Andrew Whitehouse

Professor, BSc Curtin, PhD W.Aust., Head, Autism Research Team, Telethon Kids Institute, Director, CliniKids, Telethon Kids Institute, Program Head, Disability, Telethon Kids Institute, Chief Research Officer, Autism CRC

  • The University of Western Australia (M560), 35 Stirling Highway,

    6009 Perth

    Australia

  • 4182 Citations
  • 36 h-Index
20052021
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Research Output 2005 2019

3 Citations (Scopus)

Atypical nested 22q11.2 duplications between LCR22B and LCR22D are associated with neurodevelopmental phenotypes including autism spectrum disorder with incomplete penetrance

Woodward, K. J., Stampalia, J., Vanyai, H., Rijhumal, H., Potts, K., Taylor, F., Peverall, J., Grumball, T., Sivamoorthy, S., Alinejad-Rokny, H., Wray, J., Whitehouse, A., Nagarajan, L., Scurlock, J., Afchani, S., Edwards, M., Murch, A., Beilby, J., Baynam, G., Kiraly-Borri, C. & 2 othersMcKenzie, F. & Heng, J. I. T., Feb 2019, In : Molecular genetics & genomic medicine. 7, 2, 17 p., 507.

Research output: Contribution to journalArticle

Open Access
171 Downloads (Pure)

Brief social attention bias modification for children with autism spectrum disorder

Alvares, G. A., Chen, N. T. M., Notebaert, L., Granich, J., Mitchell, C. & Whitehouse, A. J. O., 10 Jan 2019, In : Autism Research. p. 527-535

Research output: Contribution to journalArticle

File
Autism Spectrum Disorder
Control Groups
Attention Deficit Disorder with Hyperactivity
Autistic Disorder
Differential Diagnosis
5 Citations (Scopus)

Characterizing the interplay between autism spectrum disorder and comorbid medical conditions: An integrative review

Tye, C., Runicles, A. K., Whitehouse, A. J. O. & Alvares, G. A., 23 Jan 2019, In : Frontiers in Psychiatry. 9, 751.

Research output: Contribution to journalReview article

Open Access
Comorbidity
Epilepsy
Sleep
Biomarkers
Autism Spectrum Disorder

Content validation of the Quality of Life Inventory—Disability

Epstein, A., Williams, K., Reddihough, D., Murphy, N., Leonard, H., Whitehouse, A., Jacoby, P. & Downs, J., 1 Jan 2019, In : Child: Care, Health and Development. 45, 5, p. 654-659 6 p.

Research output: Contribution to journalArticle

Disabled Children
Intellectual Disability
Quality of Life
Caregivers
Interviews
1 Citation (Scopus)

Developmental vitamin D deficiency produces behavioral phenotypes of relevance to Autism in an animal model

Ali, A., Vasileva, S., Langguth, M., Alexander, S., Cui, X., Whitehouse, A., McGrath, J. J. & Eyles, D., 1 May 2019, In : Nutrients. 11, 5, 1187.

Research output: Contribution to journalArticle

Open Access
vitamin D deficiency
Vitamin D Deficiency
Autistic Disorder
vitamin D
Vitamin D
119 Citations (Scopus)

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

23andMe Research Team, ADHD Working Group of the Psychiatric Genomics Consortium (PGC) & Early Lifecourse & Genetic Epidemiology (EAGLE) Consortium, 1 Jan 2019, In : Nature Genetics. 51, 1, p. 63-75 13 p.

Research output: Contribution to journalArticle

Attention Deficit Disorder with Hyperactivity
Genome
Genome-Wide Association Study
Meta-Analysis
Population
1 Citation (Scopus)

Effect of Fluoxetine on Obsessive-Compulsive Behaviors in Children and Adolescents With Autism Spectrum Disorders: A Randomized Clinical Trial

Reddihough, D. S., Marraffa, C., Mouti, A., O'Sullivan, M., Lee, K. J., Orsini, F., Hazell, P., Granich, J., Whitehouse, A. J. O., Wray, J., Dossetor, D., Santosh, P., Silove, N. & Kohn, M., 22 Oct 2019, In : JAMA. 322, 16, p. 1561-1569 9 p.

Research output: Contribution to journalArticle

Compulsive Behavior
Obsessive Behavior
Fluoxetine
Randomized Controlled Trials
Placebos

Examining parent use of specific intervention techniques during a 12-week training program based on the Early Start Denver Model

Waddington, H., van der Meer, L., Sigafoos, J. & Whitehouse, A., 2019, (Accepted/In press) In : Autism.

