Centre for Genetic Origins of Health and Diseases

2025

NMR spectroscopy derived plasma biomarkers of inflammation in human populations: Influences of age, sex and adiposity

Lodge, S., Masuda, R., Nitschke, P., Beilby, J. P., Hui, J., Hunter, M., Yeap, B. B., Millet, O., Wist, J., Nicholson, J. K. & Holmes, E., 6 Jan 2025, In: PLoS One. 20, 1 January, p. 1-15 15 p., e0311975.

Research output: Contribution to journal › Article › peer-review

Open Access

Statin effects on the lipidome: Predicting statin usage and implications for cardiovascular risk prediction

LIPID Study Investigators, May 2025, In: Journal of Lipid Research. 66, 5, 14 p., 100800.

Research output: Contribution to journal › Article › peer-review

Open Access

2024

A lipidomic based metabolic age score captures cardiometabolic risk independent of chronological age

Wang, T., Beyene, H. B., Yi, C., Cinel, M., Mellett, N. A., Olshansky, G., Meikle, T. G., Wu, J., Dakic, A., Watts, G. F., Hung, J., Hui, J., Beilby, J., Blangero, J., Kaddurah-Daouk, R., Salim, A., Moses, E. K., Shaw, J. E., Magliano, D. J. & Huynh, K. & 2 others, Giles, C. & Meikle, P. J., Jul 2024, In: EBioMedicine. 105, 18 p., 105199.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Citations (Scopus)

Development and validation of a plasmalogen score as an independent modifiable marker of metabolic health: population based observational studies and a placebo-controlled cross-over study

Beyene, H. B., Huynh, K., Wang, T., Paul, S., Cinel, M., Mellett, N. A., Olshansky, G., Meikle, T. G., Watts, G. F., Hung, J., Hui, J., Beilby, J., Blangero, J., Moses, E. K., Shaw, J. E., Magliano, D. J., Giles, C. & Meikle, P. J., Jul 2024, In: EBioMedicine. 105, 20 p., 105187.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Citations (Scopus)

Lipidomic Risk Score to Enhance Cardiovascular Risk Stratification for Primary Prevention

Wu, J., Giles, C., Dakic, A., Beyene, H. B., Huynh, K., Wang, T., Meikle, T., Olshansky, G., Salim, A., Duong, T., Watts, G. F., Hung, J., Hui, J., Cadby, G., Beilby, J., Blangero, J., Moses, E. K., Shaw, J. E., Magliano, D. J. & Zhu, D. & 11 others, Yang, J. Y., Grieve, S. M., Wilson, A., Chow, C. K., Vernon, S. T., Gray, M. P., Figtree, G. A., Carrington, M. J., Inouye, M., Marwick, T. H. & Meikle, P. J., 30 Jul 2024, In: Journal of the American College of Cardiology. 84, 5, p. 434-446 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Citations (Scopus)

Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications

Sterenborg, R. B. T. M., Steinbrenner, I., Li, Y., Bujnis, M. N., Naito, T., Marouli, E., Galesloot, T. E., Babajide, O., Andreasen, L., Astrup, A., Åsvold, B. O., Bandinelli, S., Beekman, M., Beilby, J. P., Bork-Jensen, J., Boutin, T., Brody, J. A., Brown, S. J., Brumpton, B. & Campbell, P. J. & 121 others, Cappola, A. R., Ceresini, G., Chaker, L., Chasman, D. I., Concas, M. P., Coutinho de Almeida, R., Cross, S. M., Cucca, F., Deary, I. J., Kjaergaard, A. D., Echouffo Tcheugui, J. B., Ellervik, C., Eriksson, J. G., Ferrucci, L., Freudenberg, J., Fuchsberger, C., Gieger, C., Giulianini, F., Gögele, M., Graham, S. E., Grarup, N., Gunjača, I., Hansen, T., Harding, B. N., Harris, S. E., Haunsø, S., Hayward, C., Hui, J., Ittermann, T., Jukema, J. W., Kajantie, E., Kanters, J. K., Kårhus, L. L., Kiemeney, L. A. L. M., Kloppenburg, M., Kühnel, B., Lahti, J., Langenberg, C., Lapauw, B., Leese, G., Li, S., Liewald, D. C. M., Linneberg, A., Lominchar, J. V. T., Luan, J., Martin, N. G., Matana, A., Meima, M. E., Meitinger, T., Meulenbelt, I., Mitchell, B. D., Møllehave, L. T., Mora, S., Naitza, S., Nauck, M., Netea-Maier, R. T., Noordam, R., Nursyifa, C., Okada, Y., Onano, S., Papadopoulou, A., Palmer, C. N. A., Pattaro, C., Pedersen, O., Peters, A., Pietzner, M., Polašek, O., Pramstaller, P. P., Psaty, B. M., Punda, A., Ray, D., Redmond, P., Richards, J. B., Ridker, P. M., Russ, T. C., Ryan, K. A., Olesen, M. S., Schultheiss, U. T., Selvin, E., Siddiqui, M. K., Sidore, C., Slagboom, P. E., Sørensen, T. I. A., Soto-Pedre, E., Spector, T. D., Spedicati, B., Srinivasan, S., Starr, J. M., Stott, D. J., Tanaka, T., Torlak, V., Trompet, S., Tuhkanen, J., Uitterlinden, A. G., van den Akker, E. B., van den Eynde, T., van der Klauw, M. M., van Heemst, D., Verroken, C., Visser, W. E., Vojinovic, D., Völzke, H., Waldenberger, M., Walsh, J. P., Wareham, N. J., Weiss, S., Willer, C. J., Wilson, S. G., Wolffenbuttel, B. H. R., Wouters, H. J. C. M., Wright, M. J., Yang, Q., Zemunik, T., Zhou, W., Zhu, G., Zöllner, S., Smit, J. W. A., Peeters, R. P., Köttgen, A., Teumer, A. & Medici, M., 30 Jan 2024, In: Nature Communications. 15, 1, 18 p., 888.

Research output: Contribution to journal › Article › peer-review

Open Access

34 Citations (Scopus)

2023

Author Correction: Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk (Nature Genetics, (2023), 55, 3, (410-422), 10.1038/s41588-023-01314-0)

The Qatar Genome Program Research (QGPR) Consortium, Biobank and Sample Preparation, Sequencing and Genotyping group, Applied Bioinformatics Core, Data Management and Computing Infrastructure group, Consortium Lead Principal Investigators & China Kadoorie Biobank Collaborative Group, Oct 2023, In: Nature Genetics. 55, 10, p. 1778-1779 2 p.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

Genetic variants of TLR4, including the novel variant, rs5030719, and related genes are associated with susceptibility to clinical malaria in African children

Ariff, A., Song, Y., Aguilar, R., Nhabomba, A., Manaca, M. N., Khoo, S. K., Wiertsema, S., Bassat, Q., Barbosa, A., Quintó, L., Laing, I. A., Guinovart, C., Alonso, P. L., Dobaño, C., Le Souëf, P. & Zhang, G., Dec 2023, In: Malaria Journal. 22, 1, 177.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Citation (Scopus)

Metabolic phenotyping of BMI to characterize cardiometabolic risk: evidence from large population-based cohorts

Beyene, H. B., Giles, C., Huynh, K., Wang, T., Cinel, M., Mellett, N. A., Olshansky, G., Meikle, T. G., Watts, G. F., Hung, J., Hui, J., Cadby, G., Beilby, J., Blangero, J., Moses, E. K., Shaw, J. E., Magliano, D. J. & Meikle, P. J., Dec 2023, In: Nature Communications. 14, 1, 6280.

