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  • 2024

    A lipidomic based metabolic age score captures cardiometabolic risk independent of chronological age

    Wang, T., Beyene, H. B., Yi, C., Cinel, M., Mellett, N. A., Olshansky, G., Meikle, T. G., Wu, J., Dakic, A., Watts, G. F., Hung, J., Hui, J., Beilby, J., Blangero, J., Kaddurah-Daouk, R., Salim, A., Moses, E. K., Shaw, J. E., Magliano, D. J., Huynh, K., & 2 othersGiles, C. & Meikle, P. J., Jul 2024, In: EBioMedicine. 105, 18 p., 105199.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Development and validation of a plasmalogen score as an independent modifiable marker of metabolic health: population based observational studies and a placebo-controlled cross-over study

    Beyene, H. B., Huynh, K., Wang, T., Paul, S., Cinel, M., Mellett, N. A., Olshansky, G., Meikle, T. G., Watts, G. F., Hung, J., Hui, J., Beilby, J., Blangero, J., Moses, E. K., Shaw, J. E., Magliano, D. J., Giles, C. & Meikle, P. J., Jul 2024, In: EBioMedicine. 105, 20 p., 105187.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications

    Sterenborg, R. B. T. M., Steinbrenner, I., Li, Y., Bujnis, M. N., Naito, T., Marouli, E., Galesloot, T. E., Babajide, O., Andreasen, L., Astrup, A., Åsvold, B. O., Bandinelli, S., Beekman, M., Beilby, J. P., Bork-Jensen, J., Boutin, T., Brody, J. A., Brown, S. J., Brumpton, B., Campbell, P. J., & 121 othersCappola, A. R., Ceresini, G., Chaker, L., Chasman, D. I., Concas, M. P., Coutinho de Almeida, R., Cross, S. M., Cucca, F., Deary, I. J., Kjaergaard, A. D., Echouffo Tcheugui, J. B., Ellervik, C., Eriksson, J. G., Ferrucci, L., Freudenberg, J., Fuchsberger, C., Gieger, C., Giulianini, F., Gögele, M., Graham, S. E., Grarup, N., Gunjača, I., Hansen, T., Harding, B. N., Harris, S. E., Haunsø, S., Hayward, C., Hui, J., Ittermann, T., Jukema, J. W., Kajantie, E., Kanters, J. K., Kårhus, L. L., Kiemeney, L. A. L. M., Kloppenburg, M., Kühnel, B., Lahti, J., Langenberg, C., Lapauw, B., Leese, G., Li, S., Liewald, D. C. M., Linneberg, A., Lominchar, J. V. T., Luan, J., Martin, N. G., Matana, A., Meima, M. E., Meitinger, T., Meulenbelt, I., Mitchell, B. D., Møllehave, L. T., Mora, S., Naitza, S., Nauck, M., Netea-Maier, R. T., Noordam, R., Nursyifa, C., Okada, Y., Onano, S., Papadopoulou, A., Palmer, C. N. A., Pattaro, C., Pedersen, O., Peters, A., Pietzner, M., Polašek, O., Pramstaller, P. P., Psaty, B. M., Punda, A., Ray, D., Redmond, P., Richards, J. B., Ridker, P. M., Russ, T. C., Ryan, K. A., Olesen, M. S., Schultheiss, U. T., Selvin, E., Siddiqui, M. K., Sidore, C., Slagboom, P. E., Sørensen, T. I. A., Soto-Pedre, E., Spector, T. D., Spedicati, B., Srinivasan, S., Starr, J. M., Stott, D. J., Tanaka, T., Torlak, V., Trompet, S., Tuhkanen, J., Uitterlinden, A. G., van den Akker, E. B., van den Eynde, T., van der Klauw, M. M., van Heemst, D., Verroken, C., Visser, W. E., Vojinovic, D., Völzke, H., Waldenberger, M., Walsh, J. P., Wareham, N. J., Weiss, S., Willer, C. J., Wilson, S. G., Wolffenbuttel, B. H. R., Wouters, H. J. C. M., Wright, M. J., Yang, Q., Zemunik, T., Zhou, W., Zhu, G., Zöllner, S., Smit, J. W. A., Peeters, R. P., Köttgen, A., Teumer, A. & Medici, M., 30 Jan 2024, In: Nature Communications. 15, 1, 18 p., 888.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    3 Citations (Scopus)
  • 2023

    Genetic variants of TLR4, including the novel variant, rs5030719, and related genes are associated with susceptibility to clinical malaria in African children

    Ariff, A., Song, Y., Aguilar, R., Nhabomba, A., Manaca, M. N., Khoo, S. K., Wiertsema, S., Bassat, Q., Barbosa, A., Quintó, L., Laing, I. A., Guinovart, C., Alonso, P. L., Dobaño, C., Le Souëf, P. & Zhang, G., Dec 2023, In: Malaria Journal. 22, 1, 177.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Metabolic phenotyping of BMI to characterize cardiometabolic risk: evidence from large population-based cohorts

    Beyene, H. B., Giles, C., Huynh, K., Wang, T., Cinel, M., Mellett, N. A., Olshansky, G., Meikle, T. G., Watts, G. F., Hung, J., Hui, J., Cadby, G., Beilby, J., Blangero, J., Moses, E. K., Shaw, J. E., Magliano, D. J. & Meikle, P. J., Dec 2023, In: Nature Communications. 14, 1, 6280.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Citation (Scopus)
  • Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk

    China Kadoorie Biobank Collaborative Group, Qatar Genome Program Research (QGPR) Consortium, Shrine, N., Izquierdo, A. G., Chen, J., Packer, R., Hall, R. J., Guyatt, A. L., Batini, C., Thompson, R. J., Pavuluri, C., Malik, V., Hobbs, B. D., Moll, M., Kim, W., Tal-Singer, R., Bakke, P., Fawcett, K. A., John, C., Coley, K., & 130 othersPiga, N. N., Pozarickij, A., Lin, K., Millwood, I. Y., Chen, Z., Li, L., Wijnant, S. R. A., Lahousse, L., Brusselle, G., Uitterlinden, A. G., Manichaikul, A., Oelsner, E. C., Rich, S. S., Barr, R. G., Kerr, S. M., Vitart, V., Brown, M. R., Wielscher, M., Imboden, M., Jeong, A., Bartz, T. M., Gharib, S. A., Flexeder, C., Karrasch, S., Gieger, C., Peters, A., Stubbe, B., Hu, X., Ortega, V. E., Meyers, D. A., Bleecker, E. R., Gabriel, S. B., Gupta, N., Smith, A. V., Luan, J., Zhao, J. H., Hansen, A. F., Langhammer, A., Willer, C., Bhatta, L., Porteous, D., Smith, B. H., Campbell, A., Sofer, T., Lee, J., Daviglus, M. L., Yu, B., Lim, E., Xu, H., O'Connor, G. T., Thareja, G., Albagha, O. M. E., Suhre, K., Granell, R., Faquih, T. O., Hiemstra, P. S., Slats, A. M., Mullin, B. H., Hui, J., James, A., Beilby, J., Patasova, K., Hysi, P., Koskela, J. T., Wyss, A. B., Jin, J., Sikdar, S., Lee, M., May-Wilson, S., Pirastu, N., Kentistou, K. A., Joshi, P. K., Timmers, P. R. H. J., Williams, A. T., Free, R. C., Wang, X., Morrison, J. L., Gilliland, F. D., Chen, Z., Wang, C. A., Foong, R. E., Harris, S. E., Taylor, A., Redmond, P., Cook, J. P., Mahajan, A., Lind, L., Palviainen, T., Lehtimäki, T., Raitakari, O. T., Kaprio, J., Rantanen, T., Pietiläinen, K. H., Cox, S. R., Pennell, C. E., Hall, G. L., Gauderman, W. J., Brightling, C., Wilson, J. F., Vasankari, T., Laitinen, T., Salomaa, V., Mook-Kanamori, D. O., Timpson, N. J., Zeggini, E., Dupuis, J., Hayward, C., Brumpton, B., Langenberg, C., Weiss, S., Homuth, G., Schmidt, C. O., Probst-Hensch, N., Jarvelin, M. R., Morrison, A. C., Polasek, O., Rudan, I., Lee, J. H., Sayers, I., Rawlins, E. L., Dudbridge, F., Silverman, E. K., Strachan, D. P., Walters, R. G., Morris, A. P., London, S. J., Cho, M. H., Wain, L. V., Hall, I. P. & Tobin, M. D., Mar 2023, In: Nature Genetics. 55, 3, p. 410-422 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    30 Citations (Web of Science)
  • Plasma lipoprotein subclass variation in middle-aged and older adults: Sex-stratified distributions and associations with health status and cardiometabolic risk factors

    Masuda, R., Wist, J., Lodge, S., Kimhofer, T., Hunter, M., Hui, J., Beilby, J. P., Burnett, J. R., Dwivedi, G., Schlaich, M. P., Bong, S. H., Loo, R. L., Holmes, E., Nicholson, J. K. & Yeap, B. B., 1 Sept 2023, In: Journal of Clinical Lipidology. 17, 5, p. 677-687 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    2 Citations (Scopus)
  • Serum 21-deoxycortisol for diagnosis of non-classic congenital adrenal hyperplasia in women with androgen excess

    Ng, J. L., Lim, E. M., Zhang, R., Beilby, J. P., Watts, G. F., Brown, S. J. & Stuckey, B. G. A., 1 Dec 2023, In: The Journal of clinical endocrinology and metabolism. 108, 12, p. e1560-e1570

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Citation (Web of Science)
  • Open Access
    4 Citations (Scopus)
  • 2022

    Common genetic variants do not predict recurrent events in coronary heart disease patients

    Thompson, P. L., Hui, J., Beilby, J., Palmer, L. J., Watts, G. F., West, M. J., Kirby, A., Marschner, S., Simes, R. J., Sullivan, D. R., White, H. D., Stewart, R. & Tonkin, A. M., Dec 2022, In: BMC Cardiovascular Disorders. 22, 1, 96.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • 11 Citations (Scopus)
  • 2021

    Further heterogeneity in Silver–Russell syndrome: PLAG1 deletion in association with a complex chromosomal rearrangement

    Brereton, R. E., Nickerson, S. L., Woodward, K. J., Edwards, T., Sivamoorthy, S., Ramos Vasques Walters, F., Chabros, V., Marchin, V., Grumball, T., Kennedy, D., Uzaraga, J., Peverall, J., Arscott, G., Beilby, J., Choong, C. S., Townshend, S. & Azmanov, D. N., Oct 2021, In: American Journal of Medical Genetics Part A. 185, 10, p. 3136-3145 10 p.

