Equipments Details
Description
The VevoLazrX high frequency transducers (10-71MHz) deliver an acoustic pulse into the small animal’s body. Tissues of different densities absorb and reflect sound waves differently resulting in high-resolution grayscale images/ 3D clips, when the partially reflected sound waves return to the transducer.
Photoacoustic imaging allows the delivery of light energy that is absorbed by tissues causing a thermoelastic expansion. This expansion then generates ultrasound waves that are detected by the transducer and produce images of optical absorption contrast within tissues. New laser technology provides faster, more sensitive image acquisition at a wider wavelength range (680 - 970 nm and 1200 - 2000 nm).
Capabilities:
•3D Imaging/ 4D Imaging
•Colour (Velocity)/ Power Doppler (3D)
•Pulse Wave Doppler Mode / Tissue Doppler Mode
•Contrast Agent Detection- Microbubble injection for perfusion studies
•Nanoparticle Detection
•Total haemoglobin content and quantification
•Oxygen saturation calculation and quantification
•Vevo Multiplexer Management of photoacoustic signal from multiple sources on the same image. Includes spectral unmixing
•Spectral Unmixing Compound characterization algorithm to delineate and quantify oxygenated and deoxygenated blood and various contrast agents
•Strain Analysis package
•Cardiac Analysis package
To cite this equipment/component: Centre for Microscopy, Characterisation & Analysis. (2018). VevoLazrX High Frequency Ultrasound and Photoacoustic Imaging. University of Western Australia. https://doi.org/10.26182/D098-FP91
Photoacoustic imaging allows the delivery of light energy that is absorbed by tissues causing a thermoelastic expansion. This expansion then generates ultrasound waves that are detected by the transducer and produce images of optical absorption contrast within tissues. New laser technology provides faster, more sensitive image acquisition at a wider wavelength range (680 - 970 nm and 1200 - 2000 nm).
Capabilities:
•3D Imaging/ 4D Imaging
•Colour (Velocity)/ Power Doppler (3D)
•Pulse Wave Doppler Mode / Tissue Doppler Mode
•Contrast Agent Detection- Microbubble injection for perfusion studies
•Nanoparticle Detection
•Total haemoglobin content and quantification
•Oxygen saturation calculation and quantification
•Vevo Multiplexer Management of photoacoustic signal from multiple sources on the same image. Includes spectral unmixing
•Spectral Unmixing Compound characterization algorithm to delineate and quantify oxygenated and deoxygenated blood and various contrast agents
•Strain Analysis package
•Cardiac Analysis package
To cite this equipment/component: Centre for Microscopy, Characterisation & Analysis. (2018). VevoLazrX High Frequency Ultrasound and Photoacoustic Imaging. University of Western Australia. https://doi.org/10.26182/D098-FP91
Research technique
- Ultrasound imaging
- Photoacoustic imaging
- Live animal imaging

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