Research output: Contribution to journalArticle

Education
Parents
Mothers
Language
Autistic Disorder

Gaps in Current Autism Research: The Thoughts of the Autism Research Editorial Board and Associate Editors

Amaral, D. G., Anderson, G. M., Bailey, A., Bernier, R., Bishop, S., Blatt, G., Canal-Bedia, R., Charman, T., Dawson, G., de Vries, P. J., Dicicco-Bloom, E., Dissanayake, C., Kamio, Y., Kana, R., Khan, N. Z., Knoll, A., Kooy, F., Lainhart, J., Levitt, P., Loveland, K. & 11 othersMinshew, N., Mueller, R-A., Murphy, D., Mundy, P., Palencia, S., Pinto-Martin, J., Rattazzi, A., Rogers, S., Stone, W. L., Webb, S. J. & Whitehouse, A., May 2019, In : Autism Research. 12, 5, p. 700-714 15 p.

Research output: Contribution to journalEditorial

Genome-wide association meta-analysis of autistic traits in the general population

Bralten, J., Cadby, G., Jones, R., Whitehouse, A., Moses, E., Shumskaya, E., Buitelaar, J., Franke, B. & Poelmans, G., 2019, In : European Neuropsychopharmacology. 29, p. S754-S754 1 p.

Research output: Contribution to journalAbstract/Meeting Abstract

Facial Asymmetry
Autistic Disorder
Research
Siblings
Brain
1 Citation (Scopus)
196 Downloads (Pure)

Maternal pre-pregnancy weight and autistic-like traits among offspring in the general population

Varcin, K. J., Newnham, J. P. & Whitehouse, A. J. O., Jan 2019, In : Autism Research. 12, 1, p. 80-88 9 p.

Research output: Contribution to journalArticle

Open Access
File
Mothers
Weights and Measures
Pregnancy
Autistic Disorder
Population
1 Citation (Scopus)

Parental experiences using the Therapy Outcomes by You (TOBY) application to deliver early intervention to their child with autism

Rogerson, J., Falkmer, M., Cuomo, B., Falkmer, T., Whitehouse, A. J. O., Granich, J. & Vaz, S., 19 May 2019, In : Developmental Neurorehabilitation. 22, 4, p. 219-227 9 p.

Research output: Contribution to journalArticle

Autistic Disorder
Parents
Therapeutics
Child Development
Secondary Prevention
3 Citations (Scopus)

Pre-emptive intervention versus treatment as usual for infants showing early behavioural risk signs of autism spectrum disorder: a single-blind, randomised controlled trial

Whitehouse, A. J. O., Varcin, K. J., Alvares, G. A., Barbaro, J., Bent, C., Boutrus, M., Chetcuti, L., Cooper, M. N., Clark, A., Davidson, E., Dimov, S., Dissanayake, C., Doyle, J., Grant, M., Iacono, T., Maybery, M., Pillar, S., Renton, M., Rowbottam, C., Sadka, N. & 8 othersSegal, L., Slonims, V., Taylor, C., Wakeling, S., Wan, M. W., Wray, J., Green, J. & Hudry, K., Sep 2019, In : The Lancet Child & Adolescent Health. 3, 9, p. 605-615

Research output: Contribution to journalArticle

Randomized Controlled Trials
Caregivers
Therapeutics
Parenting
Autistic Disorder

Prevalence of Motor Difficulties in Autism Spectrum Disorder: Analysis of a Population-Based Cohort

Licari, M. K., Alvares, G. A., Varcin, K., Evans, K. L., Cleary, D., Reid, S. L., Glasson, E. J., Bebbington, K., Reynolds, J. E., Wray, J. & Whitehouse, A. J. O., 18 Oct 2019, In : Autism Research.

Research output: Contribution to journalArticle

Autistic Disorder
Spectrum Analysis
Population
Socialization
Autism Spectrum Disorder
3 Citations (Scopus)

Psychometric properties of the Quality of Life Inventory-Disability (QI-Disability) measure

Downs, J., Jacoby, P., Leonard, H., Epstein, A., Murphy, N., Davis, E., Reddihough, D., Whitehouse, A. & Williams, K., 15 Mar 2019, In : Quality of Life Research. 28, 3, p. 783-794 12 p.