Research output: Contribution to journal › Article › peer-review

Open Access

30 Citations (Scopus)

Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk

China Kadoorie Biobank Collaborative Group, Qatar Genome Program Research (QGPR) Consortium, Shrine, N., Izquierdo, A. G., Chen, J., Packer, R., Hall, R. J., Guyatt, A. L., Batini, C., Thompson, R. J., Pavuluri, C., Malik, V., Hobbs, B. D., Moll, M., Kim, W., Tal-Singer, R., Bakke, P., Fawcett, K. A., John, C. & Coley, K. & 130 others, Piga, N. N., Pozarickij, A., Lin, K., Millwood, I. Y., Chen, Z., Li, L., Wijnant, S. R. A., Lahousse, L., Brusselle, G., Uitterlinden, A. G., Manichaikul, A., Oelsner, E. C., Rich, S. S., Barr, R. G., Kerr, S. M., Vitart, V., Brown, M. R., Wielscher, M., Imboden, M., Jeong, A., Bartz, T. M., Gharib, S. A., Flexeder, C., Karrasch, S., Gieger, C., Peters, A., Stubbe, B., Hu, X., Ortega, V. E., Meyers, D. A., Bleecker, E. R., Gabriel, S. B., Gupta, N., Smith, A. V., Luan, J., Zhao, J. H., Hansen, A. F., Langhammer, A., Willer, C., Bhatta, L., Porteous, D., Smith, B. H., Campbell, A., Sofer, T., Lee, J., Daviglus, M. L., Yu, B., Lim, E., Xu, H., O'Connor, G. T., Thareja, G., Albagha, O. M. E., Suhre, K., Granell, R., Faquih, T. O., Hiemstra, P. S., Slats, A. M., Mullin, B. H., Hui, J., James, A., Beilby, J., Patasova, K., Hysi, P., Koskela, J. T., Wyss, A. B., Jin, J., Sikdar, S., Lee, M., May-Wilson, S., Pirastu, N., Kentistou, K. A., Joshi, P. K., Timmers, P. R. H. J., Williams, A. T., Free, R. C., Wang, X., Morrison, J. L., Gilliland, F. D., Chen, Z., Wang, C. A., Foong, R. E., Harris, S. E., Taylor, A., Redmond, P., Cook, J. P., Mahajan, A., Lind, L., Palviainen, T., Lehtimäki, T., Raitakari, O. T., Kaprio, J., Rantanen, T., Pietiläinen, K. H., Cox, S. R., Pennell, C. E., Hall, G. L., Gauderman, W. J., Brightling, C., Wilson, J. F., Vasankari, T., Laitinen, T., Salomaa, V., Mook-Kanamori, D. O., Timpson, N. J., Zeggini, E., Dupuis, J., Hayward, C., Brumpton, B., Langenberg, C., Weiss, S., Homuth, G., Schmidt, C. O., Probst-Hensch, N., Jarvelin, M. R., Morrison, A. C., Polasek, O., Rudan, I., Lee, J. H., Sayers, I., Rawlins, E. L., Dudbridge, F., Silverman, E. K., Strachan, D. P., Walters, R. G., Morris, A. P., London, S. J., Cho, M. H., Wain, L. V., Hall, I. P. & Tobin, M. D., Mar 2023, In: Nature Genetics. 55, 3, p. 410-422 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

73 Citations (Scopus)

Plasma lipoprotein subclass variation in middle-aged and older adults: Sex-stratified distributions and associations with health status and cardiometabolic risk factors

Masuda, R., Wist, J., Lodge, S., Kimhofer, T., Hunter, M., Hui, J., Beilby, J. P., Burnett, J. R., Dwivedi, G., Schlaich, M. P., Bong, S. H., Loo, R. L., Holmes, E., Nicholson, J. K. & Yeap, B. B., 1 Sept 2023, In: Journal of Clinical Lipidology. 17, 5, p. 677-687 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Citations (Scopus)

Serum 21-deoxycortisol for diagnosis of non-classic congenital adrenal hyperplasia in women with androgen excess

