Centre for Respiratory Health

2023

Association of Computed Tomography Measures of Muscle and Adipose Tissue and Progressive Changes throughout Treatment with Clinical Endpoints in Patients with Advanced Lung Cancer Treated with Immune Checkpoint Inhibitors

Khan, A., Welman, C. J., Abed, A., O'Hanlon, S., Redfern, A., Azim, S., Lopez, P., Singh, F. & Khattak, A., Mar 2023, In: Cancers. 15, 5, 14 p., 1382.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Citation (Scopus)

Associations of physical activity and quality of life in parapneumonic effusion patients

Lopez, P., Fitzgerald, D. B., McVeigh, J. A., Badiei, A., Muruganandan, S., Newton, R. U., Straker, L., Lee, Y. C. G. & Peddle-McIntyre, C. J., Sept 2023, In: ERJ Open Research. 9, 5, 11 p., 00209-2023.

Research output: Contribution to journal › Article › peer-review

Open Access

Isolation and genome sequencing of cytomegaloviruses from Natal multimammate mice (Mastomys natalensis)

Hansen, F., Vučak, M., Nichols, J., Hughes, J., Bane, S., Camiolo, S., da Silva Filipe, A., Ostermann, E., Staliunaite, L., Chan, B., Mauch, T., Sogoba, N., Streblow, D. N., Voigt, S., Oestereich, L., Ehlers, B., Redwood, A. J., Feldmann, H., Brune, W., Rosenke, K., & 2 othersJarvis, M. A. & Davison, A. J., 29 Aug 2023, In: The Journal of general virology. 104, 8, 20 p., 001873.

Research output: Contribution to journal › Article › peer-review

Open Access

The relationship between clinical phenotype and kallikrein-kinin bioregulation in different forms of arthritis

Tan, D. B. A., Tedja, C., Kuster, L., Raymond, W. D., Harsanyi, A., Chowalloor, P. V., Misso, N. L., Argawal, S., Bhoola, K. D. & Keen, H. I., 18 May 2023, In: BMC Musculoskeletal Disorders. 24, 1, 396.

Research output: Contribution to journal › Article › peer-review

Open Access

Topical antibiotics prophylaxis for infections of indwelling pleural/peritoneal catheters (TAP-IPC): A pilot study

Lau, E. P. M., Faber, S., Charlesworth, C., Morey, S., Vekaria, S., Filion, P., Chakera, A. & Lee, Y. C. G., 2023, (Accepted/In press) In: Respirology.

Research output: Contribution to journal › Article › peer-review

Open Access

Using RNA-seq to identify suitable housekeeping genes for hypoxia studies in human adipose-derived stem cells

Ong, H. T., Prêle, C. M. & Dilley, R. J., Dec 2023, In: BMC Molecular and Cell Biology. 24, 1, 15 p., 16.

Research output: Contribution to journal › Article › peer-review

Open Access

Using x-ray micro computed tomography to quantify intracochlear fibrosis after cochlear implantation in a Guinea pig model

Braack, K., Miles, T., Amat, F., Brown, D., Atlas, M., Kuthubutheen, J., Mulders, W. & Prêle, C. M. A., Sept 2023, In: Heliyon. 9, 9, e19343.

Research output: Contribution to journal › Article › peer-review

Open Access

2022

Alteplase Dose Assessment for Pleural infection Therapy (ADAPT) Study-2: Use of 2.5 mg alteplase as a starting intrapleural dose

Popowicz, N., Ip, H., Lau, E. P. M., Piccolo, F., Dootson, K., Yeoh, C., Phu, W. Y., Brown, R., West, A., Ahmed, L. & Lee, Y. C. G., Jul 2022, In: Respirology. 27, 7, p. 510-516 7 p.

Research output: Contribution to journal › Article › peer-review

8 Citations (Web of Science)

An international survey on the use of intrapleural tissue plasminogen activator/DNase therapy for pleural infection

Lau, E. P. M., Eshraghi, M., Dootson, K., Yeoh, C., Phu, W. Y., Lee, Y. C. G. & Popowicz, N. D., Jan 2022, In: ERJ Open Research. 8, 1, 00590-2021.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Citations (Scopus)

Comprehensive genomic and tumour immune profiling reveals potential therapeutic targets in malignant pleural mesothelioma