    Research output: Contribution to journalArticlepeer-review

    6 Citations (Scopus)
  • 2020

    Interval breast cancer risk associations with breast density, family history and breast tissue aging

    Nguyen, T. L., Li, S., Dite, G. S., Aung, Y. K., Evans, C. F., Trinh, H. N., Baglietto, L., Stone, J., Song, Y. M., Sung, J., English, D. R., Jenkins, M. A., Dugué, P. A., Milne, R. L., Southey, M. C., Giles, G. G., Pike, M. C. & Hopper, J. L., 15 Jul 2020, In: International Journal of Cancer. 147, 2, p. 375-382 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    22 Citations (Scopus)
  • Machine learning-based dna methylation score for fetal exposure to maternal smoking: Development and validation in samples collected from adolescents and adults

    Rauschert, S., Melton, P. E., Heiskala, A., Karhunen, V., Burdge, G., Craig, J. M., Godfrey, K. M., Lillycrop, K., Mori, T. A., Beilin, L. J., Oddy, W. H., Pennell, C., Järvelin, M. R., Sebert, S. & Huang, R. C., Sept 2020, In: Environmental Health Perspectives. 128, 9, p. 1-11 11 p., 097003.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    21 Citations (Scopus)
  • 2019

    Analysis of the Epigenome in Multiplex Pre-eclampsia Families Identifies SORD, DGKI, and ICA1 as Novel Candidate Risk Genes

    Ariff, A., Melton, P. E., Brennecke, S. P. & Moses, E. K., 19 Mar 2019, In: Frontiers in Genetics. 10, MAR, 11 p., 227.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    8 Citations (Scopus)
  • Development and validation of a targeted gene sequencing panel for application to disparate cancers

    kConFab Investigators, 1 Dec 2019, In: Scientific Reports. 9, 1, 17052.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    15 Citations (Scopus)
  • Differential SLC6A4 methylation: a predictive epigenetic marker of adiposity from birth to adulthood

    EpiGen Consortium, 1 May 2019, In: International Journal of Obesity. 43, 5, p. 974-988 15 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    18 Citations (Scopus)
  • Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer

    EMBRACE Collaborators, GC-HBOC Study Collaborators, GEMO Study Collaborators, ABCTB Investigators, HEBON Investigators, BCFR Investigators & Stone, J., 1 Dec 2019, In: Nature Communications. 10, 1, 1741.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    78 Citations (Scopus)
  • Genome-wide association study of peripheral blood DNA methylation and conventional mammographic density measures

    Li, S., Dugué, P. A., Baglietto, L., Severi, G., Wong, E. M., Nguyen, T. L., Stone, J., English, D. R., Southey, M. C., Giles, G. G., Hopper, J. L. & Milne, R. L., 1 Oct 2019, In: International Journal of Cancer. 145, 7, p. 1768-1773 6 p.

    Research output: Contribution to journalArticlepeer-review

    12 Citations (Scopus)
  • Identification of novel sarcoma risk genes using a two-stage genome wide DNA sequencing strategy in cancer cluster families and population case and control cohorts

    International Sarcoma Kindred Study, 3 May 2019, In: BMC Medical Genetics. 20, 1, 10 p., 69.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    3 Citations (Scopus)
  • Inference about causation between body mass index and DNA methylation in blood from a twin family study

    Li, S., Wong, E. M., Bui, M., Nguyen, T. L., Joo, J. H. E., Stone, J., Dite, G. S., Dugué, P. A., Milne, R. L., Giles, G. G., Saffery, R., Southey, M. C. & Hopper, J. L., 1 Feb 2019, In: International Journal of Obesity. 43, 2, p. 243-252 10 p.

    Research output: Contribution to journalArticlepeer-review

    46 Citations (Scopus)
  • Measurement challenge: protocol for international case-control comparison of mammographic measures that predict breast cancer risk

    Dench, E., Bond-Smith, D., Darcey, E., Lee, G., Aung, Y. K., Chan, A., Cuzick, J., Ding, Z. Y., Evans, C. F., Harvey, J., Highnam, R., Hsieh, M. K., Kontos, D., Li, S., Mariapun, S., Nickson, C., Nguyen, T. L., Pertuz, S., Procopio, P., Rajaram, N., & 12 othersRepich, K., Tan, M., Teo, S. H., Trinh, N. H., Ursin, G., Wang, C., Dos-Santos-Silva, I., McCormack, V., Nielsen, M., Shepherd, J., Hopper, J. L. & Stone, J., 31 Dec 2019, In: BMJ Open. 9, 12, p. e031041 e031041.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    8 Citations (Scopus)
  • Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight

    Küpers, L. K., Monnereau, C., Sharp, G. C., Yousefi, P., Salas, L. A., Ghantous, A., Page, C. M., Reese, S. E., Wilcox, A. J., Czamara, D., Starling, A. P., Novoloaca, A., Lent, S., Roy, R., Hoyo, C., Breton, C. V., Allard, C., Just, A. C., Bakulski, K. M., Holloway, J. W., & 107 othersEverson, T. M., Xu, C. J., Huang, R. C., van der Plaat, D. A., Wielscher, M., Merid, S. K., Ullemar, V., Rezwan, F. I., Lahti, J., van Dongen, J., Langie, S. A. S., Richardson, T. G., Magnus, M. C., Nohr, E. A., Xu, Z., Duijts, L., Zhao, S., Zhang, W., Plusquin, M., DeMeo, D. L., Solomon, O., Heimovaara, J. H., Jima, D. D., Gao, L., Bustamante, M., Perron, P., Wright, R. O., Hertz-Picciotto, I., Zhang, H., Karagas, M. R., Gehring, U., Marsit, C. J., Beilin, L. J., Vonk, J. M., Jarvelin, M. R., Bergström, A., Örtqvist, A. K., Ewart, S., Villa, P. M., Moore, S. E., Willemsen, G., Standaert, A. R. L., Håberg, S. E., Sørensen, T. I. A., Taylor, J. A., Räikkönen, K., Yang, I. V., Kechris, K., Nawrot, T. S., Silver, M. J., Gong, Y. Y., Richiardi, L., Kogevinas, M., Litonjua, A. A., Eskenazi, B., Huen, K., Mbarek, H., Maguire, R. L., Dwyer, T., Vrijheid, M., Bouchard, L., Baccarelli, A. A., Croen, L. A., Karmaus, W., Anderson, D., de Vries, M., Sebert, S., Kere, J., Karlsson, R., Arshad, S. H., Hämäläinen, E., Routledge, M. N., Boomsma, D. I., Feinberg, A. P., Newschaffer, C. J., Govarts, E., Moisse, M., Fallin, M. D., Melén, E., Prentice, A. M., Kajantie, E., Almqvist, C., Oken, E., Dabelea, D., Boezen, H. M., Melton, P. E., Wright, R. J., Koppelman, G. H., Trevisi, L., Hivert, M. F., Sunyer, J., Munthe-Kaas, M. C., Murphy, S. K., Corpeleijn, E., Wiemels, J., Holland, N., Herceg, Z., Binder, E. B., Davey Smith, G., Jaddoe, V. W. V., Lie, R. T., Nystad, W., London, S. J., Lawlor, D. A., Relton, C. L., Snieder, H. & Felix, J. F., 1 Dec 2019, In: Nature Communications. 10, 1, 1893.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    126 Citations (Scopus)
  • Statins do not directly inhibit the activity of major epigenetic modifying enzymes

