Research Output 1990 2019

Filter
Article
2016
25 Citations (Scopus)

Targeting CBLB as a potential therapeutic approach for disseminated candidiasis

Xiao, Y., Tang, J., Guo, H., Zhao, Y., Tang, R., Ouyang, S., Zeng, Q., Rappleye, C. A., Rajaram, M. V. S., Schlesinger, L. S., Tao, L., Brown, G. D., Langdon, W. Y., Li, B. T. & Zhang, J., 2016, In : Nature Medicine. 22, 8, p. 906-914 9 p.

Research output: Contribution to journalArticle

Candidiasis
Candida albicans
Innate Immunity
Pattern Recognition Receptors
Ubiquitin-Protein Ligases
38 Citations (Scopus)

Targeting chromatin regulators inhibits leukemogenic gene expression in NPM1 mutant leukemia

Kühn, M. W. M., Song, E., Feng, Z., Sinha, A., Chen, C. W., Deshpande, A. J., Cusan, M., Farnoud, N., Mupo, A., Grove, C., Koche, R., Bradner, J. E., De Stanchina, E., Vassiliou, G. S., Hoshii, T. & Armstrong, S. A., 2016, In : Cancer Discovery. 6, 10, p. 1166-1181

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Chromatin
Leukemia
Homeobox Genes
Gene Expression
5 Citations (Scopus)
Tea Tree Oil
Acne Vulgaris
Gels
Research Personnel
12 Citations (Scopus)

Temporal changes in BEXSERO® antigen sequence type associated with genetic lineages of Neisseria meningitidis over a 15-year period in Western Australia

Mowlaboccus, S., Perkins, T., Smith, H., Sloots, T., Tozer, S., Prempeh, L., Tay, A. C. Y., Peters, F., Speers, D., Keil, A. D. & Kahler, C., 29 Jun 2016, In : PLoS One. 11, 6

Research output: Contribution to journalArticle

Open Access
Neisseria meningitidis
Western Australia
antigens
Antigens
vaccines
5 Citations (Scopus)

Temporal flux in ß-lactam resistance among Klebsiella pneumoniae in Western Australia

Hall, J. M., Ingram, P. R., O’Reilly, L. C. & Inglis, T. J. J., 2016, In : Journal of Medical Microbiology. 65, 5, p. 429-437 9 p.

Research output: Contribution to journalArticle

Lactams
Western Australia
Klebsiella pneumoniae
Ceftazidime
Aztreonam
15 Citations (Scopus)

TGF-α and IL-6 plasma levels selectively identify CML patients who fail to achieve an early molecular response or progress in the first year of therapy

Nievergall, E., Reynolds, J., Kok, C. H. H., Watkins, D. B. B., Biondo, M., Busfield, S. J. J., Vairo, G., Fuller, K. A., Erber, W. N., Sadras, T., Grose, R., Yeung, D. T. T., Lopez, A. F. F., Hiwase, D. K. K., Hughes, T. P. P. & White, D. L. L., 2016, In : Leukemia. 30, 6, p. 1263-1272 10 p.

Research output: Contribution to journalArticle

Interleukin-6
Leukemia, Myeloid, Chronic Phase
Cytokines
Therapeutics
Blast Crisis
1 Citation (Scopus)

TGFα expression in myeloid malignancies

Kavanagh, S., Mirzai, B., Fuller, K. & Erber, W., 2016, In : Journal of Clinical Pathology. 69, 6, p. 543-546

Research output: Contribution to journalArticle

Open Access
Transforming Growth Factors
Neoplasms
Acute Myeloid Leukemia
Blast Crisis
Leukemia, Myeloid, Accelerated Phase

The association between broad antigen HLA mismatches, eplet HLA mismatches and acute rejection after kidney transplantation

Do Nguyen, H., Wong, G., Chapman, J. R. R., McDonald, S. P. P., Coates, P. T. T., Watson, N., Russ, G. R. R., D'Orsogna, L. J. & Lim, W., 2016, In : Transplantation Direct. 2, 12, 8 p., e120.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)