Ng, J. L., Lim, E. M., Zhang, R., Beilby, J. P., Watts, G. F., Brown, S. J. & Stuckey, B. G. A., 1 Dec 2023, In: The Journal of clinical endocrinology and metabolism. 108, 12, p. e1560-e1570

Research output: Contribution to journal › Article › peer-review

Open Access

4 Citations (Scopus)

Serum testosterone and sex hormone-binding globulin are inversely associated with leucocyte telomere length in men: a cross-sectional analysis of the UK Biobank Study

Marriott, R. J., Murray, K., Budgeon, C. A., Codd, V., Hui, J., Arscott, G. M., Beilby, J. P., Hankey, G. J., Wittert, G. A., Wu, F. C. W. & Yeap, B. B., 14 Feb 2023, In: European Journal of Endocrinology. 188, 2, p. 1-12

Research output: Contribution to journal › Article › peer-review

Open Access

6 Citations (Scopus)

2022

Common genetic variants do not predict recurrent events in coronary heart disease patients

Thompson, P. L., Hui, J., Beilby, J., Palmer, L. J., Watts, G. F., West, M. J., Kirby, A., Marschner, S., Simes, R. J., Sullivan, D. R., White, H. D., Stewart, R. & Tonkin, A. M., Dec 2022, In: BMC Cardiovascular Disorders. 22, 1, 96.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Citation (Scopus)

Shariant platform: Enabling evidence sharing across Australian clinical genetic-testing laboratories to support variant interpretation

Tudini, E., Andrews, J., Lawrence, D. M., King-Smith, S. L., Baker, N., Baxter, L., Beilby, J., Bennetts, B., Beshay, V., Black, M., Boughtwood, T. F., Brion, K., Cheong, P. L., Christie, M., Christodoulou, J., Chong, B., Cox, K., Davis, M. R., Dejong, L. & Dinger, M. E. & 49 others, Doig, K. D., Douglas, E., Dubowsky, A., Ellul, M., Fellowes, A., Fisk, K., Fortuno, C., Friend, K., Gallagher, R. L., Gao, S., Hackett, E., Hadler, J., Hipwell, M., Ho, G., Hollway, G., Hooper, A. J., Kassahn, K. S., Krishnaraj, R., Lau, C., Le, H., San Leong, H., Lundie, B., Lunke, S., Marty, A., McPhillips, M., Nguyen, L. T., Nones, K., Palmer, K., Pearson, J. V., Quinn, M. C. J., Rawlings, L. H., Sadedin, S., Sanchez, L., Schreiber, A. W., Sigalas, E., Simsek, A., Soubrier, J., Stark, Z., Thompson, B. A., U, J., Vakulin, C. G., Wells, A. V., Wise, C. A., Woods, R., Ziolkowski, A., Brion, M. J., Scott, H. S., Thorne, N. P. & Spurdle, A. B., 3 Nov 2022, In: American Journal of Human Genetics. 109, 11, p. 1960-1973 14 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

17 Citations (Scopus)

Validation of ICD-10-AM Coding for Myocardial Infarction Subtype in Hospitalisation Data

Nedkoff, L., Lopez, D., Hung, J., Knuiman, M., Briffa, T. G., Murray, K., Davis, E., Aria, S., Robinson, K., Beilby, J., Hobbs, M. S. T. & Sanfilippo, F. M., Jun 2022, In: Heart Lung and Circulation. 31, 6, p. 849-858 10 p.

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

2021

Further heterogeneity in Silver–Russell syndrome: PLAG1 deletion in association with a complex chromosomal rearrangement

Brereton, R. E., Nickerson, S. L., Woodward, K. J., Edwards, T., Sivamoorthy, S., Ramos Vasques Walters, F., Chabros, V., Marchin, V., Grumball, T., Kennedy, D., Uzaraga, J., Peverall, J., Arscott, G., Beilby, J., Choong, C. S., Townshend, S. & Azmanov, D. N., Oct 2021, In: American Journal of Medical Genetics Part A. 185, 10, p. 3136-3145 10 p.