    Bridgeman, S., Northrop, W., Ellison, G., Sabapathy, T., Melton, P. E., Newsholme, P. & Mamotte, C. D. S., 10 Apr 2019, In: Cancers. 11, 4, 516.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    10 Citations (Scopus)
  • The association between mammographic density and breast cancer risk in Western Australian Aboriginal women

    Darcey, E., Lloyd, R., Cadby, G., Pilkington, L., Redfern, A., Thompson, S. C., Saunders, C., Wylie, E. & Stone, J., 15 Jul 2019, In: Breast Cancer Research and Treatment. 176, 1, p. 235-242 8 p.

    Research output: Contribution to journalArticlepeer-review

    4 Citations (Scopus)
  • 2018

    Airway function in infancy is linked to airflow measurements and respiratory symptoms from childhood into adulthood

    Owens, L., Laing, I. A., Zhang, G., Turner, S. & Le Souëf, P. N., 1 Aug 2018, In: Pediatric Pulmonology. 53, 8, p. 1082-1088 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    20 Citations (Scopus)
  • Causal effect of smoking on DNA methylation in peripheral blood: A twin and family study

    Li, S., Wong, E. M., Bui, M., Nguyen, T. L., Joo, J. H. E., Stone, J., Dite, G. S., Giles, G. G., Saffery, R., Southey, M. C. & Hopper, J. L., 9 Feb 2018, In: Clinical Epigenetics. 10, 1, 18.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    69 Citations (Scopus)
  • Cell-type-specific eQTL of primary melanocytes facilitates identification of melanoma susceptibility genes

    Zhang, T., Choi, J., Kovacs, M. A., Shi, J., Xu, M., NISC Comparative Sequencing, Melanoma Meta-Anal Consortium, Goldstein, A. M., Trower, A. J., Bishop, D. T., Iles, M. M., Duffy, D. L., MacGregor, S., Amundadottir, L. T., Law, M. H., Loftus, S. K., Pavan, W. J. & Brown, K. M., Nov 2018, In: Genome Research. 28, 11, p. 1621-1635 15 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    51 Citations (Scopus)
  • Clinical significance of circulating microRNAs as markers in detecting and predicting congenital heart defects in children

    Song, Y., Higgins, H., Guo, J., Harrison, K., Schultz, E. N., Hales, B. J., Moses, E. K., Goldblatt, J., Pachter, N. & Zhang, G., 27 Feb 2018, In: Journal of Translational Medicine. 16, 1, 42.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    31 Citations (Scopus)
  • Cord Blood IL-12 Confers Protection to Clinical Malaria in Early Childhood Life

    Song, Y., Aguilar, R., Guo, J., Manaca, M. N., Nhabomba, A., Berthoud, T. K., Khoo, S. K., Wiertsema, S., Barbosa, A., Quintó, L., Laing, I. A., Mayor, A., Guinovart, C., Alonso, P. L., Lesouëf, P. N., Dobaño, C. & Zhang, G. B., 1 Dec 2018, In: Scientific Reports. 8, 1, 10860.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Citation (Scopus)
  • Cuffed vs. uncuffed tracheal tubes in children: a randomised controlled trial comparing leak, tidal volume and complications

    Chambers, N. A., Ramgolam, A., Sommerfield, D., Zhang, G., Ledowski, T., Thurm, M., Lethbridge, M., Hegarty, M. K. & von Ungern-Sternberg, B. S., 1 Feb 2018, In: Anaesthesia. 73, 2, p. 160-168 9 p.

    Research output: Contribution to journalArticlepeer-review

    53 Citations (Scopus)
  • Epigenetics, heritability and longitudinal analysis

    Nustad, H. E., Almeida, M., Canty, A. J., LeBlanc, M., Page, C. M. & Melton, P. E., 17 Sept 2018, In: BMC Genetics. 19, Suppl 1, p. 77 77.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    5 Citations (Scopus)
  • Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation

    LifeLines Cohort Study, 1 Dec 2018, In: Nature Communications. 9, 1, 4455.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    179 Citations (Scopus)
  • Genome-wide average DNA methylation is determined in utero

    Li, S., Wong, E. M., Dugué, P. A., McRae, A. F., Kim, E., Joo, J. H. E., Nguyen, T. L., Stone, J., Dite, G. S., Armstrong, N. J., Mather, K. A., Thalamuthu, A., Wright, M. J., Ames, D., Milne, R. L., Craig, J. M., Saffery, R., Montgomery, G. W., Song, Y-M., Sung, J., & 5 othersSpector, T. D., Sachdev, P. S., Giles, G. G., Southey, M. C. & Hopper, J. L., 1 Jun 2018, In: International Journal of Epidemiology. 47, 3, p. 908-916 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    30 Citations (Scopus)
  • InforMD: A new initiative to raise public awareness about breast density

    Hugo, H. J., Zysk, A., Dasari, P., Britt, K., Hopper, J. L., Stone, J., Thompson, E. W. & Ingman, W. V., 6 Feb 2018, In: ecancermedicalscience. 12, 807.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    3 Citations (Scopus)
  • Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways

    Melanoma GWAS Consortium, 1 Dec 2018, In: Nature Communications. 9, 1, 4774.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    76 Citations (Scopus)
  • PCR screening of antimicrobial resistance genes in faecal samples from Australian and Chinese children

    Ravensdale, J. T., Xian, D. T. W., Wei, C. M., Lv, Q., Wen, X., Guo, J., Coorey, R., LeSouëf, P., Lu, F., Zhang, G. & Dykes, G. A., 1 Sept 2018, In: Journal of Global Antimicrobial Resistance. 14, p. 178-181 4 p.

