Centre for Ophthalmology and Visual Science (affiliated with the Lions Eye Institute)

Finished

Profiling the choroidal genetics to determine its role in myopia and myopic macular degeneration

Lee, S. (Investigator 01), Mackey, D. (Investigator 02), Guggenheim, J. (Investigator 03), Gharahkhani, P. (Investigator 04), Read, S. (Investigator 05) & Alonso-Caneiro, D. (Investigator 06)

Australian Vision Research

1/01/24 → 31/12/24

Project: Research

Genetic and environmental influences on the development of myopia: addressing a rising global prevalence post-pandemic.

Mountford, J. (Chief Investigator), dos Santos Carvalho, L. (Investigator 01), Clark, A. (Investigator 02), Jusuf, P. (Investigator 03), Mackey, D. (Investigator 04), Bui, B. (Investigator 05) & Mountford, J. (Investigator 06)

Department of Health (Western Australia)

1/06/23 → 31/05/24

Project: Research

Dual Inhibition of SGLT1 and 2 with Sotagliflozin– a Novel Approach to Maximize Cardiorenal Protection in Type 1 Diabetes.

Herat, L. (Investigator 01), Matthews, V. (Investigator 02), Schlaich, M. (Investigator 03), Sebastian, O. (Investigator 04), Rakoczy, E. (Investigator 05) & Matthews, J. (Investigator 06)

Diabetes Research Foundation of WA

1/01/23 → 31/07/24

Project: Research

WA Near-miss Awards: Ideas Grants 2021

Balaratnasingam, C. (Investigator 01)

Department of Health (Western Australia)

1/07/22 → 30/06/23

Project: Research

Establishing zebrafish morpholino as a model to study early-onset myopia.

Mountford, J. (Investigator 01), dos Santos Carvalho, L. (Investigator 02), Jusuf, P. (Investigator 03) & Clark, A. (Investigator 04)

Ophthalmic Research Institute of Australia

1/02/22 → 31/12/22

Project: Research

Validating novel treatments for cone-mediated vision loss

dos Santos Carvalho, L. (Investigator 01)

Department of Health (Western Australia)

1/10/21 → 31/12/22

Project: Research

The longitudinal relationship between macrovascular disease and retinopathy in type 2 diabetes

Davis, T. (Investigator 01), Drinkwater, J. (Investigator 02), Davis, W. (Investigator 03) & Chen, F. (Investigator 04)

Perth Eye Foundation

2/08/21 → 2/08/23

Project: Research

Developing novel gene therapy approaches for Usher syndrome

dos Santos Carvalho, L. (Investigator 01), Chen, F. (Investigator 02) & Mellough, C. (Investigator 03)

Channel 7 Telethon Trust

1/03/21 → 28/02/22

Project: Research

Applying machine learning to efficiently analyse fundus autofluorescence images in preparation for gene therapy

Mackey, D. (Investigator 01), Alonso-Caneiro, D. (Investigator 02) & Charng, J. (Investigator 03)

Ophthalmic Research Institute of Australia

1/01/21 → 31/12/21

Project: Research

Investigating human vascular endothelial growth factor physiology

Mellough, C. (Investigator 01), Rakoczy, E. (Investigator 02) & Constable, I. (Investigator 03)

Ophthalmic Research Institute of Australia

1/01/21 → 31/12/21

Project: Research

Looking for disease-causing mutations in families with dominant RP pedigrees

Chen, F. (Investigator 01), Fletcher, S. (Investigator 02), Lamey, T. (Investigator 03) & Florenz, L. (Investigator 04)

Retina Australia

1/01/21 → 31/12/21

Project: Research

An Australian Imaging Service: Melding the Clinical and Academic using a Distributed Federation of Enhanced XNATs

Mehnert, A. (Investigator 01) & Taylor, D. (Investigator 02)

Australian Research Data Commons ARDC

18/05/20 → 17/05/22

Project: Research

Atropine Treatment of Myopia (ATOM) – an international multicentre project

Lee, S. (Chief Investigator), Mackey, D. (Investigator 02), Hammond, C. (Investigator 03), Azuara-Blanco, A. (Investigator 04) & Chia, A. (Investigator 05)

The University of Western Australia

1/01/20 → 31/12/22

Project: Research

Optimizing a pipeline for developing treatment for CRB1-related inherited retinal diseases

Chen, F. (Investigator 01)

Ophthalmic Research Institute of Australia

1/01/20 → 31/12/20

Project: Research

Combining OCT and THz for improved detection of changes in corneal hydration indicating disease

Fitzgerald, T. (Chief Investigator), Cense, B. (Investigator 02), Chen, F. (Investigator 03), Gibson, A. (Investigator 04) & Deninger, A. (Investigator 05)