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

2020

Interval breast cancer risk associations with breast density, family history and breast tissue aging

Nguyen, T. L., Li, S., Dite, G. S., Aung, Y. K., Evans, C. F., Trinh, H. N., Baglietto, L., Stone, J., Song, Y. M., Sung, J., English, D. R., Jenkins, M. A., Dugué, P. A., Milne, R. L., Southey, M. C., Giles, G. G., Pike, M. C. & Hopper, J. L., 15 Jul 2020, In: International Journal of Cancer. 147, 2, p. 375-382 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Citations (Scopus)

Machine learning-based dna methylation score for fetal exposure to maternal smoking: Development and validation in samples collected from adolescents and adults

Rauschert, S., Melton, P. E., Heiskala, A., Karhunen, V., Burdge, G., Craig, J. M., Godfrey, K. M., Lillycrop, K., Mori, T. A., Beilin, L. J., Oddy, W. H., Pennell, C., Järvelin, M. R., Sebert, S. & Huang, R. C., Sept 2020, In: Environmental Health Perspectives. 128, 9, p. 1-11 11 p., 097003.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Citations (Scopus)

RNA sequencing profiling potential biomarkers for nut allergy

Lee, K. H., Song, Y., O'Sullivan, M., Metcalfe, J., Loh, R. & Zhang, G., Aug 2020, In: World Allergy Organization Journal. 13, 8, p. 45-46 100408.

Research output: Contribution to journal › Abstract/Meeting Abstract › peer-review

Open Access

2019

Analysis of the Epigenome in Multiplex Pre-eclampsia Families Identifies SORD, DGKI, and ICA1 as Novel Candidate Risk Genes

Ariff, A., Melton, P. E., Brennecke, S. P. & Moses, E. K., 19 Mar 2019, In: Frontiers in Genetics. 10, MAR, 11 p., 227.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Citations (Scopus)

Development and validation of a targeted gene sequencing panel for application to disparate cancers

kConFab Investigators, 1 Dec 2019, In: Scientific Reports. 9, 1, 17052.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Citations (Scopus)

Differential SLC6A4 methylation: a predictive epigenetic marker of adiposity from birth to adulthood

EpiGen Consortium, 1 May 2019, In: International Journal of Obesity. 43, 5, p. 974-988 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Citations (Scopus)

Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer

EMBRACE Collaborators, GC-HBOC Study Collaborators, GEMO Study Collaborators, ABCTB Investigators, HEBON Investigators, BCFR Investigators & Stone, J., 1 Dec 2019, In: Nature Communications. 10, 1, 1741.

Research output: Contribution to journal › Article › peer-review

Open Access

86 Citations (Scopus)

Genome-wide association meta-analysis of autistic traits in the general population

Bralten, J., Cadby, G., Jones, R., Whitehouse, A., Moses, E., Shumskaya, E., Buitelaar, J., Franke, B. & Poelmans, G., 2019, In: European Neuropsychopharmacology. 29, p. S754-S754 1 p.

Research output: Contribution to journal › Abstract/Meeting Abstract › peer-review

2 Citations (Web of Science)

Genome-wide association study of peripheral blood DNA methylation and conventional mammographic density measures

Li, S., Dugué, P. A., Baglietto, L., Severi, G., Wong, E. M., Nguyen, T. L., Stone, J., English, D. R., Southey, M. C., Giles, G. G., Hopper, J. L. & Milne, R. L., 1 Oct 2019, In: International Journal of Cancer. 145, 7, p. 1768-1773 6 p.

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Identification of novel sarcoma risk genes using a two-stage genome wide DNA sequencing strategy in cancer cluster families and population case and control cohorts

International Sarcoma Kindred Study, 3 May 2019, In: BMC Medical Genetics. 20, 1, 10 p., 69.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Citations (Scopus)

Inference about causation between body mass index and DNA methylation in blood from a twin family study

Li, S., Wong, E. M., Bui, M., Nguyen, T. L., Joo, J. H. E., Stone, J., Dite, G. S., Dugué, P. A., Milne, R. L., Giles, G. G., Saffery, R., Southey, M. C. & Hopper, J. L., 1 Feb 2019, In: International Journal of Obesity. 43, 2, p. 243-252 10 p.