The Australian laparoscopic non robotic radical prostatectomy experience – analysis of 2943 cases (USANZ supplement)

Louie-Johnsun, M. W., Handmer, M. M., Calopedos, R. J. S., Chabert, C., Cohen, R., Gianduzzo, T. R. J., Kearns, P. A., Moon, D. A., Ooi, J., Shannon, T., Sofield, D. & Tan, A. H. H., 2016, In : BJU International. 118, p. 43-48

Research output: Contribution to journalArticle

Robotics
Prostatectomy
Conversion to Open Surgery
Neoplasm Grading
Nuclear Family
17 Citations (Scopus)

The broad assessment of HCV genotypes 1 and 3 antigenic targets reveals limited cross-reactivity with implications for vaccine design

Von Delft, A., Humphreys, I. S., Brown, A., Pfafferott, K., Lucas, M., Klenerman, P., Lauer, G. M., Cox, A. L., Gaudieri, S. & Barnes, E., 2016, In : Gut. 65, 1, p. 112-123

Research output: Contribution to journalArticle

Open Access
Vaccines
Genotype
T-Lymphocytes
HLA Antigens
Infection
38 Citations (Scopus)

The contribution of tumour-derived exosomes to the hallmarks of cancer

Meehan, K. L. & Vella, L. J. J., 2016, In : Critical Reviews in Clinical Laboratory Sciences. 53, 2, p. 121-131 11 p.

Research output: Contribution to journalArticle

Exosomes
Tumors
Neoplasms
Cell death
Tumor Escape
2 Citations (Scopus)

The implications of endemic IMP-4 carbapenemase for clinical laboratory susceptibility testing

Goire, N., Harnett, G. B., O'Reilly, L. C., Ingram, P., Leung, M., Speers, D., Healy, P. E. & Inglis, T., 2016, In : Journal of Microbiological Methods. 124, p. 10-12

Research output: Contribution to journalArticle

meropenem
Microbial Sensitivity Tests
Enterobacteriaceae
Polymerase Chain Reaction
beta-lactamase IMP-4
6 Citations (Scopus)
Open Access
Spirurida
Physalopteridae
Abbreviata
Reptiles
Life Cycle Stages
17 Citations (Scopus)

The log TSH-free T4 relationship in a community-based cohort is nonlinear and is influenced by age, smoking and thyroid peroxidase antibody status.

Brown, S. J., Bremner, A., Hadlow, N. C., Feddema, P., Leedman, P., O'Leary, P. & Walsh, J., Nov 2016, In : Clinical Endocrinology. 85, 5, p. 789-796

Research output: Contribution to journalArticle

Open Access
Iodide Peroxidase
Smoking
Sigmoid Colon
Antibodies
Linear Models
21 Citations (Scopus)

The rare and undiagnosed diseases diagnostic service - application of massively parallel sequencing in a state-wide clinical service

Baynam, G., Pachter, N., McKenzie, F., Townshend, S., Slee, J., Kiraly-Borri, C., Vasudevan, A., Hawkins, A., Broley, S., Schofield, L., Verhoef, H., Walker, C. E. E., Molster, C., Blackwell, J. M., Jamieson, S., Tang, D., Lassmann, T., Mina, K., Beilby, J., Davis, M. & 5 othersLaing, N., Murphy, L., Weeramanthri, T., Dawkins, H. & Goldblatt, J., 2016, In : Orphanet Journal of Rare Diseases. 11, 7 p., 77.

Research output: Contribution to journalArticle

Genetic Services
Diagnostic Services
High-Throughput Nucleotide Sequencing
Rare Diseases
Western Australia
6 Citations (Scopus)
Glomerular Filtration Rate
Type 2 Diabetes Mellitus
Mortality
Cause of Death
Observational Studies
16 Citations (Scopus)

The risk of re-identification versus the need to identify individuals in rare disease research

Hansson, M. G., Lochmüller, H., Riess, O., Schaefer, F., Orth, M., Rubinstein, Y., Molster, C., Dawkins, H., Taruscio, D., Posada, M. & Woods, S., Nov 2016, In : European Journal of Human Genetics. 24, 11, p. 1553-1558

