard Medical School,
Boston, MA, USA.
Department of Hematology and Oncology
Boston Children's Hospital / Dana-Farber Cancer Institute,
Harvard Medical School,
Boston, MA, USA.
Research
Dr Andrew Woo’s research interests encompass understanding the transcriptional gene regulatory mechanisms in stem/progenitors cells of blood and epithelial cancer stem cells. With Dr. Peter Leedman at Harry Perkins Institute of Medical Research, he also investigates the role of small non-coding RNA processing complexes in epithelial cancer onset and metastasis.
Languages
English and Korean
External positions
Lecturer and Unit Coordinator, Edith Cowan University
1 Jul 2018 → 2 Feb 2021Research expertise keywords
- Transcriptional gene regulation
- Stem cells and cancer
- Haematopoiesis and blood disorders
- Hormone-dependent cancers
- Protein-protein interaction
- Protein-DNA interaction
- Mouse genetics
- Bioinformatics
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Research Output
Targeting RSPO3-LGR4 Signaling for Leukemia Stem Cell Eradication in Acute Myeloid Leukemia
Salik, B., Yi, H., Hassan, N., Santiappillai, N., Vick, B., Connerty, P., Duly, A., Trahair, T., Woo, A. J., Beck, D., Liu, T., Spiekermann, K., Jeremias, I., Wang, J., Kavallaris, M., Haber, M., Norris, M. D., Liebermann, D. A., D'Andrea, R. J., Murriel, C. & 1 others, , 1 Jun 2020, In : Cancer Cell.Research output: Contribution to journal › Article
JMJD1C-mediated metabolic dysregulation contributes to HOXA9-dependent leukemogenesis
Lynch, J. R., Salik, B., Connerty, P., Vick, B., Leung, H., Pijning, A., Jeremias, I., Spiekermann, K., Trahair, T., Liu, T., Haber, M., Norris, M. D., Woo, A. J., Hogg, P., Wang, J. & Wang, J. Y., 8 Jan 2019, In : Leukemia. 33, 6, p. 1400-1410 11 p.Research output: Contribution to journal › Article
6
Citations
(Scopus)
MiR-101 suppresses the development of MLL-rearranged acute myeloid leukemia
Gonzales-Aloy, E., Connerty, P., Salik, B., Liu, B., Woo, A. J., Haber, M., Norris, M. D., Wang, J. & Wang, J. Y., Jul 2019, In : Haematologica. 104, 7, p. e296-e299 4 p.Research output: Contribution to journal › Article
Open Access
2
Citations
(Scopus)
Platelet activation pathways are disrupted during acute anaphylaxis in humans
McGrath, F., Woo, A., Fatovich, D., Arendts, G. & Bosio, E., Sep 2019, In : Internal Medicine Journal. 49, p. 17-17 1 p.Research output: Contribution to journal › Abstract/Meeting Abstract
Zfp281 (ZBP-99) plays a functionally redundant role with Zfp148 (ZBP-89) during erythroid development
Woo, A., Patry, C-A. A., Ghamari, A., Pregernig, G., Yuan, D., Zheng, K., Piers, T., Hibbs, M., Li, J. K., Fidalgo, M., Wang, J. Y., Lee, J-H., Leedman, P., Wang, J., Fraenkel, E. & Cantor, A. B., 27 Aug 2019, In : Blood advances. 3, 16, p. 2499-2511 13 p.Research output: Contribution to journal › Article
Open Access
Projects
- 5 Finished
Characterization of a new subtype of aggressive breast cancer
Blancafort, P., Redfern, A., Woo, A., Jain, M. & Curtis, C.
National Health & Medical Research Council NHMRC
1/01/17 → 31/12/19
Project: Research
Reprogramming metastatic tumours: Investigating the role of the ZBP family of transcription factors
Woo, A., Blancafort, P., Ram, R., Kim, J. & Wang, J.
1/01/16 → 31/12/16
Project: Research
Discovery and Characterisation of a Cancer Driver in a New Subtype of Agressive Breast Cancer
Blancafort, P., Redfern, A., Ingley, E., Woo, A., Taylor, N., Sorolla Bardaji, A. & Curtis, C.
1/01/16 → 31/12/16
Project: Research