Creaney, J., Patch, A. M., Addala, V., Sneddon, S. A., Nones, K., Dick, I. M., Lee, Y. C. G., Newell, F., Rouse, E. J., Naeini, M. M., Kondrashova, O., Lakis, V., Nakas, A., Waller, D., Sharkey, A., Mukhopadhyay, P., Kazakoff, S. H., Koufariotis, L. T., Davidson, A. L., Ramarao-Milne, P., & 10 othersHolmes, O., Xu, Q., Leonard, C., Wood, S., Grimmond, S. M., Bueno, R., Fennell, D. A., Pearson, J. V., Robinson, B. W. & Waddell, N., Dec 2022, In: Genome Medicine. 14, 1, 58.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Citations (Scopus)

Comprehensive Testing of Chemotherapy and Immune Checkpoint Blockade in Preclinical Cancer Models Identifies Additive Combinations

Principe, N., Aston, W. J., Hope, D. E., Tilsed, C. M., Fisher, S. A., Boon, L., Dick, I. M., Chin, W. L., McDonnell, A. M., Nowak, A. K., Lake, R. A., Chee, J. & Lesterhuis, W. J., 11 May 2022, In: Frontiers in Immunology. 13, 872295.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Citations (Scopus)

Diabetes induced by checkpoint inhibition in nonobese diabetic mice can be prevented or reversed by a JAK1/JAK2 inhibitor

Ge, T., Phung, A. L., Jhala, G., Trivedi, P., Principe, N., De George, D. J., Pappas, E. G., Litwak, S., Sanz-Villanueva, L., Catterall, T., Fynch, S., Boon, L., Kay, T. W., Chee, J., Krishnamurthy, B. & Thomas, H. E., 30 Oct 2022, In: Clinical and Translational Immunology. 11, 11, e1425.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Citations (Scopus)

Effects of photon radiation on DNA damage, cell proliferation, cell survival and apoptosis of murine and human mesothelioma cell lines

Keam, S., MacKinnon, K. M., Alonzo, R. A. D., Gill, S., Ebert, M. A., Nowak, A. K. & Cook, A. M., 1 Nov 2022, In: Advances in Radiation Oncology. 7, 6, 16 p., 101013.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Citation (Scopus)

Immune marker expression of irradiated mesothelioma cell lines

Chang, F., Keam, S., Hoang, T. S., Creaney, J., Gill, S., Nowak, A. K., Ebert, M. & Cook, A. M., 31 Oct 2022, In: Frontiers in Oncology. 12, 1020493.

Research output: Contribution to journal › Article › peer-review

Open Access

Plasma cell but not CD20-mediated B cell depletion protects from bleomycin-induced lung fibrosis

Prêle, C. M., Miles, T., Pearce, D. R., O'Donoghue, R. J., Grainge, C., Barrett, L., Birnie, K., Lucas, A. D., Baltic, S., Ernst, M., Rinaldi, C., Laurent, G. J., Knight, D. A., Fear, M., Hoyne, G., McAnulty, R. J. & Mutsaers, S. E., 1 Nov 2022, In: The European Respiratory Journal. 60, 5, 2101469.

Research output: Contribution to journal › Article › peer-review

Open Access

File

8 Citations (Scopus)

7 Downloads (Pure)

Profile of soluble factors in pleural effusions predict prognosis in mesothelioma

Dick, I. M., Lee, Y. C. G., Cheah, H. M., Miranda, A., Robinson, B. W. S. & Creaney, J., 2022, In: Cancer Biomarkers. 33, 1, p. 159-169 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Citations (Scopus)

2021

A cGAS-dependent response links DNA damage and senescence in alveolar epithelial cells: A potential drug target in IPF

Schuliga, M., Kanwal, A., Read, J., Blokland, K. E. C., Burgess, J. K., Prêle, C. M., Mutsaers, S. E., Grainge, C., Thomson, C., James, A., Bartlett, N. W. & Knight, D. A., Nov 2021, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 321, 5, p. L859-L871

Research output: Contribution to journal › Article › peer-review

Open Access

9 Citations (Scopus)

A senescence bystander effect in human lung fibroblasts

Waters, D. W., Schuliga, M., Pathinayake, P. S., Wei, L., Tan, H. Y., Blokland, K. E. C., Jaffar, J., Westall, G. P., Burgess, J. K., Prêle, C. M., Mutsaers, S. E., Grainge, C. L. & Knight, D. A., Sept 2021, In: Biomedicines. 9, 9, 1162.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Citations (Scopus)

Changes in expression of PD-L1 on peripheral T cells in patients with melanoma and lung cancer treated with PD-1 inhibitors

Dart, S. J., Cook, A. M., Millward, M. J., McDonnell, A. M., Chin, W. L., Hakeem, M. U., Meniawy, T. M. & Bowyer, S. E., Dec 2021, In: Scientific Reports. 11, 1, 15312.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Citations (Scopus)

