Research output per year
Research output per year
Personal profile
Biography
I graduated with a BSc(Hons) from the University of Western Australia. I completed my PhD at UWA where I used passive immunotherapy to prevent influenza infection. After completing my PhD I researched the role of the immune system in cancer treatment and gained extensive experience with high-parameter flow cytometry.
I joined the Centre for Microscopy, Characterisation and Analysis (CMCA) in 2019 as the platform leader for flow cytometry. I oversee the operation and development of research projects and train users on flow cytometry instruments including analysers (BD FACS Canto II and BD LSR Fortessa), cell sorters (BD FACSMelody and BD Influx), cell picking (ALS CellCelector), multiplexing assays (Luminex) and mass cytometry (CyTOF).
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Prevention of influenza virus infection using ruminant polyclonal antibodies and the impact on the host immune response, The University of Western Australia
Award Date: 9 Oct 2015
Research expertise keywords
- Flow cytometry
- Flow cytometry (FACS—fluorescence activated cell sorting)
- Mass Cytometry
- Single Cell Isolation
- Multiplex cytometry bead assay
- Multiplex Analysis
- Flow cytometry analysis
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Geldanamycin treatment does not result in anti-cancer activity in a preclinical model of orthotopic mesothelioma
Orozco Morales, M. L., Rinaldi, C. A., de Jong, E., Lansley, S. M., Lee, Y. C. G., Zemek, R. M., Bosco, A., Lake, R. A. & Lesterhuis, W. J., May 2023, In: PLoS One. 18, 5, e0274364.Research output: Contribution to journal › Article › peer-review
Open Access -
Plasma cell but not CD20-mediated B cell depletion protects from bleomycin-induced lung fibrosis
Prêle, C. M., Miles, T., Pearce, D. R., O'Donoghue, R. J., Grainge, C., Barrett, L., Birnie, K., Lucas, A. D., Baltic, S., Ernst, M., Rinaldi, C., Laurent, G. J., Knight, D. A., Fear, M., Hoyne, G., McAnulty, R. J. & Mutsaers, S. E., 1 Nov 2022, In: The European Respiratory Journal. 60, 5, 2101469.Research output: Contribution to journal › Article › peer-review
Open AccessFile36 Citations (Scopus)66 Downloads (Pure) -
PPARα and PPARγ activation is associated with pleural mesothelioma invasion but therapeutic inhibition is ineffective
Orozco Morales, M. L., Rinaldi, C. A., de Jong, E., Lansley, S. M., Gummer, J. P. A., Olasz, B., Nambiar, S., Hope, D. E., Casey, T. H., Lee, Y. C. G., Leslie, C., Nealon, G., Shackleford, D. M., Powell, A. K., Grimaldi, M., Balaguer, P., Zemek, R. M., Bosco, A., Piggott, M. J. & Vrielink, A. & 2 others, , 21 Jan 2022, In: Iscience. 25, 1, 103571.Research output: Contribution to journal › Article › peer-review
Open Access9 Citations (Web of Science) -
Preventing chemotherapy-induced myelosuppression by repurposing the FLT3 inhibitor quizartinib
Taylor, S., Duyvestyn, J., Zeps, S., Dishington, E., Rinaldi, C., Dovey, O. M., Vassiliou, G., Grove, C. & Langdon, W., 9 Aug 2017, In: Science Translational Medicine. 9, 402, 14 p., aam8060.Research output: Contribution to journal › Article › peer-review
37 Citations (Scopus) -
Identification of repurposed drugs that increase immune checkpoint blockade efficacy in cancer using network analysis of responding tumours
Zemek, R., Rinaldi, C., Millward, M., Nowak, A. K., Bosco, A., Lake, R. & Lesterhuis, W. J., Aug 2016, In: European Journal of Immunology. 46, p. 576-576 1 p.Research output: Contribution to journal › Abstract/Meeting Abstract › peer-review
Projects
- 2 Finished
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Characterising deleterious changes in tumour macrophage behaviour during breast cancer progression
Pixley, F. (Chief Investigator), Ellies, L. (Investigator 02) & Rinaldi, C. (Investigator 03)
The University of Western Australia
1/01/20 → 30/04/22
Project: Research
Equipment
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10x Chromium Genomics Platform
Centre for Microscopy, Characterisation & AnalysisFacility/equipment: Equipment
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BD Influx cell sorter
Centre for Microscopy, Characterisation & AnalysisFacility/equipment: Equipment
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