A Computational Model of Achilles Tendon Adaptive Remodelling

Research output: ThesisMaster's Thesis

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  • THESIS - MASTER BY RESEARCH - YOUNG Stuart Richard - 2017

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Abstract

To date there is no basic theoretical framework describing how tendon maintains tissue homeostasis consistent with lhe experimental data, or how tendon adapts to its environmental load conditions.
Based on established biological principles of tendon damage and repair, I develop a dynamic model of tendon homeostasis capable of adaptation. This research shows that for a model soleus musculotendon unit, the model tendon is 'capable' of dynamically adjusting to find an equilibrium tendon geometry, which coincides with minimum metabolic cost of muscle activation. This model presents an exciting first step to understanding the complex process of tendon homeostasis and adaptation In-vivo.
Original languageEnglish
QualificationMasters
Awarding Institution
Award date6 Oct 2017
DOIs
StateUnpublished - 2017


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