Diagnosis and management of connective tissue disease-associated interstitial lung disease in Australia and New Zealand: A position statement from the Thoracic Society of Australia and New Zealand*

Jee, A. S., Sheehy, R., Hopkins, P., Corte, T. J., Grainge, C., Troy, L. K., Symons, K., Spencer, L. M., Reynolds, P. N., Chapman, S., de Boer, S., Reddy, T., Holland, A. E., Chambers, D. C., Glaspole, I. N., Jo, H. E., Bleasel, J. F., Wrobel, J. P., Dowman, L., Parker, M. J. S., & 4 othersWilsher, M. L., Goh, N. S. L., Moodley, Y. & Keir, G. J., Jan 2021, In: Respirology. 26, 1, p. 23-51 29 p.

Research output: Contribution to journal › Article › peer-review

Open Access

37 Citations (Scopus)

Protein tyrosine phosphatase 1B is involved in efficient type I interferon secretion upon viral infection

Reimer, E., Stempel, M., Chan, B., Bley, H. & Brinkmann, M. M., Mar 2021, In: Journal of Cell Science. 134, 5, jcs246421.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Citation (Scopus)

Reduced socs1 expression in lung fibroblasts from patients with ipf is not mediated by promoter methylation or mir155

Prêle, C. M., Iosifidis, T., McAnulty, R. J., Pearce, D. R., Badrian, B., Miles, T., Jamieson, S. E., Ernst, M., Thompson, P. J., Laurent, G. J., Knight, D. A. & Mutsaers, S. E., 2021, In: Biomedicines. 9, 5, 498.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Citation (Scopus)

The m15 locus of murine cytomegalovirus modulates natural killer cell responses to promote dissemination to the salivary glands and viral shedding

Chan, B., Arapović, M., Masters, L. L., Rwandamuiye, F., Jonjić, S., Smith, L. M. & Redwood, A. J., Jul 2021, In: Pathogens. 10, 7, 866.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Citation (Scopus)

Tumour draining lymph node-generated CD8 T cells play a role in controlling lung metastases after a primary tumour is removed but not when adjuvant immunotherapy is used

Fear, V., Forbes, C., Neeve, S., Fisher, S., Chee, J., Waithman, J., Ma, S., Lake, R., Nowak, A., Creaney, J., Brown, M., Saunders, C. & Robinson, B., Nov 2021, In: Cancer immunology, immunotherapy. 70, 11, p. 3249-3258 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Citations (Scopus)

Variation in treatment preferences of pulmonary exacerbations among Australian and New Zealand cystic fibrosis physicians

Currie, G., Tai, A., Snelling, T. & Schultz, A., 15 Jul 2021, In: BMJ Open Respiratory Research. 8, 1, e000956.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Citations (Scopus)

2020

Maintaining quality of life in patients with chronic obstructive pulmonary disease (COPD) by extending the maintenance phase of community-based pulmonary rehabilitation: protocol for a randomised controlled trial (ComEx3 Study)

Lopez, D., Cecins, N., Cockram, J., Collins, A., Landers, H., Sanfilippo, F., Briffa, T., Brims, F., Geelhoed, E., Murray, K., Phillips, K., Preen, D. & Jenkins, S., 24 Mar 2020, In: BMJ Open Respiratory Research. 7, 1, e000548.

Research output: Contribution to journal › Article › peer-review

Open Access

File

1 Citation (Scopus)

41 Downloads (Pure)

Repair of an Attenuated Low-Passage Murine Cytomegalovirus Bacterial Artificial Chromosome Identifies a Novel Spliced Gene Essential for Salivary Gland Tropism

Redwood, A. J., Masters, L. L., Chan, B., Leary, S., Forbes, C., Jonjić, S., Juranić Lisnić, V., Lisnić, B. & Smith, L. M., Nov 2020, In: Journal of Virology. 94, 22, e01456-20.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Citations (Scopus)

2019

Advances in pathological diagnosis of mesothelioma: what pulmonologists should know

Louw, A., Badiei, A., Creaney, J., Chai, M. S. & Lee, Y. C. G., 1 Jul 2019, In: Current Opinion in Pulmonary Medicine. 25, 4, p. 354-361 8 p.