    Research output: Contribution to journalArticlepeer-review

    2 Citations (Scopus)
  • Prevalence of allergic sensitization, hay fever, eczema, and asthma in a longitudinal birth cohort

    Owens, L., Laing, I. A., Zhang, G., Turner, S. & Le Souëf, P. N., 1 Jan 2018, In: Journal of Asthma and Allergy. 11, p. 173-180 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    23 Citations (Scopus)
  • Should breast cancer screening programs routinely measure mammographic density?

    Stone, J., Apr 2018, In: Journal of Medical Imaging and Radiation Oncology. 62, 2, p. 151-158 8 p.

    Research output: Contribution to journalArticlepeer-review

    6 Citations (Scopus)
  • Vitamin A protects the preterm lamb diaphragm against adverse effects of mechanical ventilation

    Song, Y., Dahl, M. J., Leavitt, W., Alvord, J., Bradford, C. Y., Albertine, K. H. & Pillow, J. J., 13 Aug 2018, In: Frontiers in Physiology. 9, AUG, 1119.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    3 Citations (Scopus)
  • 2017

    ANRIL Promoter DNA Methylation: A Perinatal Marker for Later Adiposity

    Lillycrop, K., Murray, R., Cheong, C., Teh, A. L., Clarke-Harris, R., Barton, S., Costello, P., Garratt, E., Cook, E., Titcombe, P., Shunmuganathan, B., Liew, S. J., Chua, Y-C., Lin, X., Wu, Y., Burdge, G. C., Cooper, C., Inskip, H. M., Karnani, N., Hopkins, J. C., & 14 othersChilds, C. E., Chavez, C. P., Calder, P. C., Yap, F., Lee, Y. S., Chong, Y. S., Melton, P., Beilin, L., Huang, R-C., Gluckman, P. D., Harvey, N., Hanson, M. A., Holbrook, J. D. & Godfrey, K. M., May 2017, In: EBioMedicine. 19, p. 60–72 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    62 Citations (Scopus)
  • Association analysis identifies 65 new breast cancer risk loci

    Michailidou, K., Lindström, S., Dennis, J., Beesley, J., Hui, S., Kar, S., Lemaçon, A., Soucy, P., Glubb, D., Rostamianfar, A., Bolla, M. K., Wang, Q., Tyrer, J., Dicks, E., Lee, A., Wang, Z., Allen, J., Keeman, R., Eilber, U., French, J. D., & 233 othersChen, X. Q., Fachal, L., McCue, K., Reed, A. E. M. C., Ghoussaini, M., Carroll, J. S., Jiang, X., Finucane, H., Adams, M., Adank, M. A., Ahsan, H., Aittomäki, K., Anton-Culver, H., Antonenkova, N. N., Arndt, V., Aronson, K. J., Arun, B., Auer, P. L., Bacot, F., Barrdahl, M., Baynes, C., Beckmann, M. W., Behrens, S., Benitez, J., Bermisheva, M., Bernstein, L., Blomqvist, C., Bogdanova, N. V., Bojesen, S. E., Bonanni, B., Børresen-Dale, A. L., Brand, J. S., Brauch, H., Brennan, P., Brenner, H., Brinton, L., Broberg, P., Brock, I. W., Broeks, A., Brooks-Wilson, A., Brucker, S. Y., Brüning, T., Burwinkel, B., Butterbach, K., Cai, Q., Cai, H., Caldés, T., Canzian, F., Carracedo, A., Carter, B. D., Castelao, J. E., Chan, T. L., Cheng, T. Y. D., Chia, K. S., Choi, J. Y., Christiansen, H., Clarke, C. L., Collée, M., Conroy, D. M., Cordina-Duverger, E., Cornelissen, S., Cox, D. G., Cox, A., Cross, S. S., Cunningham, J. M., Czene, K., Daly, M. B., Devilee, P., Doheny, K. F., Dörk, T., Dos-Santos-Silva, I., Dumont, M., Durcan, L., Dwek, M., Eccles, D. M., Ekici, A. B., Eliassen, A. H., Ellberg, C., Elvira, M., Engel, C., Eriksson, M., Fasching, P. A., Figueroa, J., Flesch-Janys, D., Fletcher, O., Flyger, H., Fritschi, L., Gaborieau, V., Gabrielson, M., Gago-Dominguez, M., Gao, Y. T., Gapstur, S. M., García-Sáenz, J. A., Gaudet, M. M., Georgoulias, V., Giles, G. G., Glendon, G., Goldberg, M. S., Goldgar, D. E., González-Neira, A., Alnæs, G. I. G., Grip, M., Gronwald, J., Grundy, A., Guénel, P., Haeberle, L., Hahnen, E., Haiman, C. A., Håkansson, N., Hamann, U., Hamel, N., Hankinson, S., Harrington, P., Hart, S. N., Hartikainen, J. M., Hartman, M., Hein, A., Heyworth, J., Hicks, B., Hillemanns, P., Ho, D. N., Hollestelle, A., Hooning, M. J., Hoover, R. N., Hopper, J. L., Hou, M. F., Hsiung, C. N., Huang, G., Humphreys, K., Ishiguro, J., Ito, H., Iwasaki, M., Iwata, H., Jakubowska, A., Janni, W., John, E. M., Johnson, N., Jones, K., Jones, M., Jukkola-Vuorinen, A., Kaaks, R., Kabisch, M., Kaczmarek, K., Kang, D., Kasuga, Y., Kerin, M. J., Khan, S., Khusnutdinova, E., Kiiski, J. I., Kim, S. W., Knight, J. A., Kosma, V. M., Kristensen, V. N., Krüger, U., Kwong, A., Lambrechts, D., Le Marchand, L., Lee, E., Lee, M. H., Lee, J. W., Lee, C. N., Lejbkowicz, F., Li, J., Lilyquist, J., Lindblom, A., Lissowska, J., Lo, W. Y., Loibl, S., Long, J., Lophatananon, A., Lubinski, J., Luccarini, C., Lux, M. P., Ma, E. S. K., MacInnis, R. J., Maishman, T., Makalic, E., Malone, K. E., Kostovska, I. M., Mannermaa, A., Manoukian, S., Manson, J. A. E., Margolin, S., Mariapun, S., Martinez, M. E., Matsuo, K., Mavroudis, D., McKay, J., McLean, C., Meijers-Heijboer, H., Meindl, A., Menéndez, P., Menon, U., Meyer, J., Miao, H., Miller, N., Taib, N. A. M., Muir, K., Mulligan, A. M., Mulot, C., Neuhausen, S. L., Nevanlinna, H., Neven, P., Nielsen, S. F., Noh, D. Y., Nordestgaard, B. G., Norman, A., Olopade, O. I., Olson, J. E., Olsson, H., Olswold, C., Orr, N., Pankratz, V. S., Park, S. K., Park-Simon, T. W., Lloyd, R., Perez, J. I. A., Peterlongo, P., Peto, J., Phillips, K. A., Pinchev, M., Plaseska-Karanfilska, D., Prentice, R., Presneau, N., Prokofyeva, D., Pugh, E., Pylkäs, K., Rack, B., Radice, P., Stone, J., NBCS Collaborators, ABCTB Investigators & kConFab/AOCS Investigators, 2 Nov 2017, In: Nature. 551, 7678, p. 92-94 3 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    897 Citations (Scopus)
  • Causes of blood methylomic variation for middle-aged women measured by the HumanMethylation450 array