Research output: Contribution to journalArticle

Open Access
Research Subjects
Rare Diseases
Privacy
Confidentiality
Administrative Personnel
2 Citations (Scopus)

The "umbrella sign": A useful clue in the diagnosis of melanocytic lesions in sun damaged skin

Wood, B. A. & Harvey, N., 2016, In : American Journal of Dermatopathology. 38, 7, p. 504-509

Research output: Contribution to journalArticle

Pigmented Nevus
Solar System
Melanoma
Skin
Sunscreening Agents
12 Citations (Scopus)

The use of biochemical markers of bone turnover in the clinical management of primary and secondary osteoporosis

Vasikaran, S. D. & Chubb, P., 2016, In : Endocrine. 52, 2, p. 222-225 4 p.

Research output: Contribution to journalArticle

Bone Remodeling
Osteoporosis
Biomarkers
Physiologic Monitoring
Pathology
7 Citations (Scopus)

The y6 receptor suppresses bone resorption and stimulates bone formation in mice via a suprachiasmatic nucleus relay

Khor, E. C., Yulyaningsih, E., Driessler, F., Kovaĉić, N., Wee, N. K. Y., Kulkarni, R. N., Lee, N. J., Enriquez, R. F., Xu, J., Zhang, L., Herzog, H. & Baldock, P. A., Mar 2016, In : Bone. 84, p. 139-147 9 p.

Research output: Contribution to journalArticle

Suprachiasmatic Nucleus
Bone Resorption
Osteogenesis
Bone and Bones
Bone Remodeling

Tigecycline use in the outpatient parenteral antibiotic therapy setting

Ingram, P., Rawlins, M. D. M., Murray, R., Roberts, J. A. & Manning, L., Oct 2016, In : European Journal of Clinical Microbiology and Infectious Diseases. 35, 10, p. 1673-1677 5 p.

Research output: Contribution to journalArticle

Outpatients
Anti-Bacterial Agents
Nausea
Therapeutics
Infection
6 Citations (Scopus)

TNF Block Gene Variants Associate with Pain Intensity in Black Southern Africans with HIV-associated Sensory Neuropathy

Hendry, L. M., Wadley, A. L., Cherry, C. L., Price, P., Lombard, Z. & Kamerman, P. R., 2016, In : Clinical Journal of Pain. 32, 1, p. 45-50

Research output: Contribution to journalArticle

Tumor Necrosis Factor-alpha
HIV
Pain
Genes
Single Nucleotide Polymorphism
11 Citations (Scopus)

Towards a Better Understanding of the Life Cycle of Trypanosoma copemani

Botero, A., Clode, P., Peacock, C. & Thompson, R. C. A., 2016, In : Protist. 167, 1, p. 82-92

Research output: Contribution to journalArticle

Open Access
Trypanosoma
Life Cycle Stages
Potoroidae
Infection
Marsupialia
5 Citations (Scopus)

Treadmill running exercise prevents senile osteoporosis and upregulates the Wnt signaling pathway in SAMP6 mice

Chen, X., Li, L., Guo, J., Zhang, L., Yuan, Y., Chen, B., Sun, Z., Xu, J. & Zou, J., 2016, In : Oncotarget. 7, 44, p. 71072-71086 15 p.

Research output: Contribution to journalArticle

Wnt Signaling Pathway
Running
Osteoporosis
Up-Regulation
Bone and Bones
12 Citations (Scopus)

Treatment and outcomes in necrotising autoimmune myopathy: An Australian perspective

Ashton, C., Junckerstorff, R., Bundell, C., Hollingsworth, P. & Needham, M., 2016, In : Neuromuscular Disorders. 26, 11, p. 734-740

Research output: Contribution to journalArticle

Muscular Diseases
Signal Recognition Particle
Hydroxymethylglutaryl CoA Reductases
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Immunotherapy
25 Citations (Scopus)

Trends in seasonal influenza vaccine uptake during pregnancy in Western Australia: Implications for midwives

