Shimadzu CLAM-2030 LCMS-8060 System

    Facility/equipment: Equipment

    • LocationShow on map

      CMCA@Perkins, (M519), Level 3, Harry Perkins Institute of Medical Research, 6 Verdun St, Perth

      Australia

    Equipments Details

    Description

    The Shimadzu Clinical Laboratory Automated sample preparation Module (CLAM-2030) is a fully automated sample preparation module based on extensive blood coagulation analyser technology. The CLAM-2030 integrates with Ultra High Performance Liquid Chromatography/Mass Spectrometer (UHPLC-MS) instruments, enabling the CLAM-2030 to sample directly from tubes and blood tubes, perform basic processing steps and then introduce the prepared aliquot to the UHPLC prior to analysis by the ultra-sensitive LCMS-8060 triple quadrupole mass spectrometer (LCMS-8060 also functions as a stand-alone instrument). This simplifies the use of high end instrumentation and improves efficiency for the throughput of laboratory samples, as well as reducing the risk of sample error by use of bar coding technology.

    Techniques
    •Targeted metabolite analysis
    •Drug pharmacokinetics
    •Steroid profiling in blood serum (CLAM) or multiple sample types (LCMS)

    Instrument (MS) Specifications
    •2D UPLC performance
    •Excellent sensitivity for many applications, particularly for negative polarity
    •5ms polarity switching to detect more compounds, more efficiently
    •Fully automated MRM optimisation to improve compound detection

    To cite this equipment/component: Centre for Microscopy, Characterisation & Analysis. (2025). Shimadzu CLAM-2030 LCMS-8060 System. The University of Western Australia. https://doi.org/10.26182/10AZ-V305

    Research technique

    • 2-dimensional liquid chromatography
    • Multiple reaction monitoring
    • Electrospray ionisation (ESI)
    Shimadzu CLAM-2030 LCMS-8060 System

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