    Li, S., Wong, E. M., Nguyen, T. L., Joo, J. H. E., Stone, J., Dite, G. S., Giles, G. G., Saffery, R., Southey, M. C. & Hopper, J. L., 2 Nov 2017, In: Epigenetics. 12, 11, p. 973-981 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    12 Citations (Scopus)
  • Environment changes genetic effects on respiratory conditions and allergic phenotypes

    Song, Y., Schwager, M. J., Backer, V., Guo, J., Porsbjerg, C., Khoo, S. K., Laing, I. A., Moses, E. K., LeSouëf, P. & Zhang, G., 24 Jul 2017, In: Scientific Reports. 7, 1, 6342.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    12 Citations (Scopus)
  • Exome array analysis suggests an increased variant burden in families with schizophrenia

    McCarthy, N. S., Melton, P. E., Ward, S. V., Allan, S. M., Dragovic, M., Clark, M., Morar, B., Rubio, J. P. P., Badcock, J. C., Morgan, V. A., Moses, E. K. & Jablensky, A., Jul 2017, In: Schizophrenia Research. 185, p. 9-16 8 p.

    Research output: Contribution to journalArticlepeer-review

    15 Citations (Scopus)
  • Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

    Justice, A. E., Winkler, T. W., Feitosa, M. F., Graff, M., Fisher, V. A., Young, K., Barata, L., Deng, X., Czajkowski, J., Hadley, D., Ngwa, J. S., Ahluwalia, T. S., Chu, A. Y., Heard-Costa, N. L., Lim, E., Perez, J., Eicher, J. D., Kutalik, Z., Xue, L., Mahajan, A., & 297 othersRenström, F., Wu, J., Qi, Q., Ahmad, S., Alfred, T., Amin, N., Bielak, L. F., Bonnefond, A., Bragg, J., Cadby, G., Chittani, M., Coggeshall, S., Corre, T., Direk, N., Eriksson, J., Fischer, K., Gorski, M., Harder, M. N., Horikoshi, M., Huang, T., Huffman, J. E., Jackson, A. U., Justesen, J. M., Kanoni, S., Kinnunen, L., Kleber, M. E., Komulainen, P., Kumari, M., Lim, U., Luan, J., Lyytikäinen, L. P., Mangino, M., Manichaikul, A., Marten, J., Middelberg, R. P. S., Müller-Nurasyid, M., Navarro, P., Pe'russe, L., Pervjakova, N., Sarti, C., Smith, A. V., Smith, J. A., Stanča'kova, A., Strawbridge, R. J., Stringham, H. M., Sung, Y. J., Tanaka, T., Teumer, A., Trompet, S., Van Der Laan, S. W., Van Der Most, P. J., Van Vliet-Ostaptchouk, J. V., Vedantam, S. L., Verweij, N., Vink, J. M., Vitart, V., Wu, Y., Yengo, L., Zhang, W., Zhao, J. H., Zimmermann, M. E., Zubair, N., Abecasis, G. R., Adair, L. S., Afaq, S., Afzal, U., Bakker, S. J. L., Bartz, T. M., Beilby, J., Bergman, R. N., Bergmann, S., Biffar, R., Blangero, J., Boerwinkle, E., Bonnycastle, L. L., Bottinger, E., Braga, D., Buckley, B. M., Buyske, S., Campbell, H., Chambers, J. C., Collins, F. S., Curran, J. E., De Borst, G. J., De Craen, A. J. M., De Geus, E. J. C., Dedoussis, G., Delgado, G. E., Den