Research output: Contribution to journal › Article › peer-review

48 Citations (Scopus)

Measurement challenge: protocol for international case-control comparison of mammographic measures that predict breast cancer risk

Dench, E., Bond-Smith, D., Darcey, E., Lee, G., Aung, Y. K., Chan, A., Cuzick, J., Ding, Z. Y., Evans, C. F., Harvey, J., Highnam, R., Hsieh, M. K., Kontos, D., Li, S., Mariapun, S., Nickson, C., Nguyen, T. L., Pertuz, S., Procopio, P. & Rajaram, N. & 12 others, Repich, K., Tan, M., Teo, S. H., Trinh, N. H., Ursin, G., Wang, C., Dos-Santos-Silva, I., McCormack, V., Nielsen, M., Shepherd, J., Hopper, J. L. & Stone, J., 31 Dec 2019, In: BMJ Open. 9, 12, p. e031041 e031041.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Citations (Scopus)

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight

Küpers, L. K., Monnereau, C., Sharp, G. C., Yousefi, P., Salas, L. A., Ghantous, A., Page, C. M., Reese, S. E., Wilcox, A. J., Czamara, D., Starling, A. P., Novoloaca, A., Lent, S., Roy, R., Hoyo, C., Breton, C. V., Allard, C., Just, A. C., Bakulski, K. M. & Holloway, J. W. & 107 others, Everson, T. M., Xu, C. J., Huang, R. C., van der Plaat, D. A., Wielscher, M., Merid, S. K., Ullemar, V., Rezwan, F. I., Lahti, J., van Dongen, J., Langie, S. A. S., Richardson, T. G., Magnus, M. C., Nohr, E. A., Xu, Z., Duijts, L., Zhao, S., Zhang, W., Plusquin, M., DeMeo, D. L., Solomon, O., Heimovaara, J. H., Jima, D. D., Gao, L., Bustamante, M., Perron, P., Wright, R. O., Hertz-Picciotto, I., Zhang, H., Karagas, M. R., Gehring, U., Marsit, C. J., Beilin, L. J., Vonk, J. M., Jarvelin, M. R., Bergström, A., Örtqvist, A. K., Ewart, S., Villa, P. M., Moore, S. E., Willemsen, G., Standaert, A. R. L., Håberg, S. E., Sørensen, T. I. A., Taylor, J. A., Räikkönen, K., Yang, I. V., Kechris, K., Nawrot, T. S., Silver, M. J., Gong, Y. Y., Richiardi, L., Kogevinas, M., Litonjua, A. A., Eskenazi, B., Huen, K., Mbarek, H., Maguire, R. L., Dwyer, T., Vrijheid, M., Bouchard, L., Baccarelli, A. A., Croen, L. A., Karmaus, W., Anderson, D., de Vries, M., Sebert, S., Kere, J., Karlsson, R., Arshad, S. H., Hämäläinen, E., Routledge, M. N., Boomsma, D. I., Feinberg, A. P., Newschaffer, C. J., Govarts, E., Moisse, M., Fallin, M. D., Melén, E., Prentice, A. M., Kajantie, E., Almqvist, C., Oken, E., Dabelea, D., Boezen, H. M., Melton, P. E., Wright, R. J., Koppelman, G. H., Trevisi, L., Hivert, M. F., Sunyer, J., Munthe-Kaas, M. C., Murphy, S. K., Corpeleijn, E., Wiemels, J., Holland, N., Herceg, Z., Binder, E. B., Davey Smith, G., Jaddoe, V. W. V., Lie, R. T., Nystad, W., London, S. J., Lawlor, D. A., Relton, C. L., Snieder, H. & Felix, J. F., 1 Dec 2019, In: Nature Communications. 10, 1, 1893.