Regan, A., Mak, D. B., Hauck, Y. L., Gibbs, R., Tracey, L. & Effler, P., 2016, In : Women and Birth. 29, 5, p. 423-429

Research output: Contribution to journalArticle

Western Australia
Influenza Vaccines
Midwifery
Vaccination
Human Influenza
31 Citations (Scopus)

Unique and shared signalling pathways cooperate to regulate the differentiation of human CD4+ T cells into distinct effector subsets

Ma, C. S., Wong, N., Rao, G., Nguyen, A., Avery, D. T., Payne, K., Torpy, J., O'Young, P., Deenick, E., Bustamante, J., Puel, A., Okada, S., Kobayashi, M., Martinez-Barricarte, R., Elliott, M., Kilic, S. S., Baghdadi, J. E., Minegishi, Y., Bousfiha, A., Robertson, N. & 26 othersHambleton, S., Arkwright, P. D., French, M., Blincoe, A. K., Hsu, P., Campbell, D. E., Stormon, M. O., Wong, M., Adelstein, S., Fulcher, D. A., Cook, M. C., Stepensky, P., Boztug, K., Beier, R., Ikincioğullari, A., Ziegler, J. B., Gray, P., Picard, C., Boisson-Dupuis, S., Phan, T. G., Grimbacher, B., Warnatz, K., Holland, S. M., Uzel, G., Casanova, J. L. & Tangye, S. G., 11 Jul 2016, In : Journal of Experimental Medicine. 213 , 8, p. 1589-1608 20 p.

Research output: Contribution to journalArticle

Open Access
T-Lymphocytes
Mutation
Th17 Cells
Th1 Cells
Helper-Inducer T-Lymphocytes
13 Citations (Scopus)

Verapamil is less effective than triamcinolone for prevention of keloid scar recurrence after excision in a randomized controlled trial

Danielsen, P., Rea, S., Wood, F., Fear, M., Viola, H., Hool, L., Gankande, U., Alghamdi, M., Stevenson, A., Manzur, M. & Wallace, H., 2016, In : Acta Dermato-Venereologica. 96, 6, p. 774-778

Research output: Contribution to journalArticle

Keloid
Triamcinolone
Verapamil
Cicatrix
Randomized Controlled Trials
5 Citations (Scopus)

Viral Etiology and the Impact of Codetection in Young Children Presenting With Influenza-Like Illness

Lim, F. J., Wake, Z. V. V., Levy, A., Tempone, S., Moore, H. C., Richmond, P. C., De Klerk, N. H., Conway, N. T., Kiel, A. D. D., Effler, P., Smith, D. W. & Blyth, C. C., 2016, In : Journal of the Pediatric Infectious Diseases Society. p. 1-7 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Virulence and evolution of West Nile Virus, Australia, 1960-2012

Prow, N. A., Edmonds, J. H., Williams, D. T., Setoh, Y. X., Bielefeldt-Ohmann, H., Suen, W. W., Hobson-Peters, J., Van Den Hurk, A. F., Pyke, A. T., Hall-Mendelin, S., Northill, J. A., Johansen, C., Warrilow, D., Wang, J., Kirkland, P. D., Doggett, S., Andrade, C. C., Brault, A. C., Khromykh, A. A. & Hall, R. A., Aug 2016, In : Emerging Infectious Diseases. 22, 8, p. 1353-1362

Research output: Contribution to journalArticle

Open Access
West Nile virus
Virulence
Disease Outbreaks
Equine Encephalomyelitis
Horse Diseases
2015
10 Citations (Scopus)

25-Hydroxyvitamin D C3-epimer is universally present in neonatal Western Australian samples but is unlikely to contribute to diagnostic misclassification.

Cooke, D., Cooke, B. J., Bell, D., Vasikaran, S. & Glendenning, P., 2015, In : Annals of Clinical Biochemistry. N/A, p. 1-6

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abacavir-reactive memory T cells are present in drug naïve individuals

Lucas, A. D., Lucas, M., Strhyn, A., Keane, N. M., Mckinnon, E. J., Pavlos, R. K., Moran, E. M., Meyer-Pannwitt, V., Gaudieri, S., D'Orsogna, L., Kalams, S. A., Ostrov, D. A., Buus, S., Peters, B., Mallal, S. A. & Phillips, E. J., 12 Feb 2015, In : PLoS One. 10, 2, p. 1-16 16 p.