Research output: Contribution to journalArticle

Psychometrics
Quality of Life
Intellectual Disability
Equipment and Supplies
Leisure Activities
Femininity
Masculinity
Population
Autistic Disorder
Testosterone

Sleep problems and anxiety from 2 to 8 years and the influence of autistic traits: a longitudinal study

Uren, J., Richdale, A. L., Cotton, S. M. & Whitehouse, A. J. O., 19 Jan 2019, In : European Child and Adolescent Psychiatry. 11 p.

Research output: Contribution to journalArticle

Longitudinal Studies
Sleep
Anxiety
Demography
Pregnancy

The Brain Basis of Comorbidity in Neurodevelopmental Disorders

Licari, M. K., Finlay-Jones, A., Reynolds, J. E., Alvares, G. A., Spittle, A. J., Downs, J., Whitehouse, A. J. O., Leonard, H., Evans, K. L. & Varcin, K., Mar 2019, In : Current Developmental Disorders Reports. 6, 1, p. 9-18 10 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

The misnomer of ‘high functioning autism’: Intelligence is an imprecise predictor of functional abilities at diagnosis

Alvares, G. A., Bebbington, K., Cleary, D., Evans, K., Glasson, E. J., Maybery, M. T., Pillar, S., Uljarević, M., Varcin, K., Wray, J. & Whitehouse, A. J. O., 19 Jun 2019, In : Autism.

Research output: Contribution to journalArticle

Aptitude
Autistic Disorder
Intelligence
Psychological Adaptation
Intellectual Disability

‘Everyone gets a kick’: Coach characteristics and approaches to inclusion in an Australian Rules Football program for children

May, T., Sivaratnam, C., Williams, K., McGillivray, J., Whitehouse, A. & Rinehart, N. J., 1 Oct 2019, In : International Journal of Sports Science and Coaching. 14, 5, p. 607-616 10 p.

Research output: Contribution to journalArticle

coach
inclusion
disability
physical disability
coaching
2018

A National Guideline for the Assessment and Diagnosis of Autism Spectrum Disorder in Australia

Whitehouse, A., Evans, K., Eapen, V. & Wray, J., 2018, Australia: Autism CRC.

Research output: Book/ReportOther output

7 Citations (Scopus)

An integrative analysis of non-coding regulatory DNA variations associated with autism spectrum disorder

Williams, S. M., An, J. Y., Edson, J., Watts, M., Murigneux, V., Whitehouse, A. J. O., Jackson, C. J., Bellgrove, M. A., Cristino, A. S. & Claudianos, C., 27 Apr 2018, In : Molecular Psychiatry. p. 1-13 13 p.

Research output: Contribution to journalArticle

Open Access
DNA
Nucleotides
Genes
Nucleic Acid Regulatory Sequences
MicroRNAs
2 Citations (Scopus)
177 Downloads (Pure)

A prospective study of fetal head growth, autistic traits and autism spectrum disorder

Blanken, L. M. E., Dass, A., Alvares, G., van der Ende, J., Schoemaker, N. K., El Marroun, H., Hickey, M., Pennell, C., White, S., Maybery, M. T., Dissanayake, C., Jaddoe, V. W. V., Verhulst, F. C., Tiemeier, H., McIntosh, W., White, T. & Whitehouse, A., Apr 2018, In : Autism Research. 11, 4, p. 602-612 11 p.

Research output: Contribution to journalArticle

Open Access
File
Otitis Media
Cohort Studies
Pregnancy
Child Behavior
Checklist
4 Citations (Scopus)

Does perinatal exposure to exogenous oxytocin influence child behavioural problems and autistic-like behaviours to 20 years of age?

Guastella, A. J., Cooper, M. N., White, C. R. H., White, M. K., Pennell, C. E. & Whitehouse, A. J. O., 1 Dec 2018, In : Journal of Child Psychology and Psychiatry and Allied Disciplines. 59, 12, p. 1323-1332 10 p.

Research output: Contribution to journalArticle

Oxytocin
Child Behavior
Parturition
Autistic Disorder
Mental Health

No relationship between autistic traits and salivary testosterone concentrations in men from the general population

Tan, D. W., Maybery, M., Clarke, M., Di Lorenzo, R., Evans, M., Mancinone, M., Panos, C. & Whitehouse, A., 14 Jun 2018, In : PLoS One. 13, 6, e0198779.

Research output: Contribution to journalArticle

Open Access
testosterone
Testosterone
Population
Autistic Disorder
college students
1 Citation (Scopus)

Predicting language difficulties in middle childhood from early developmental milestones: A comparison of traditional regression and machine learning techniques

Armstrong, R., Symons, M., Scott, J. G., Arnott, W. L., Copland, D. A., McMahon, K. L. & Whitehouse, A. J. O., 1 Aug 2018, In : Journal of Speech, Language, and Hearing Research. 61, 8, p. 1926-1944 19 p.

