Research output per year
Research output per year
Personal profile
Biography
Ms Brown is a passionate young scientist who has extensive experience in studying the complexities of some of the most aggressive and less well characterized cancers. Ms Brown completed a Bachelor of Health Science at UWA (2010), followed by Bachelor of Medical Science (Honours) at UWA in 2012 through the School of Pharmacology. She is an established research officer, who is now in her final year of completing her PhD studies in head and neck cancer. Since joining the Laboratory for Cancer Medicine at the Harry Perkins Instutute of Medical Research, under the supervision of Prof Peter Leedman, she has contributed to many projects and published a number of research articles, reviews and a book chapter in the field of cancer biology. Her main project focus is investigating the roles of microRNAs in cancer biology and evaluating their therapeutic potential for treatment of poor-prognostic cancers.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research expertise keywords
- Cancer
- Cancer Biology
- Drug delivery
- Resistance mechanisms
- therapeutics
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Investigating the roles of microRNA-7-5p in head and neck squamous cell carcinoma and response to chemotherapy
Brown, R., 2024, (Unpublished) 179 p.Research output: Thesis › Doctoral Thesis
File98 Downloads (Pure) -
The tumor suppressor miR-642a-5p targets Wilms Tumor 1 gene and cell-cycle progression in prostate cancer
Beveridge, D. J., Richardson, K. L., Epis, M. R., Brown, R. A. M., Stuart, L. M., Woo, A. J. & Leedman, P. J., Dec 2021, In: Scientific Reports. 11, 1, 18003.Research output: Contribution to journal › Article › peer-review
Open Access16 Citations (Scopus) -
Altered Iron Metabolism and Impact in Cancer Biology, Metastasis, and Immunology
Brown, R. A. M., Richardson, K. L., Kabir, T. D., Trinder, D., Ganss, R. & Leedman, P. J., 9 Apr 2020, In: Frontiers in Oncology. 10, 476.Research output: Contribution to journal › Review article › peer-review
Open Access172 Citations (Scopus) -
A microRNA-7/growth arrest specific 6/TYRO3 axis regulates the growth and invasiveness of sorafenib-resistant cells in human hepatocellular carcinoma
Kabir, T. D., Ganda, C., Brown, R. M., Beveridge, D. J., Richardson, K. L., Chaturvedi, V., Candy, P., Epis, M., Wintle, L., Kalinowski, F., Kopp, C., Stuart, L. M., Yeoh, G. C., George, J. & Leedman, P. J., 1 Jan 2018, In: Hepatology. 67, 1, p. 216-231 16 p.Research output: Contribution to journal › Article › peer-review
103 Citations (Scopus) -
Evaluation of microRNA delivery in vivo
Brown, R. A. M., Richardson, K. L., Kalinowski, F. C., Epis, M. R., Horsham, J. L., Kabir, T. D., De Pinho, M. H., Beveridge, D. J., Stuart, L. M., Wintle, L. C. & Leedman, P. J., 2018, MicroRNA and Cancer: Methods and Protocols. Wu, W. (ed.). 2nd ed. Humana Press Inc., Vol. 1699. p. 155-178 24 p. (Methods in Molecular Biology; vol. 1699).Research output: Chapter in Book/Conference paper › Chapter › peer-review
14 Citations (Scopus)
Projects
- 1 Active
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A new RNA-based therapeutic for oral cancer
Leedman, P. (Investigator 01), Flukes, S. (Investigator 02), Brown, R. (Investigator 03) & Cullis, P. (Investigator 04)
NHMRC National Health and Medical Research Council
1/03/24 → 29/02/28
Project: Research