Research output: Contribution to journalArticle

Open Access
T-cells
T-lymphocytes
T-Lymphocytes
Data storage equipment
drugs
17 Citations (Scopus)

Absence of germline mutations in BAP1 in sporadic cases of malignant mesothelioma

Sneddon, S., Leon, J., Dick, I., Cadby, G., Olsen, N., Brims, F., Allcock, R., Moses, E., Melton, P., De Klerk, N., Musk, A., Robinson, B. & Creaney, J., 25 May 2015, In : Gene. 563, 1, p. 103-105

Research output: Contribution to journalArticle

Open Access
Germ-Line Mutation
Mesothelioma
Exome
High-Throughput Nucleotide Sequencing
Neoplasms
16 Citations (Scopus)

Absence of MERS-CoV antibodies in feral camels in Australia: Implications for the pathogen's origin and spread

Crameri, G., Durr, P. A., Barr, J., Yu, M., Graham, K., Williams, O. J., Kayali, G., Smith, D., Peiris, M., Mackenzie, J. S. & Wang, L. F., 2015, In : One Health. 1, p. 76-82

Research output: Contribution to journalArticle

Open Access
Camelus
Antibodies
Coronavirus Infections
Population
Middle East
1 Citation (Scopus)

A comparison of paediatric and adult infectious diseases consultations in Australia and New Zealand

Blyth, C., Walls, T., Cheng, A. C., Murray, R. J., Fisher, D. A., Ingram, P. & Davis, J. S., 2015, In : European Journal of Clinical Microbiology and Infectious Diseases. 34, p. 1589-1592

Research output: Contribution to journalArticle

7 Citations (Scopus)

Activation of protease-activated receptors (PARs)-1 and -2 promotes alpha-smooth muscle actin expression and release of cytokines from human lung fibroblasts

Asokananthan, N., Lan, R. S., Graham, P. T., Bakker, T., Tokanovic, A. & Stewart, G., 2015, In : Physiological Reports. 3, 2, p. 1-14

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)
Melaleuca
Tea Tree Oil
Enterococcus faecalis
Salts
Phosphates
6 Citations (Scopus)

Adapting the mobile laboratory to the changing needs of the ebolavirus epidemic

Inglis, T., 2015, In : Journal of Medical Microbiology. 64, 6, p. 587-590

Research output: Contribution to journalArticle

Ebolavirus
Western Africa
Microbiology
Epidemiology
Emergencies
32 Citations (Scopus)

A delivery system specifically approaching bone resorption surfaces to facilitate therapeutic modulation of microRNAs in osteoclasts

Liu, J., Dang, L., Li, D., Liang, C., He, X., Wu, H., Qian, A., Yang, Z., Au, D. W. T., Chiang, M. W. L., Zhang, B. T., Han, Q., Yue, K. K. M., Zhang, H., Lv, C., Pan, X., Xu, J., Bian, Z., Shang, P., Tan, W. & 4 othersLiang, Z., Guo, B., Lu, A. & Zhang, G., 2015, In : Biomaterials. 52, 1, p. 148-160

Research output: Contribution to journalArticle

Osteoclasts
Bone Resorption
MicroRNAs
Bone
Modulation
8 Citations (Scopus)

A Direct Pre-screen for Marine Bacteria Producing Compounds Inhibiting Quorum Sensing Reveals Diverse Planktonic Bacteria that are Bioactive

Linthorne, J., Chang, B., Flematti, G., Ghisalberti, E. & Sutton, D., Feb 2015, In : Marine Biotechnology. 17, 1, p. 33-42

Research output: Contribution to journalArticle

Quorum Sensing
quorum sensing
Vibrio harveyi
Chromobacterium violaceum
Pseudoalteromonas
3 Citations (Scopus)