Research output: Contribution to journalArticle

Language
childhood
regression
Logistic Models
Aptitude
11 Citations (Scopus)

Social impairments in autism spectrum disorder are related to maternal immune history profile

Patel, S., Masi, A., Dale, R. C., Whitehouse, A. J. O., Pokorski, I., Alvares, G. A., Hickie, I. B., Breen, E. & Guastella, A. J., 1 Aug 2018, In : Molecular Psychiatry. 23, 8, p. 1794-1797 4 p.

Research output: Contribution to journalArticle

Open Access
History
Mothers
Immune System
Cohort Effect
Pregnancy
1 Citation (Scopus)

Study protocol for the Australian autism biobank: an international resource to advance autism discovery research

Australian Autism Biobank Team, 27 Aug 2018, In : BMC Pediatrics. 18, 9 p., 284.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
Open Access
Nausea
Vomiting
Case-Control Studies
Pregnancy
Communication
15 Citations (Scopus)

The prevalence of mental health disorders and symptoms in children and adolescents with cerebral palsy: a systematic review and meta-analysis

Downs, J., Blackmore, A. M., Epstein, A., Skoss, R., Langdon, K., Jacoby, P., Whitehouse, A. J. O., Leonard, H., Rowe, P. W., Glasson, E. J. & The Cerebral Palsy Mental Health Group, 1 Jan 2018, In : Developmental Medicine and Child Neurology. 60, 1, p. 30-38 9 p.

Research output: Contribution to journalReview article

Cerebral Palsy
Mental Disorders
Meta-Analysis
Mental Health
Confidence Intervals
6 Citations (Scopus)

Vitamin D is crucial for maternal care and offspring social behaviour in rats

Yates, N. J., Tesic, D., Feindel, K. W., Smith, J. T., Clarke, M. W., Wale, C., Crew, R. C., Wharfe, M. D., Whitehouse, A. J. & Wyrwoll, C. S., 1 May 2018, In : Journal of Endocrinology. 237, 2, p. 73-85 13 p.

Research output: Contribution to journalArticle

Social Behavior
Vitamin D
Mothers
Grooming
Vitamin D Deficiency
2017
7 Citations (Scopus)
Open Access
Psychotic Disorders
Schizophrenia
Mothers
Population
International Classification of Diseases
1 Citation (Scopus)

Acoustic properties of cries in 12-month old infants at high-risk of Autism Spectrum Disorder

Unwin, L. M., Bruz, I., Maybery, M. T., Reynolds, V., Ciccone, N., Dissanayake, C., Hickey, M. & Whitehouse, A. J. O., Jul 2017, In : Journal of Autism and Developmental Disorders. 47, 7, p. 2108-2119 12 p.

Research output: Contribution to journalArticle

Acoustics
Siblings
Phonation
Prospective Studies
Autism Spectrum Disorder
10 Citations (Scopus)

A randomised controlled trial of an iPad-based application to complement early behavioural intervention in Autism Spectrum Disorder

Whitehouse, A., Granich, J., Alvares, G., Busacca, M., Cooper, M., Dass, A., Duong, T., Harper, R., Marshall, W., Richdale, A., Rodwell, T., Trembath, D., Vellanki, P., Moore, D. & Anderson, A., Sep 2017, In : Journal of Child Psychology and Psychiatry. 58, 9, p. 1042–1052 11 p.

Research output: Contribution to journalArticle

Randomized Controlled Trials
Learning
Technology
Therapeutics
Autistic Disorder
1 Citation (Scopus)

A Relationship Between Early Language Skills and Adult Autistic-Like Traits: Evidence from a Longitudinal Population-Based Study

Armstrong, R., Whitehouse, A. J. O., Scott, J. G., Copland, D. A., McMahon, K. L., Fleming, S. & Arnott, W., May 2017, In : Journal of Autism and Developmental Disorders. 47, 5, p. 1478-1489 12 p.

Research output: Contribution to journalArticle

Aptitude
Language
Autistic Disorder
Communication
Population
21 Citations (Scopus)
234 Downloads (Pure)

Beyond the hype and hope: Critical considerations for intranasal oxytocin research in autism spectrum disorder

Alvares, G. A., Quintana, D. S. & Whitehouse, A. J. O., 1 Jan 2017, In : Autism Research. 10, 1, p. 25-41 17 p.