Research output: Contribution to journal › Article › peer-review

Open Access

149 Citations (Scopus)

Methodological challenges and updated findings from a meta-analysis of the association between mammographic density and breast cancer

Bond-Smith, D. & Stone, J., Jan 2019, In: Cancer Epidemiology, Biomarkers & Prevention. 28, 1, p. 22-31 10 p.

Research output: Contribution to journal › Review article › peer-review

37 Citations (Scopus)

Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways (vol 9, 4774, 2018)

Melanoma GWAS Consortium, 14 Jan 2019, In: Nature Communications. 10, 3 p., 299.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

4 Citations (Web of Science)

Statins do not directly inhibit the activity of major epigenetic modifying enzymes

Bridgeman, S., Northrop, W., Ellison, G., Sabapathy, T., Melton, P. E., Newsholme, P. & Mamotte, C. D. S., 10 Apr 2019, In: Cancers. 11, 4, 516.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Citations (Scopus)

The association between mammographic density and breast cancer risk in Western Australian Aboriginal women

Darcey, E., Lloyd, R., Cadby, G., Pilkington, L., Redfern, A., Thompson, S. C., Saunders, C., Wylie, E. & Stone, J., 15 Jul 2019, In: Breast Cancer Research and Treatment. 176, 1, p. 235-242 8 p.

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

2018

Airway function in infancy is linked to airflow measurements and respiratory symptoms from childhood into adulthood

Owens, L., Laing, I. A., Zhang, G., Turner, S. & Le Souëf, P. N., 1 Aug 2018, In: Pediatric Pulmonology. 53, 8, p. 1082-1088 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

25 Citations (Web of Science)

Causal effect of smoking on DNA methylation in peripheral blood: A twin and family study

Li, S., Wong, E. M., Bui, M., Nguyen, T. L., Joo, J. H. E., Stone, J., Dite, G. S., Giles, G. G., Saffery, R., Southey, M. C. & Hopper, J. L., 9 Feb 2018, In: Clinical Epigenetics. 10, 1, 18.

Research output: Contribution to journal › Article › peer-review

Open Access

77 Citations (Scopus)

Cell-type-specific eQTL of primary melanocytes facilitates identification of melanoma susceptibility genes

Zhang, T., Choi, J., Kovacs, M. A., Shi, J., Xu, M., NISC Comparative Sequencing, Melanoma Meta-Anal Consortium, Goldstein, A. M., Trower, A. J., Bishop, D. T., Iles, M. M., Duffy, D. L., MacGregor, S., Amundadottir, L. T., Law, M. H., Loftus, S. K., Pavan, W. J. & Brown, K. M., Nov 2018, In: Genome Research. 28, 11, p. 1621-1635 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

58 Citations (Scopus)

Cellular and molecular mechanisms of vitamin D in food allergy

Poole, A., Song, Y., Brown, H., Hart, P. H. & Zhang, G., 1 Jul 2018, In: Journal of Cellular and Molecular Medicine. 22, 7, p. 3270-3277 8 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

45 Citations (Scopus)

Clinical significance of circulating microRNAs as markers in detecting and predicting congenital heart defects in children

Song, Y., Higgins, H., Guo, J., Harrison, K., Schultz, E. N., Hales, B. J., Moses, E. K., Goldblatt, J., Pachter, N. & Zhang, G., 27 Feb 2018, In: Journal of Translational Medicine. 16, 1, 42.

