• The University of Western Australia (M504), 35 Stirling Highway,

    6009 Perth

    Australia

Calculated based on number of publications stored in Pure and citations from Scopus

Personal profile

Biography

Dr. Alfred Chin Yen Tay embarked on his academic journey, culminating in a PhD degree from UNSW in 2010. Since then, he has played pivotal roles as a research associate and laboratory manager at the Helicobacter Research Laboratory within the UWA Marshall Centre for Infectious Diseases Research and Training. Dr. Tay's research passions lie in the realms of antibiotic resistance and the genetic intricacies of Helicobacter pylori (H. pylori). Collaborating closely with Nobel Laureate Prof. Barry Marshall, he has diligently monitored antibiotic resistance trends among the Western Australian populace. Furthermore, Dr. Tay has been granted the opportunity to sequence and scrutinize the genomes of these antibiotic-resistant strains, unraveling their genomic architecture and pathogenic potential.

In parallel, armed with advanced Next Generation Sequencing analytical skills, Dr. Tay leads a team dedicated to identifying alternative genomic markers. Their objective is to redefine Helicobacter as a species and gain insights into the evolutionary path that transformed Helicobacter into a human pathogen. Dr. Tay's commitment to the scientific community extends to his role as the current webmaster of www.helico.com. Beyond website maintenance and upgrades, he actively engages in daily forum interactions, disseminating comprehensive information about H. pylori to individuals worldwide.

Dr. Chin Yen Tay's prominence as a distinguished researcher stems from his significant contributions to clinical research, with a focus on H. pylori, genomics, and the application of cutting-edge next-generation sequencing technology. Over the past five years, Dr. Tay's impactful investigations into the antibiotic resistance profiles of H. pylori within Western Australia have paved the way for personalized treatment strategies. His work in antibiotic susceptibility testing has yielded an impressive cure rate of over 95% for multi-drug resistant cases.

Dr. Tay's dedication extends to combating H. pylori infection, especially in China, where antibiotic resistance poses a formidable challenge. His efforts have been bolstered by a grant from Shenzhen Dapeng Hospital in 2017, which propelled the development of advanced H. pylori research capabilities. Under his guidance, the hospital has emerged as a leader in H. pylori cultivation and the effective treatment of antibiotic-resistant cases.

In addition to these accomplishments, Dr. Tay has forged robust collaborations with esteemed institutions such as Shenzhen University, Guizhou Medical University, Sichuan University, and Zhengzhou University. These partnerships have amplified the global reach of his research initiatives. Furthermore, his visionary initiatives have transcended international boundaries. Supported by the Department of Foreign Affairs and Trading (DFAT), he established the Australia-China Helicobacter Fellowship Training Program, facilitating knowledge exchange and international research partnerships with scholars from across China.

Dr. Tay's extensive research network spans the globe and encompasses collaborations with prominent researchers like Dr. Annemieke Smet from the University of Antwerp (Belgium), Dr. Mamatha Ballal from Kasturba Medical College (India), Dr. Nidhi Chauhan from Amity University (India), and Prof. Jamuna Vadivelu from the University Malaya (Malaysia). These collaborations have culminated in the publication of at least one peer-reviewed scientific article each year.

In conclusion, Dr. Chin Yen Tay is a distinguished researcher with a diverse array of research interests and a rich tapestry of collaborations in the realm of microbiota research, with a specific focus on H. pylori. His unwavering commitment to advancing our understanding of H. pylori infection has significantly enhanced both knowledge and treatment strategies, particularly in regions grappling with high incidences of gastric cancer.

Roles and responsibilities

Manager of Helicobacter Research Laboratory

Project manager of Helicobacter Research

Project manager of next generation sequencing projects

Helicobacter pylori research training

 

Research

Population genetic of Helicobacter pylori

Antibiotic resistance surveillance in Helicobacter pylori

Evolution of Helicobacter spp

Screening and testing of novel anti-Helicobacter compound

General microbiota analysis 

Languages

Mandarin
English

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 14 - Life Below Water

Education/Academic qualification

Microbiology, PhD, Population structure of Helicobacter pylori, University of New South Wales

Award Date: 1 Nov 2010

Research expertise keywords

  • Helicobacter pylori research
  • Molecular microbiology
  • Genomic DNA microarray
  • Population structure analysis
  • Bioinformatics

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