The University of Western Australia

1/01/20 → 31/12/21

Project: Research

Accelerating the identification and treatment of splice-altering mutations underlying inherited retinal diseases

Chen, F. (Investigator 01), Fletcher, S. (Investigator 02), McLenachan, S. (Investigator 03) & Cunningham, P. (Investigator 04)

NHMRC National Health and Medical Research Council

1/01/20 → 31/12/24

Project: Research

2020 - Topcon OCT System with OCTA and Anterior Segment Options

Yu, D.-Y. (Investigator 01), Morgan, W. (Investigator 02), Mackey, D. (Investigator 03), Mian, A. (Investigator 04), Cringle, S. (Investigator 05), McAllister, I. (Investigator 06), Balaratnasingam, C. (Investigator 07), Chen, F. (Investigator 08), McLenachan, S. (Investigator 09), Yu, P. (Investigator 10), Mehnert, A. (Investigator 11), Jones, T. (Investigator 12), Davis, E. (Investigator 13) & Clark, A. (Investigator 14)

NHMRC National Health and Medical Research Council

1/01/20 → 31/12/20

Project: Research

Determining a novel role for sodium glucose co-transporter 2 indiabetic retinopathy

Matthews, V. (Investigator 01), Herat, L. (Investigator 02), Schlaich, M. (Investigator 03) & Rakoczy, E. (Investigator 04)

Diabetes Australia

1/01/20 → 30/06/21

Project: Research

Determining a novel role for sodium glucose co-transporter 2 in the pathogenesis of diabetic retinopathy.

Herat, L. (Investigator 01), Matthews, V. (Investigator 02), Schlaich, M. (Investigator 03) & Rakoczy, E. (Investigator 04)

Diabetes Research Foundation of WA

1/01/20 → 31/12/20

Project: Research

Bringing Long-Tail Microscopy and Characterisation Data into the Light

Mehnert, A. (Investigator 01)

Australian Research Data Commons ARDC

19/07/19 → 18/07/20

Project: Research

Project Grant - Optimising treatment strategies for improved cone rescue in visual disorders

dos Santos Carvalho, L. (Investigator 01)

Department of Health (Western Australia)

1/07/19 → 30/06/20

Project: Research

2018 - Haag-Streit Octopus 900 Perimeter

Mackey, D. (Investigator 01), Morgan, W. (Investigator 02), Chen, F. (Investigator 03), Balaratnasingam, C. (Investigator 04), Hunt, D. (Investigator 05) & De Roach, J. (Investigator 06)

NHMRC National Health and Medical Research Council

1/01/19 → 31/12/19

Project: Research

Antisense oligomer mediated modulation of CNOT2 for the treatment of retinitis pigmentosa 11

Chen, F. (Investigator 01) & Fletcher, S. (Investigator 02)

Ophthalmic Research Institute of Australia

1/01/19 → 31/12/19

Project: Research

2018 - MaxOne High Resolution Multi Electrode Array MEA

Lister, R. (Investigator 01), Fox, A. (Investigator 02), Smith, N. (Investigator 03), Swaminatha Iyer, I. (Investigator 04), Hool, L. (Investigator 05), Bakker, T. (Investigator 06), Hodgetts, S. (Investigator 07), Rodger, J. (Investigator 08), Hemmi, J. (Investigator 09), Fitzgerald, M. (Investigator 10), Ravenscroft, G. (Investigator 11), Forrest, A. (Investigator 12), Chen, F. (Investigator 13), Dilley, R. (Investigator 14) & Wallace, V. (Investigator 15)

NHMRC National Health and Medical Research Council

1/01/19 → 31/12/19

Project: Research

Understanding, Predicting, Preventing and Treating the highly heritable, common eye diseases Myopia and Glaucoma to reduce Blindness and Visual Impairment

Mackey, D. (Investigator 01)

NHMRC National Health and Medical Research Council

1/01/19 → 29/02/24

Project: Research

Dual AAV retinal gene therapy approach for Usher 1F treatment

dos Santos Carvalho, L. (Investigator 01), Mellough, C. (Investigator 02) & Chen, F. (Investigator 03)

Retina Australia

1/01/19 → 31/12/19

Project: Research

Orbital Pressure Alteration and Interactions with Intracranial and Intraocular Pressure

Morgan, W. (Investigator 01) & Cringle, S. (Investigator 02)

NHMRC National Health and Medical Research Council

1/01/19 → 31/12/23

Project: Research

Translating Genetic Determinants of Glaucoma into Better Diagnosis and Treatment

Craig, J. (Investigator 01), Mackey, D. (Investigator 02), MacGregor, S. (Investigator 03) & Hewitt, A. (Investigator 04)