Research output: Contribution to journal › Article › peer-review

Open Access

37 Citations (Scopus)

Cord Blood IL-12 Confers Protection to Clinical Malaria in Early Childhood Life

Song, Y., Aguilar, R., Guo, J., Manaca, M. N., Nhabomba, A., Berthoud, T. K., Khoo, S. K., Wiertsema, S., Barbosa, A., Quintó, L., Laing, I. A., Mayor, A., Guinovart, C., Alonso, P. L., Lesouëf, P. N., Dobaño, C. & Zhang, G. B., 1 Dec 2018, In: Scientific Reports. 8, 1, 10860.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Citation (Scopus)

Cuffed vs. uncuffed tracheal tubes in children: a randomised controlled trial comparing leak, tidal volume and complications

Chambers, N. A., Ramgolam, A., Sommerfield, D., Zhang, G., Ledowski, T., Thurm, M., Lethbridge, M., Hegarty, M. K. & von Ungern-Sternberg, B. S., 1 Feb 2018, In: Anaesthesia. 73, 2, p. 160-168 9 p.

Research output: Contribution to journal › Article › peer-review

59 Citations (Scopus)

Epigenetics, heritability and longitudinal analysis

Nustad, H. E., Almeida, M., Canty, A. J., LeBlanc, M., Page, C. M. & Melton, P. E., 17 Sept 2018, In: BMC Genetics. 19, Suppl 1, p. 77 77.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Citations (Scopus)

Genetic approaches in preeclampsia

Yong, H. E. J., Murthi, P., Brennecke, S. P. & Moses, E. K., 1 Jan 2018, Genetic Approaches in Preeclampsia. Murthi, P. & Vaillancourt, C. (eds.). Humana Press Inc., Vol. 1710. p. 53-72 20 p. (Methods in Molecular Biology; vol. 1710).

Research output: Chapter in Book/Conference paper › Chapter › peer-review

28 Citations (Scopus)

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation

LifeLines Cohort Study, 1 Dec 2018, In: Nature Communications. 9, 1, 4455.

Research output: Contribution to journal › Article › peer-review

Open Access

213 Citations (Scopus)

Genome-wide average DNA methylation is determined in utero

Li, S., Wong, E. M., Dugué, P. A., McRae, A. F., Kim, E., Joo, J. H. E., Nguyen, T. L., Stone, J., Dite, G. S., Armstrong, N. J., Mather, K. A., Thalamuthu, A., Wright, M. J., Ames, D., Milne, R. L., Craig, J. M., Saffery, R., Montgomery, G. W., Song, Y.-M. & Sung, J. & 5 others, Spector, T. D., Sachdev, P. S., Giles, G. G., Southey, M. C. & Hopper, J. L., 1 Jun 2018, In: International Journal of Epidemiology. 47, 3, p. 908-916 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

33 Citations (Scopus)

Identification of Pre-eclampsia susceptibility genes

Gokhale-Agashe, D. S., 2018, (Unpublished)

Research output: Thesis › Doctoral Thesis

File

620 Downloads (Pure)

InforMD: A new initiative to raise public awareness about breast density

Hugo, H. J., Zysk, A., Dasari, P., Britt, K., Hopper, J. L., Stone, J., Thompson, E. W. & Ingman, W. V., 6 Feb 2018, In: ecancermedicalscience. 12, 807.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Citations (Scopus)

Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways

Melanoma GWAS Consortium, 1 Dec 2018, In: Nature Communications. 9, 1, 4774.

Research output: Contribution to journal › Article › peer-review

Open Access

88 Citations (Scopus)

PCR screening of antimicrobial resistance genes in faecal samples from Australian and Chinese children

Ravensdale, J. T., Xian, D. T. W., Wei, C. M., Lv, Q., Wen, X., Guo, J., Coorey, R., LeSouëf, P., Lu, F., Zhang, G. & Dykes, G. A., 1 Sept 2018, In: Journal of Global Antimicrobial Resistance. 14, p. 178-181 4 p.

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Prevalence of allergic sensitization, hay fever, eczema, and asthma in a longitudinal birth cohort

Owens, L., Laing, I. A., Zhang, G., Turner, S. & Le Souëf, P. N., 1 Jan 2018, In: Journal of Asthma and Allergy. 11, p. 173-180 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Citations (Scopus)

Centre for Genetic Origins of Health and Diseases

Research output

Search results