Ruijter, H. M., Eiriksdottir, G., Eriksson, A. L., Esko, T., Faul, J. D., Ford, I., Forrester, T., Gertow, K., Gigante, B., Glorioso, N., Gong, J., Grallert, H., Grammer, T. B., Grarup, N., Haitjema, S., Hallmans, G., Hamsten, A., Hansen, T., Harris, T. B., Hartman, C. A., Hassinen, M., Hastie, N. D., Heath, A. C., Hernandez, D., Hindorff, L., Hocking, L. J., Hollensted, M., Holmen, O. L., Homuth, G., Hottenga, J. J., Huang, J., Hung, J., Hutri-Kähönen, N., Ingelsson, E., James, A. L., Jansson, J. O., Jarvelin, M. R., Jhun, M. A., Jorgensen, M. E., Juonala, M., Kähönen, M., Karlsson, M., Koistinen, H. A., Kolcic, I., Kolovou, G., Kooperberg, C., Krämer, B. K., Kuusisto, J., Kvaloy, K., Lakka, T. A., Langenberg, C., Launer, L. J., Leander, K., Lee, N. R., Lind, L., Lindgren, C. M., Linneberg, A., Lobbens, S., Loh, M., Lorentzon, M., Luben, R., Lubke, G., Ludolph-Donislawski, A., Lupoli, S., Madden, P. A. F., Männikkö, R., Marques-Vidal, P., Martin, N. G., McKenzie, C. A., McKnight, B., Mellström, D., Menni, C., Montgomery, G. W., Musk, A. W., Narisu, N., Nauck, M., Nolte, I. M., Oldehinkel, A. J., Olden, M., Ong, K. K., Padmanabhan, S., Peyser, P. A., Pisinger, C., Porteous, D. J., Raitakari, O. T., Rankinen, T., Rao, D. C., Rasmussen-Torvik, L. J., Rawal, R., Rice, T., Ridker, P. M., Rose, L. M., Bien, S. A., Rudan, I., Sanna, S., Sarzynski, M. A., Sattar, N., Savonen, K., Schlessinger, D., Scholtens, S., Schurmann, C., Scott, R. A., Sennblad, B., Siemelink, M. A., Silbernagel, G., Slagboom, P. E., Snieder, H., Staessen, J. A., Stott, D. J., Swertz, M. A., Swift, A. J., Taylor, K. D., Tayo, B. O., Thorand, B., Thuillier, D., Tuomilehto, J., Uitterlinden, A. G., Vandenput, L., Vohl, M. C., Völzke, H., Vonk, J. M., Waeber, G., Waldenberger, M., Westendorp, R. G. J., Wild, S., Willemsen, G., Wolffenbuttel, B. H. R., Wong, A., Wright, A. F., Zhao, W., Zillikens, M. C., Baldassarre, D., Balkau, B., Bandinelli, S., Böger, C. A., Boomsma, D. I., Bouchard, C., Bruinenberg, M., Chasman, D. I., Ida Chen, Y. D., Chines, P. S., Cooper, R. S., Cucca, F., Cusi, D., De Faire, U., Ferrucci, L., Franks, P. W., Froguel, P., Gordon-Larsen, P., Grabe, H. J., Gudnason, V., Haiman, C. A., Hayward, C., Hveem, K., Johnson, A. D., Jukema, J. W., Kardia, S. L. R., Kivimaki, M., Kooner, J. S., Kuh, D., Laakso, M., Lehtimäki, T., Le Marchand, L., März, W., McCarthy, M. I., Metspalu, A., Morris, A. P., Ohlsson, C., Palmer, L. J., Pasterkamp, G., Pedersen, O., Peters, A., Peters, U., Polasek, O., Psaty, B. M., Qi, L., Rauramaa, R., Smith, B. H., Sorensen, T. I. A., Strauch, K., Tiemeier, H., Tremoli, E., Van Der Harst, P., Vestergaard, H., Vollenweider, P., Wareham, N. J., Weir, D. R., Whitfield, J. B., Wilson, J. F., Tyrrell, J., Frayling, T. M., Barroso, I., Boehnke, M., Deloukas, P., Fox, C. S., Hirschhorn, J. N., Hunter, D. J., Spector, T. D., Strachan, D. P., Van Duijn, C. M., Heid, I. M., Mohlke, K. L., Marchini, J., Loos, R. J. F., Kilpeläinen, T. O., Liu, C. T., Borecki, I. B., North, K. E. & Cupples, L. A., 26 Apr 2017, In: Nature Communications. 8, 14977.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    137 Citations (Scopus)
  • Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults

    Graff, M., Scott, R. A., Justice, A. E., Young, K. L., Feitosa, M. F., Barata, L., Winkler, T. W., Chu, A. Y., Mahajan, A., Hadley, D., Xue, L., Workalemahu, T., Heard-Costa, N. L., den Hoed, M., Ahluwalia, T. S., Qi, Q., Ngwa, J. S., Renström, F., Quaye, L., Eicher, J. D., & 233 othersHayes, J. E., Cornelis, M., Kutalik, Z., Lim, E., Luan, J., Huffman, J. E., Zhang, W., Zhao, W., Griffin, P. J., Haller, T., Ahmad, S., Marques-Vidal, P. M., Bien, S., Yengo, L., Teumer, A., Smith, A. V., Kumari, M., Harder, M. N., Justesen, J. M., Kleber, M. E., Hollensted, M., Lohman, K., Rivera, N. V., Whitfield, J. B., Zhao, J. H., Stringham, H. M., Lyytikäinen, L. P., Huppertz, C., Willemsen, G., Peyrot, W. J., Wu, Y., Kristiansson, K., Demirkan, A., Fornage, M., Hassinen, M., Bielak, L. F., Cadby, G., Tanaka, T., Mägi, R., Van Der Most, P. J., Jackson, A. U., Bragg-Gresham, J. L., Vitart, V., Marten, J., Navarro, P., Bellis, C., Pasko, D., Johansson, Å., Snitker, S., Cheng, C. Y., Eriksson, J., Lim, U., Aadahl, M., Adair, L. S., Amin, N., Balkau, B., Auvinen, J., Beilby, J., Bergman, R. N., Bergmann, S., Bertoni, A. G., Blangero, J., Bonnefond, A., Bonnycastle, L. L., Borja, J. B., Brage, S., Busonero, F., Buyske, S., Campbell, H., Chines, P. S., Collins, F. S., Corre, T., Smith, G. D., Delgado, G. E., Dueker, N., Dörr, M., Ebeling, T., Eiriksdottir, G., Esko, T., Faul, J. D., Fu, M., Færch, K., Gieger, C., Gläser, S., Gong, J., Gordon-Larsen, P., Grallert, H., Grammer, T. B., Grarup, N., van Grootheest, G., Harald, K., Hastie, N. D., Havulinna, A. S., Hernandez, D. G., Hindorff, L., Hocking, L. J., Holmens, O. L., Holzapfel, C., Hottenga, J. J., Huang, J., Huang, T., Hui, J., Huth, C., Hutri-Kähönen, N., James, A. L., Jansson, J. O., Jhun, M. A., Juonala, M., Kinnunen, L., Koistinen, H. A., Kolcic, I., Komulainen, P., Kuusisto, J., Kvaløy, K., Kähönen, M., Lakka, T. A., Launer, L. J., Lehne, B., Lindgren, C. M., Lorentzon, M., Luben, R. N., Marre, M., Milaneschi, Y., Monda, K. L., Montgomery, G. W., De Moor, M. H. M., Mulas, A., Müller-Nurasyid, M., Musk, A. W., Männikkö, R., Männistö, S., Narisu, N., Nauck, M., Nettleton, J. A., Nolte, I. M., Oldehinkel, A. J., Olden, M., Ong, K. K., Padmanabhan, S., Paternoster, L., Perez, J., Perola, M., Peters, A., Peters, U., Peyser, P. A., Prokopenko, I., Puolijoki, H., Raitakari, O. T., Rankinen, T., Rasmussen-Torvik, L. J., Rawal, R., Ridker, P. M., Rose, L. M., Rudan, I., Sarti, C., Sarzynski, M. A., Savonen, K., Scott, W. R., Sanna, S., Shuldiner, A. R., Sidney, S., Silbernagel, G., Smith, B. H., Smith, J. A., Snieder, H., Stančáková, A., Sternfeld, B., Swift, A. J., Tammelin, T., Tan, S. T., Thorand, B., Thuillier, D., Vandenput, L., Vestergaard, H., Van Vliet-Ostaptchouk, J. V., Vohl, M. C., Völker, U., Waeber, G., Walker, M., Wild, S. H., Wong, A., Wright, A. F., Zillikens, M. C., Zubair, N., Haiman, C. A., Lemarchand, L., Gyllensten, U., Ohlsson, C., Hofman, A., Rivadeneira, F., Uitterlinden, A. G., Pérusse, L., Wilson, J. F., Hayward, C., Polasek, O., Cucca, F., Hveem, K., Hartman, C. A., Tönjes, A., Bandinelli, S., Palmer, L. J., Kardia, S. L. R., Rauramaa, R., Sørensen, T. I. A., Tuomilehto, J., Salomaa, V., Penninx, B. W. J. H., De Geus, E. J. C. N., Boomsma, D. I., Lehtimäki, T., Mangino, M., Laakso, M., Bouchard, C., Martin, N. G., Kuh, D., Liu, Y., Linneberg, A., März, W., Strauch, K., Kivimäki, M., Harris, T. B., Gudnason, V., Völzke, H., Qi, L., Järvelin, M. R., Chambers, J. C., Kooner, J. S., Froguel, P., Kooperberg, C., Vollenweider, P., CHARGE consortium, EPIC-InterAct Consortium & PAGE Consortium, 1 Apr 2017, In: PLoS Genetics. 13, 4, e1006528.

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    145 Citations (Scopus)
    141 Downloads (Pure)
  • Influence of weather on incidence of bronchiolitis in Australia and New Zealand

    Hoeppner, T., Borland, M., Babl, F. E., Neutze, J., Phillips, N., Krieser, D., Dalziel, S. R., Davidson, A., Donath, S., Jachno, K., South, M., Williams, A., Zhang, G., Oakley, E. & Paediatric Research in Emergency Departments International Collaborative (PREDICT), 1 Oct 2017, In: Journal of Paediatrics and Child Health. 53, 10, p. 1000-1006 7 p.

    Research output: Contribution to journalArticlepeer-review

    8 Citations (Scopus)
  • Integrating personalised genomics into risk stratification models of population screening for colorectal cancer

    Cenin, D., O'Leary, P., Lansdorp-Vogelaar, I., Preen, D., Jenkins, M. & Moses, E., 1 Feb 2017, In: Australian and New Zealand Journal of Public Health. 41, 1, p. 3-4 2 p.

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    Open Access
    3 Citations (Scopus)
  • Longitudinal study of mammographic density measures that predict breast cancer risk

    Krishnan, K., Baglietto, L., Stone, J., Simpson, J. A., Severi, G., Evans, C. F., MacInnis, R. J., Giles, G. G., Apicella, C. & Hopper, J. L., 1 Apr 2017, In: Cancer Epidemiology Biomarkers and Prevention. 26, 4, p. 651-660 10 p.

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    37 Citations (Scopus)
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