Research output: Contribution to journalReview article

Open Access
File
Hope
Oxytocin
Research
Nasal Sprays
Autistic Disorder
1 Citation (Scopus)

Brief report: An exploratory study of the diagnostic reliability for Autism Spectrum Disorder

Taylor, L. J., Eapen, V., Maybery, M., Midford, S., Paynter, J., Quarmby, L., Smith, T., Williams, K. & Whitehouse, A. J. O., May 2017, In : Journal of Autism and Developmental Disorders. 47, 5, p. 1551-1558 8 p.

Research output: Contribution to journalArticle

Surgical Instruments
Video Recording
Autistic Disorder
Appointments and Schedules
Observation
13 Citations (Scopus)

Cytokine levels and associations with symptom severity in male and female children with autism spectrum disorder

Masi, A., Breen, E. J., Alvares, G. A., Glozier, N., Hickie, I. B., Hunt, A., Hui, J., Beilby, J., Ravine, D., Wray, J., Whitehouse, A. J. O. & Guastella, A. J., 2 Dec 2017, In : Molecular Autism. 8, 1, 63.

Research output: Contribution to journalArticle

Open Access
Cytokines
Immune System
Autism Spectrum Disorder
Interleukin-8
Interleukin-1
16 Citations (Scopus)

Duration of general anaesthetic exposure in early childhood and long-term language and cognitive ability

Ing, C., Hegarty, M. K., Perkins, J. W., Whitehouse, A. J. O., DiMaggio, C. J., Sun, M., Andrews, H., Li, G., Sun, L. S. & von Ungern-Sternberg, B. S., Sep 2017, In : British Journal of Anaesthesia. 119, 3, p. 532-540 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
144 Downloads (Pure)
Open Access
File
Critical Pathways
Behavioral Symptoms
Delayed Diagnosis
Therapeutics
Autism Spectrum Disorder
7 Citations (Scopus)
240 Downloads (Pure)

Evidence of a reduction over time in the behavioral severity of autistic disorder diagnoses

Whitehouse, A. J. O., Cooper, M. N., Bebbington, K., Alvares, G., Lin, A., Wray, J. & Glasson, E. J., 19 Jan 2017, In : Autism Research. 10, 1, p. 179-187 9 p.

Research output: Contribution to journalArticle

Open Access
File
Autistic Disorder
Phenotype
Behavioral Symptoms
Western Australia
Linear Models
8 Citations (Scopus)

Exploring quality of life of children with cerebral palsy and intellectual disability: What are the important domains of life?

Davis, E., Reddihough, D., Murphy, N., Epstein, A., Reid, S. M., Whitehouse, A., Williams, K., Leonard, H. & Downs, J., 1 Nov 2017, In : Child: Care, Health and Development. 43, 6, p. 854-860 7 p.

Research output: Contribution to journalArticle

Cerebral Palsy
Intellectual Disability
Quality of Life
Communication
Interviews
5 Citations (Scopus)
Open Access
Masculinity
Photogrammetry
Communication
Femininity
Autistic Disorder
1 Citation (Scopus)

Investigating facial phenotype in autism spectrum conditions: The importance of a hypothesis driven approach

Boutrus, M., Maybery, M. T., Alvares, G. A., Tan, D. W., Varcin, K. J. & Whitehouse, A. J. O., 1 Dec 2017, In : Autism Research. 10, 12, p. 1910-1918 9 p.

Research output: Contribution to journalComment/debate

Autistic Disorder
Phenotype
Facial Asymmetry
Developmental Disabilities
Research
3 Citations (Scopus)

Late talkers and later language outcomes: Predicting the different language trajectories

Armstrong, R., Scott, J. G., Whitehouse, A. J. O., Copland, D. A., McMahon, K. L. & Arnott, W., 4 May 2017, In : International Journal of Speech-Language Pathology. 19, 3, p. 237-250 14 p.

Research output: Contribution to journalArticle

Language
Mothers
Pregnancy
Western Australia
Language Development
5 Citations (Scopus)
137 Downloads (Pure)

Parent-observed thematic data on quality of life in children with autism spectrum disorder

Epstein, A., Whitehouse, A., Williams, K., Murphy, N., Leonard, H., Davis, E., Reddihough, D. & Downs, J., 26 Oct 2017, In : Autism.

Research output: Contribution to journalArticle

Open Access
File
Quality of Life
Fathers
Intellectual Disability
Population
Parents