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Bacteriology and clinical outcomes of patients with culture-positive pleural infection in Western Australia: A 6-year analysis

Brims, F., Popowicz, N., Rosenstengel, A., Hart, J., Yogendran, A., Read, C. A., Lee, F., Shrestha, R., Franke, A., Lewis, J. R., Kay, I., Waterer, G. & Lee, Y. C. G., Feb 2019, In: Respirology. 24, 2, p. 171-178 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

26 Citations (Scopus)

Body composition and nutritional status in malignant pleural mesothelioma: implications for activity levels and quality of life

Jeffery, E., Lee, Y. C. G., Newton, R. U., Lyons-Wall, P., McVeigh, J., Nowak, A. K., Cheah, H. M., Nguyen, B., Fitzgerald, D. B., Creaney, J., Straker, L. & Peddle-McIntyre, C. J., 1 Oct 2019, In: European Journal of Clinical Nutrition. 73, 10, p. 1412-1421 10 p.

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Inhibition of collagen production delays malignant mesothelioma tumor growth in a murine model

Abayasiriwardana, K. S., Wood, M. K., Prêle, C. M., Birnie, K. A., Robinson, B. W., Laurent, G. J., McAnulty, R. J. & Mutsaers, S. E., 5 Mar 2019, In: Biochemical and Biophysical Research Communications. 510, 2, p. 198-204 7 p.

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

MicroRNA Signatures in Malignant Pleural Mesothelioma Effusions

Birnie, K. A., Prele, C. M., Musk, A. W., de Klerk, N., Lee, Y. C. G., Fitzgerald, D., Allcock, R. J. N., Thompson, P. J., Creaney, J., Badrian, B. & Mutsaers, S. E., 31 Jul 2019, In: Disease Markers. 2019, 9 p., 8628612.

Research output: Contribution to journal › Article › peer-review

Open Access

17 Citations (Scopus)

Neo-antigen specific T cell responses indicate the presence of metastases before imaging

Fear, V. S., Forbes, C. A., Chee, J., Ma, S., Neeve, S., Celliers, L., Fisher, S. A., Dick, I., Creaney, J. & Robinson, B. W. S., 1 Dec 2019, In: Scientific Reports. 9, 1, 1 p., 14640.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Citations (Scopus)

Resequencing study confirms host defense and cell senescence gene variants contribute to the risk of idiopathic pulmonary fibrosis

Global IPF Consortium, 15 Jul 2019, In: American Journal of Respiratory and Critical Care Medicine. 200, 2, p. 199-208 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

71 Citations (Scopus)

2018

Airway Interleukin-33 and type 2 cytokines in adult patients with acute asthma

Poulsen, N. N., Bjerregaard, A., Khoo, S. K., Laing, I. A., Le Souëf, P., Backer, V., Rapley, L., Cohen, S. E., Barrett, L., Thompson, P., Baltic, S. & Porsbjerg, C., 1 Jul 2018, In: Respiratory Medicine. 140, p. 50-56 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Citations (Web of Science)

Genetic characterisation of molecular targets in carcinoma of unknown primary

Clynick, B., Dessauvagie, B., Sterrett, G., Harvey, N. T., Allcock, R. J. N., Saunders, C., Erber, W. & Meehan, K., 4 Jul 2018, In: Journal of Translational Medicine. 16, 1, 185.

Research output: Contribution to journal › Article › peer-review

Open Access

20 Citations (Web of Science)

Management of malignant pleural effusions: An official ATS/STS/STR clinical practice guideline

American Thoracic Society, Society of Thoracic Surgeons, and Society of Thoracic Radiology, 1 Oct 2018, In: American Journal of Respiratory and Critical Care Medicine. 198, 7, p. 839-849 11 p.

Research output: Contribution to journal › Article › peer-review

253 Citations (Scopus)

Out-of-pocket expenses experienced by rural Western Australians diagnosed with cancer

Newton, J. C., Johnson, C. E., Hohnen, H., Bulsara, M., Ives, A., McKiernan, S., Platt, V., McConigley, R., Slavova-Azmanova, N. S. & Saunders, C., 1 Oct 2018, In: Supportive Care in Cancer. 26, 10, p. 3543-3552 10 p.

Research output: Contribution to journal › Article › peer-review

37 Citations (Scopus)

Streptococcus pneumoniae potently induces cell death in mesothelial cells

Rashwan, R., Varano della Vergiliana, J. F., Lansley, S. M., Cheah, H. M., Popowicz, N., Paton, J. C., Waterer, G. W., Townsend, T., Kay, I., Brown, J. S. & Gary Lee, Y. C., 1 Jul 2018, In: PLoS One. 13, 7, e0201530.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Citations (Scopus)

2017

A massive pleural-based desmoid tumour

Mahmud, T., Mal, G., Majeed, F. A., Chai, S. M. & Lee, Y. C. G., 1 Jan 2017, In: Respirology Case Reports. 5, 1, 3 p., e00205.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Citations (Scopus)

