• The University of Western Australia (M504), 35 Stirling Highway, Room 2.04 and 2.02, L Block, QEII Medical Centre

    6009 Perth

    Australia

  • The University of Western Australia (M519), 35 Stirling Highway, Room 2.04 and 2.02, L Block, QEII Medical Centre

    6009 Perth

    Australia

  • 334 Citations
  • 11 h-Index
19962021
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Personal profile

Biography

Dr Alec Redwood completed a Bachelor of Applied Science with Honours and a PhD researching cytokine responses to fungal infections at Curtin University. He then worked as a Research Assistant for Dr Bruce Robinson in the Department of Medicine before being awarded a Fellowship with the School of Oral Health Sciences at UWA. Dr Redwood became involved in the Pest Animal Control Cooperative Research Centre researching the use of murine cytomegalovirus (MCMV) as a vaccine vector for virally vectored immunocontraception. Since 2005 he has been studying various aspects of the fundamental biology of MCMV.

Roles and responsibilities

Dr Redwood is the coordinating supervisor of 3 PhD students and the co-supervisor of another 1 PhD student.

Funding overview

NH&MRC

Teaching overview

Dr Redwood lectures on viral immune evasion in the Masters of Infectious Diseases unit. He also supervises Visnja Madic (PhD), Jackie Robb and Baca Chan (PhD).

Research

Dr Redwood is interested in understanding the interactions between viruses and their hosts, especially how viral genetics control their responses to the host, and how host genetics control their response to the virus. He is currently researching MCMV a common a herpesvirus found in mice that is used as a model for the human equivalent virus. Because most hosts are infected with multiple strains of MCMV Dr Redwood is studying how these strains associate with each other and how this association affects viral pathogenesis.

Keywords

  • Immunology—cellular
  • Viruses—BACs
  • Viruses—herpes
  • Viruses—vaccines

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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mice Agriculture & Biology
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Projects 2003 2021

Research Output 1996 2017

6 Citations

Shared peptide binding of HLA Class i and II alleles associate with cutaneous nevirapine hypersensitivity and identify novel risk allele

Pavlos, R. , McKinnon, E. J. , Ostrov, D. A. , Peters, B. , Buus, S. , Koelle, D. , Chopra, A. , Schutte, R. , Rive, C. , Redwood, A. , Restrepo, S. , Bracey, A. , Kaever, T. , Myers, P. , Speers, E. , Malaker, S. A. , Shabanowitz, J. , Jing, Y. , Gaudieri, S. , Hunt, D. F. & 4 others Carrington, M., Haas, D. W., Mallal, S. & Phillips, E. J., 1 Dec 2017, In : Scientific Reports. 7, 1, 8653

Research output: Contribution to journalArticle

Open Access
Nevirapine
HLA Antigens
Hypersensitivity
Alleles
Skin
1 Citations
Open Access
Muromegalovirus
Cytomegalovirus
Salivary Glands
Genetic Recombination
Infection
14 Citations

Inhibition of the TRAIL Death Receptor by CMV Reveals Its Importance in NK Cell-Mediated Antiviral Defense

Verma, S., Loewendorf, A., Wang, Q., Mcdonald, B., Redwood, A. & Benedict, C. A., 2014, In : PLoS Pathogens. 10, p. 1-11

Research output: Contribution to journalArticle

Molecular Evolution of Murine Cytomegalovirus Genomes

Redwood, A., Shellam, G. & Smith, L., 2013, Cytomegaloviruses: From Molecular Pathogenesis to Intervention. Reddehase, M. J. (ed.). UK: Caister Academic Press, p. 23-38

Research output: Chapter in Book/Conference paperOther chapter contribution

15 Citations

Natural killer cell dependent within-host competition arises during multiple MCMV infection: Consequences for viral transmission and evolution

McWhorter, A., Smith, L., Masters, L., Chan, B. C., Shellam, G. & Redwood, A., 2013, In : PLoS Pathogens. 9, 1, p. 13pp

Research output: Contribution to journalArticle

Open Access
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