Adverse events following influenza immunization reported by healthcare personnel using active surveillance based on text messages

Tracey, L. E., Regan, A. K., Mak, D. B. & Effler, P., 2015, In : Infection Control & Hospital Epidemiology. 36, 5, p. 608-610

Research output: Contribution to journalArticle

3 Citations (Scopus)

A flatworm from the genus waminoa (Acoela: Convolutidae) associated with bleached corals in Western Australia

Cooper, C., Clode, P., Thomson, D. P. & Stat, M., 2015, In : ZOOLOGICAL SCIENCE. 32, 5, p. 465-473

Research output: Contribution to journalArticle

Platyhelminthes
Western Australia
corals
molecular systematics
DNA primers
19 Citations (Scopus)

A Germline MTOR Mutation in Aboriginal Australian Siblings with Intellectual Disability, Dysmorphism, Macrocephaly, and Small Thoraces

Baynam, G., Overkov, A., Davis, M., Mina, K., Schofield, L., Allcock, R., Laing, N., Cook, M., Dawkins, H. & Goldblatt, J., 2015, In : American Journal of Medical Genetics, Part A. 167, 7, p. 1659-1667

Research output: Contribution to journalArticle

Megalencephaly
Germ-Line Mutation
Intellectual Disability
Costello Syndrome
Thorax
2 Citations (Scopus)
373 Downloads (Pure)
Open Access
File
Complement 3d Receptors
E-Box Elements
Chromatin
B-Lymphocytes
Upstream Stimulatory Factors
7 Citations (Scopus)

Anatomy and history of an external quality assessment program for interpretative comments in clinical biochemistry

Vasikaran, S., 2015, In : Clinical Biochemistry. 48, 7-8, p. 467-471

Research output: Contribution to journalArticle

Biochemistry
Anatomy
Educational Measurement
Australasia
Diagnostic Services
4 Citations (Scopus)

Andrographolide inhibits ovariectomy-induced bone loss via the suppression of RANKL signaling pathways

Wang, T., Liu, Q., Zhou, L., Yuan, J., Lin, X., Zeng, R., Liang, X., Zhao, J. & Xu, J., 17 Nov 2015, In : International Journal of Molecular Sciences. 16, 11, p. 27470-27481 12 p.

Research output: Contribution to journalArticle

Open Access
osteoporosis
Ovariectomy
bones
mice
Bone
27 Citations (Scopus)

Angiography reveals novel features of the retinal vasculature in healthy and diabetic mice

Mclenachan, S., Magno, A., Ramos, D., Catita, J., Mcmenamin, P. G., Chen, F., Rakoczy, E. & Ruberte, J., 2015, In : Experimental Eye Research. 138, p. 6-21

Research output: Contribution to journalArticle

Blood Vessels
Angiography
Ophthalmoscopy
Fluorescein Angiography
Optical Coherence Tomography
28 Citations (Scopus)

An NK cell population lacking FcRγ is expanded in chronically infected HIV patient

Zhou, J., Amran, F., Kramski, M., Angelovich, T. A., Elliott, J., Hearps, A. C., Price, P. & Jaworowski, A., 2015, In : Journal of Immunology. 194, 10, p. 4688-4697

Research output: Contribution to journalArticle

Natural Killer Cells
HIV
Population
Immunologic Monitoring
Therapeutics
23 Citations (Scopus)

A novel insect-specific flavivirus replicates only in Aedes-derived cells and persists at high prevalence in wild Aedes vigilax populations in Sydney, Australia

Mclean, B. J., Hobson-Peters, J., Webb, C. E., Watterson, D., Prow, N. A., Nguyen, H. D., Hall-Mendelin, S., Warrilow, D., Johansen, C., Jansen, C. C., Van Den Hurk, A. F., Beebe, N. W., Schnettler, E., Barnard, R. T. & Hall, R. A., Dec 2015, In : Virology. 486, p. 272-283 12 p.

Research output: Contribution to journalArticle

Open Access
Flavivirus
Aedes
Insects
Viruses
Culicidae