BARD1 serum autoantibodies for the detection of lung cancer

Pilyugin, M., Descloux, P., André, P. A., Laszlo, V., Dome, B., Hegedus, B., Sardy, S., Janes, S., Bianco, A., Laurent, G. J. & Irminger-Finger, I., 7 Aug 2017, In: PLoS One. 12, 8, e0182356.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Citations (Scopus)

Characteristics associated with clinical severity and inflammatory phenotype of naturally occurring virus-induced exacerbations of asthma in adults

Bjerregaard, A., Laing, I. A., Poulsen, N., Backer, V., Sverrild, A., Fally, M., Khoo, S. K., Barrett, L., Baltic, S., Thompson, P. J., Chidlow, G., Sikazwe, C., Smith, D. W., Bochkov, Y. A., Le Souëf, P. & Porsbjerg, C., 1 Feb 2017, In: Respiratory Medicine. 123, p. 34-41 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Citations (Scopus)

CMV drives the expansion of highly functional memory T cells expressing NK-cell receptors in renal transplant recipients

Makwana, N., Foley, B., Fernandez, S., Lee, S., Irish, A., Pircher, H. & Price, P., 1 Aug 2017, In: European Journal of Immunology. 47, 8, p. 1324-1334 11 p.

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Comparison of outcomes following a cytological or histological diagnosis of malignant mesothelioma

Muruganandan, S., Alfonso, H., Franklin, P., Shilkin, K., Segal, A., Olsen, N., Reid, A., De Klerk, N., Musk, A. W. & Brims, F., 14 Mar 2017, In: British Journal of Cancer. 116, 6, p. 703-708 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

25 Citations (Scopus)

Dermatophagoides pteronyssinus lytFM encoding an NlpC/P60 endopeptidase is also present in mite-associated bacteria that express LytFM variants

Tang, V. H., Stewart, G. A. & Chang, B. J., 1 Sept 2017, In: FEBS Open Bio. 7, 9, p. 1267-1280 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Citations (Scopus)

Dose de-escalation of intrapleural tissue plasminogen activator therapy for pleural infection the alteplase dose assessment for pleural infection therapy project

Popowicz, N., Bintcliffe, O., De Fonseka, D., Blyth, K. G., Smith, N. A., Piccolo, F., Martin, G., Wong, D., Edey, A., Maskell, N. & Lee, Y. C. G., 1 Jun 2017, In: Annals of the American Thoracic Society. 14, 6, p. 929-936 8 p.

Research output: Contribution to journal › Article › peer-review

67 Citations (Scopus)

Effect of an indwelling pleural catheter vs talc pleurodesis on hospitalization days in patients with malignant pleural effusion: The AMPLE randomized clinical trial

Thomas, R., Fysh, E. T. H., Smith, N. A., Lee, P., Kwan, B. C. H., Yap, E., Horwood, F. C., Piccolo, F., Lam, D. C. L., Garske, L. A., Shrestha, R., Kosky, C., Read, C. A., Murray, K. & Lee, Y. C. G., 21 Nov 2017, In: JAMA: The Journal of the American Medical Association. 318, 19, p. 1903-1912 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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173 Citations (Scopus)

360 Downloads (Pure)

Gene-based analysis of regulatory variants identifies 4 putative novel asthma risk genes related to nucleotide synthesis and signaling

Ferreira, M. A. R., Jansen, R., Willemsen, G., Penninx, B. W., Bain, L. M., Vicente, C. T., Revez, J. A., Matheson, M. C., Hui, J., Tung, J. Y., Baltic, S., Le Souëf, P., Montgomery, G. W., Martin, N. G., Robertson, C. F., James, A., Thompson, P. J., Boomsma, D. I., Hopper, J. L., Hinds, D. A., & 3 othersWerder, R. B., Phipps, S. & Australian Asthma Genetics Consortium Collaborators, 1 Apr 2017, In: Journal of Allergy and Clinical Immunology. 139, 4, p. 1148-1157 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

54 Citations (Scopus)

287 Downloads (Pure)

HER2 mRNA transcript quantitation in breast cancer

Meehan, K., Clynick, B., Mirzai, B., Maslen, P., Harvey, J. & Erber, W. N., 1 May 2017, In: Clinical and Translational Oncology. 19, 5, p. 606-615 10 p.

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Human pleural fluid is a potent growth medium for Streptococcus pneumoniae

Popowicz, N. D., Lansley, S. M., Cheah, H. M., Kay, I. D., Carson, C. F., Waterer, G. W., Paton, J. C., Brown, J. S. & Lee, Y. C. G., 1 Nov 2017, In: PLoS One. 12, 11, e0188833.

Research output: Contribution to journal › Article › peer-review

Open Access

17 Citations (Scopus)

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