NHMRC National Health and Medical Research Council

1/01/19 → 31/12/24

Project: Research

TPCHRF - Round 6 - Investigating the genetic and environmental factors involved in early onset myopia

dos Santos Carvalho, L. (Investigator 01), Mellough, C. (Investigator 02), Jusuf, P. (Investigator 03) & Mackey, D. (Investigator 04)

Department of Health (Western Australia)

1/07/18 → 31/12/21

Project: Research

NCRIS ANDS Project - The Characterisation Data Enhanced Virtual Laboratory (C-DEVL)

Mehnert, A. (Investigator 01)

NCRIS Australian National Data Service

12/04/18 → 31/03/20

Project: Research

Stargardt macular degeneration: finding new genetic mutations and preparing patients for clinical trials

Chen, F. (Investigator 01)

Macular Disease Foundation Australia

1/01/18 → 31/12/19

Project: Research

Comparative Genomics of the Bared-nosed Wombat, a mammalian with five-star energy rating to elucidate mechanisms of energy wasting syndrome

Yazar, S. (Investigator 01), Meynert, A. (Investigator 02), Hewitt, A. (Investigator 03) & Mackey, D. (Investigator 04)

The University of Western Australia

1/01/18 → 31/12/18

Project: Research

Utilising patient-specific retinal organoids in vitro to investigate the effects of an SNRNP200 mutation causing early onset retinitis pigmentosa

Mellough, C. (Investigator 01), McLenachan, S. (Investigator 02) & Chen, F. (Investigator 03)

Retina Australia

1/01/18 → 31/12/18

Project: Research

Establishing Risk of Vision Loss in Leber Hereditary Optic Neuropathy Families

Mackey, D. (Investigator 01) & Kearns, L. (Investigator 02)

Ophthalmic Research Institute of Australia

1/01/18 → 31/12/18

Project: Research

WA ATOM extension study: Atropine treatment of myopia

Clark, A. (Investigator 01)

Ophthalmic Research Institute of Australia

1/01/18 → 31/12/18

Project: Research

MRFF - Developing Personalised Treatment for Retinal Degeneration

Chen, F. (Investigator 01)

NHMRC National Health and Medical Research Council

1/01/18 → 31/12/21

Project: Research

Delivering Durable Reliable High Quality Image Data

Mehnert, A. (Investigator 01)

NCRIS Australian National Data Service

11/01/17 → 30/07/17

Project: Research

Young adult myopia: genetic and environmental associations

Mackey, D. (Investigator 01), Sanfilippo, P. (Investigator 02), Hammond, C. (Investigator 03), Yazar, S. (Investigator 04), Rose, K. (Investigator 05), Milne, E. (Investigator 06), Lucas, R. (Investigator 07) & Chen, F. (Investigator 08)

NHMRC National Health and Medical Research Council

1/01/17 → 31/12/21

Project: Research

Evaluating cone-specific neuroprotective approaches

dos Santos Carvalho, L. (Investigator 01), Paquet-Durand, F. (Investigator 02) & Trifunovic, D. (Investigator 03)

The University of Western Australia

1/01/17 → 31/08/18

Project: Research

Merit Award - Projects - Voltage-gated potassium channels in inherited retinal dystrophy: disease mechanisms and treatment strategies

dos Santos Carvalho, L. (Investigator 01)

Department of Health (Western Australia)

1/01/17 → 30/06/18

Project: Research

Stem Cell Therapy for Age Related Macular Degeneration

Chen, F. (Investigator 01)

Ophthalmic Research Institute of Australia

1/01/17 → 31/12/17

Project: Research

Developing a novel glaucoma surgery for clinical use and commercialisation

Yu, D.-Y. (Investigator 01), Cringle, S. (Investigator 02) & Morgan, W. (Investigator 03)

NHMRC National Health and Medical Research Council

1/01/17 → 31/12/19

Project: Research

Targeting at risk relatives of glaucoma patients for early diagnosis and treatment (TARRGET)

Mackey, D. (Chief Investigator), Craig, J. (Chief Investigator), Goldberg, I. (Chief Investigator), Landers, J. (Chief Investigator) & Hewitt, A. (Chief Investigator)

Department of Health (Western Australia)

1/12/16 → 30/11/19

Project: Research

Targeting at risk relatives of glaucoma patients for early diagnosis and treatment (TARRGET)

Mackey, D. (Chief Investigator), Craig, J. (Chief Investigator), Goldberg, I. (Chief Investigator), Landers, J. (Chief Investigator) & Hewitt, A. (Chief Investigator)

Glaucoma Australia

1/12/16 → 30/11/19

Project: Research